Dynamic Behavioral Mixed-Membership Model for Large Evolving Networks

The majority of real-world networks are dynamic and extremely large (e.g., Internet Traffic, Twitter, Facebook, ...). To understand the structural behavior of nodes in these large dynamic networks, it may be necessary to model the dynamics of behavioral roles representing the main connectivity patterns over time. In this paper, we propose a dynamic behavioral mixed-membership model (DBMM) that captures the roles of nodes in the graph and how they evolve over time. Unlike other node-centric models, our model is scalable for analyzing large dynamic networks. In addition, DBMM is flexible, parameter-free, has no functional form or parameterization, and is interpretable (identifies explainable patterns). The performance results indicate our approach can be applied to very large networks while the experimental results show that our model uncovers interesting patterns underlying the dynamics of these networks

Experimental determination of lift and drag coefficients for the initial stages of inflation of the X-38 parafoil

The NASA X-38 Crew Return Vehicle (CRV) is a vehicle designed to act as an emergency lifeboat for the International Space Station (ISS) in the case of a medical emergency or the need to evacuate the structure. Modeled after the Martin Marietta X-23A lifting body, the vehicle employs a large parafoil to enable the craft to land safely and within a short distance of a designated area. A recently completed joint effort between ISU and NASA/JSC has provided preliminary experimental data dealing with the aerodynamic forces that act on the recovery parafoil. A hard cast model of one segment of the parafoil in a first stage deployment state was provided by JSC researchers to be tested in an ISU wind tunnel. Lift and drag forces were measured over a wide range of angles of attack for each of several Reynolds numbers. Wind tunnel tests indicate that the parafoil in a first stage deployment state behaves much like a flap plate. The results obtained in this effort will help researchers better understand parafoil inflation dynamics and provide comparative data for tuning CFD tools for future parafoil deployment simulations

Character of the diatom assemblage spanning a depositional transition in the Eastern Equatorial Pacific Ocean at 6.6 Ma

Approximately 6.6 million years ago in the Eastern Equatorial Pacific a large increase in biogenic mass accumulation rates (MARs) occurred. This increased level of biogenic mass accumulation persisted until about 4.4 Ma at which time levels returned to those similar to before the transition at 6.6 Ma. The exact nature of the change that facilitated this transition in biogenic MARs, however, was not understood. Here we present the results of a study which characterizes the diatom assemblage spanning the depositional transition at 6.6 Ma from sediments taken from ODP Hole 850B. A close inspection of lithology reveals a clear change in lithology from a diatom nannofossil ooze to a nannofossil diatom ooze at 6.6 Ma. This transition is immediately followed by the occurrence of laminated diatom ooze (LDO). Diatom absolute abundance data reveals three levels of productivity associated with pre-transitional, post-transitional, and LDO formational sediments. An increase in the absolute abundance of Thalassionema nitzschioides was the major contributor to the formation of post-transitional, and LDO sediments. The known ecological preferences of this species indicate an overall increase in nutrient availability followed by sporadic changes in nutrient availability. These changes in nutrient availability could be associated with the establishment, or increase in strength, of an upwelling cell and/or the increase in nutrients made available via upwelling due to a shoaling of the thermocline

Characterization of Pro-Inflammatory Flagellin Proteins Produced by Lactobacillus ruminis and Related Motile Lactobacilli

peer-reviewedLactobacillus ruminis is one of at least twelve motile but poorly characterized species found in the genus Lactobacillus. Of these, only L. ruminis has been isolated from mammals, and this species may be considered as an autochthonous member of the gastrointestinal microbiota of humans, pigs and cows. Nine L. ruminis strains were investigated here to elucidate the biochemistry and genetics of Lactobacillus motility. Six strains isolated from humans were non-motile while three bovine isolates were motile. A complete set of flagellum biogenesis genes was annotated in the sequenced genomes of two strains, ATCC25644 (human isolate) and ATCC27782 (bovine isolate), but only the latter strain produced flagella. Comparison of the L. ruminis and L. mali DSM20444T motility loci showed that their genetic content and gene-order were broadly similar, although the L. mali motility locus was interrupted by an 11.8 Kb region encoding rhamnose utilization genes that is absent from the L. ruminis motility locus. Phylogenetic analysis of 39 motile bacteria indicated that Lactobacillus motility genes were most closely related to those of motile carnobacteria and enterococci. Transcriptome analysis revealed that motility genes were transcribed at a significantly higher level in motile L. ruminis ATCC27782 than in non-motile ATCC25644. Flagellin proteins were isolated from L. ruminis ATCC27782 and from three other Lactobacillus species, while recombinant flagellin of aflagellate L. ruminis ATCC25644 was expressed and purified from E. coli. These native and recombinant Lactobacillus flagellins, and also flagellate L. ruminis cells, triggered interleukin-8 production in cultured human intestinal epithelial cells in a manner suppressed by short interfering RNA directed against Toll-Like Receptor 5. This study provides genetic, transcriptomic, phylogenetic and immunological insights into the trait of flagellum-mediated motility in the lactobacilli.This work was supported by a Principal Investigator Award (07/IN.1/B1780) from Science Foundation Ireland to PWOT. BAN was the recipient of an Embark studentship from the Irish Research Council for Science Engineering and Technology. TD and KN were supported by the Alimentary Pharmabiotic Centre, funded by Science Foundation Ireland

Active cancellation of servo-induced noise on stabilized lasers via feedforward

Many precision laser applications require active frequency stabilization. However, such stabilization loops operate by pushing noise to frequencies outside their bandwidth, leading to large "servo bumps" that can have deleterious effects for certain applications. The prevailing approach to filtering this noise is to pass the laser through a high finesse optical cavity, which places constraints on the system design. Here, we propose and demonstrate a different approach where a frequency error signal is derived from a beat note between the laser and the light that passes through the reference cavity. The phase noise derived from this beat note is fed forward to an electro-optic modulator after the laser, carefully accounting for relative delay, for real-time frequency correction. With a Hz-linewidth laser, we show $\gtrsim20$ dB noise suppression at the peak of the servo bump ($\approx250$ kHz), and a noise suppression bandwidth of $\approx5$ MHz -- well beyond the servo bump. By simulating the Rabi dynamics of a two-level atom with our measured data, we demonstrate substantial improvements to the pulse fidelity over a wide range of Rabi frequencies. Our approach offers a simple and versatile method for obtaining a clean spectrum of a narrow linewidth laser, as required in many emerging applications of cold atoms, and is readily compatible with commercial systems that may even include wavelength conversion

Promoting the Peer-Related Social Development of Young Children With Mild Developmental Delays: Effectiveness of a Comprehensive Intervention

To address the unusual peer-related social competence difficulties characteristic of young children with mild developmental delays, we conducted a randomized clinical trial to evaluate the effectiveness of a comprehensive, developmentally oriented, highly individu-alized intervention extending over a 2-year period. Outcome measures emphasized gener-alization of peer interactions in unfamiliar playgroups. Results revealed modest effects of the intervention, with children who had lower cognitive levels benefiting most. Interven-tion effects were best conceptualized as preventative, minimizing the negative features and atypical patterns of children’s social play with peers. Our discussion of future work was focused on alternative implementation models to enhance intervention intensity, inclusion of specific subgroups of children, and direct measurement of children engaging in social tasks. Extensive observations of preschool-age chil-dren with mild developmental (cognitive) delays in settings involving peers have revealed that sub

First Record of the Southern Red-Backed Vole, Clethrionomys gapperi, in Newfoundland: Implications for the Endangered Newfoundland Marten, Martes americana atrata

We report on the first capture of the Southern Red-backed Vole (Clethrionomys gapperi), the eleventh non-native terrestrial mammal established on the island of Newfoundland over the last 150 years. Red-backed Voles may have been accidentally introduced by unknown sources in pulpwood imports or may have been deliberately introduced in an attempt to augment the depauperate small mammal fauna as a vigilante recovery effort for the endangered Newfoundland Marten (Martes americana atrata). We anticipate significant utilization of the Red-backed Vole as prey by both Newfoundland Marten and Red Fox (Vulpes vulpes) with associated demographic responses within and between these species. Red-backed Voles will likely change habitat utilization patterns for the endemic subspecies of Meadow Vole, Microtus pennsylvanicus terraenovae