Kaplan-Meier curve for renal survival based on histological features of MCGN.

<p>(A) shows differences in outcome between Black Africans and non-Black Africans (log rank p = 0.009); (B) shows gender differences in outcome (log rank p = 0.995); (C) differences between patients who received treatment with cyclophosphamide and those who didn't receive treatment (log rank p = 0.440) and (D) shows differences in outcomes based on the presence of interstitial fibrosis in the biopsy (log rank p = 0.028).</p

Comparison of clinical and histological factors associated with outcome.

<p>SBP – Systolic blood pressure, DBP – Diastolic blood pressure, Ig – Immunoglobulin, C3 – Complement 3.</p><p>Comparison of clinical and histological factors associated with outcome.</p

Kaplan-Meier curve for overall renal survival in the study population.

<p>Kaplan-Meier curve for overall renal survival in the study population.</p

Cox univariate regression analysis for predictors of the end-point.

<p>GFR – Glomerular filtration rate; SBP – systolic blood pressure; DBP – diastolic blood pressure; CR – complete remission, PR – partial remission.</p><p>Cox univariate regression analysis for predictors of the end-point.</p

Demographic, clinical and biochemical features of all the patients.

<p>SBP – Systolic blood pressure, DBP – Diastolic blood pressure, AKI – Acute kidney injury, MDRD – Modification of diet in renal failure, GFR – Glomerular filtration rate.</p><p>Demographic, clinical and biochemical features of all the patients.</p

Histological features of the renal biopsies (n = 79).

<p>Ig – Immunoglobulin, C3 – Complement 3.</p><p>Histological features of the renal biopsies (n = 79).</p

Comparison of biochemical and treatment factors associated with outcome.

<p>MDRD – Modification of Diet in Renal Disease; GFR – Glomerular filtration rate; ACE-I – Angiotensin converting enzyme inhibitors; ARB – Angiotensin receptor blockers.</p><p>Comparison of biochemical and treatment factors associated with outcome.</p

Comparison of Western Cape Guidelines (2010) with the Department of Health Guidelines (2009).

<p>Comparison of Western Cape Guidelines (2010) with the Department of Health Guidelines (2009).</p

Characteristics of Patients assessed by the renal replacement committee before and after the use of Prioritization Criteria (N = 564).

<p>Characteristics of Patients assessed by the renal replacement committee before and after the use of Prioritization Criteria (N = 564).</p

Baseline demographics of Blacks vs. Non-Blacks⁺ among new patients presented to the renal assessment committee in Groote Schuur from 2008–2012.

<p>Baseline demographics of Blacks vs. Non-Blacks<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0176041#t002fn003" target="_blank">⁺</a> among new patients presented to the renal assessment committee in Groote Schuur from 2008–2012.</p