Ribonucleases 1 of ruminants

Mammalian ribonucleases I form a group of homologous proteins.They are pyrimidine specific and cleave RNA endonucleolyticallyto yield 3' phosphomono nucleotidesand oligonucleotides via 2',3' cyclic intermediates. Three homologous ribonucleases were found in ox, pancreaticRNase, seminal RNase and brain RNase. Bovine pancreaticRNase(RNaseA) consists of a single polypeptidechain of 124 anino acids, containing four disulfide bridges. Only a fraction of the secreted amount of enzyme is N-linked glycosylatedatposition34. .... Zie: Summary...

Introduction

An introduction to this issue of Northwestern Review

Introduction

An introduction to this issue of Northwestern Review