Clinical longevity of intracoronal restorations made of gold, lithium disilicate, leucite, and indirect resin composite:a systematic review and meta-analysis

OBJECTIVES: The aim of this systematic review and meta-analysis is to assess the comparative clinical success and survival of intracoronal indirect restorations using gold, lithium disilicate, leucite, and indirect composite materials.MATERIAL AND METHODS: This systematic review and meta-analysis were conducted following the Cochrane Handbook for Systematic Reviews of Interventions and PRISMA guidelines. The protocol for this study was registered in PROSPERO (registration number: CRD42021233185). A comprehensive literature search was conducted across various databases and sources, including PubMed/Medline, Embase, Cochrane Library, Web of Science, ClinicalTrials.gov, and gray literature. A total of 7826 articles were screened on title and abstract. Articles were not excluded based on the vitality of teeth, the language of the study, or the observation period. The risk difference was utilized for the analyses, and a random-effects model was applied. All analyses were conducted with a 95% confidence interval (95% CI). The calculated risk differences were derived from the combined data on restoration survival and failures obtained from each individual article. The presence of heterogeneity was assessed using the I2 statistic, and if present, the heterogeneity of the data in the articles was evaluated using the non-parametric chi-squared statistic (p &lt; 0.05).RESULTS: A total of 12 eligible studies were selected, which included 946 restorations evaluated over a minimum observation period of 1 year and a maximum observation period of 7 years. Results of the meta-analysis indicated that intracoronal indirect resin composite restorations have an 18% higher rate of failure when compared to intracoronal gold restorations over 5-7 years of clinical service (risk difference =  - 0.18 [95% CI: - 0.27, - 0.09]; p = .0002; I2 = 0%). The meta-analysis examining the disparity in survival rates between intracoronal gold and leucite restorations could not be carried out due to methodological differences in the studies.CONCLUSIONS: According to the currently available evidence, medium-quality data indicates that lithium disilicate and indirect composite materials demonstrate comparable survival rates in short-term follow-up. Furthermore, intracoronal gold restorations showed significantly higher survival rates, making them a preferred option over intracoronal indirect resin-composite restorations. Besides that, the analysis revealed no statistically significant difference in survival rates between leucite and indirect composite restorations. The short observation period, limited number of eligible articles, and low sample size of the included studies were significant limitations.CLINICAL SIGNIFICANCE: Bearing in mind the limitations of the reviewed literature, this systematic review and meta-analysis help clinicians make evidence-based decisions on how to restore biomechanically compromised posterior teeth.</p

Women with anorexia nervosa and bulimia nervosa : Individual and family characteristics, with particular emphasis on perfectionism

This study investigated socio-cultural, family and individual factors associated with anorexia and bulimia nervosa, with particular emphasis on dysfunctional perfectionism, and adopting a general social learning perspective. Theories of the development of eating disorders were interwoven with theories of the development of perfectionism. A model was proposed for the development of anorexia and bulimia nervosa via a dysfunctional perfectionism pathway. The 135 participants, aged 18 to 40 years, were women with anorexia nervosa (N=25), bulimia nervosa (N=32), Type 1 diabetes (N= 53, a North Canterbury population-based sample), and healthy women students (N=25). The women with eating disorders were recruited from various treatment centres throughout New Zealand. Participants completed a battery of seven self-report psychometric tests, namely, the Eating Disorder Inventory-2 (EDI-2), Beck Depression Inventory (BDI), Multidimensional Perfectionism Scale (MPS), Setting Conditions for Anorexia Nervosa Scale (SCANS), Tridimensional Personality Questionnaire (TPQ), Parental Bonding Instrument (PBI), and Family Environment Scale (FES). Analysis of Covariance, using the BDI as a covariate, revealed that, in addition to measures concerned with weight, shape and dieting, both anorexia and bulimia nervosa group means were significantly higher than both healthy and diabetes group means for EDI-2 Interpersonal Distrust and Social Insecurity; MPS Concern over Mistakes, Personal Standards, and Parental Criticism; and TPQ Harm A voidance, and significantly different from the healthy group mean for MPS Parental Expectations; SCANS Perfectionism; and PBI Maternal Protection, Maternal Care, and Paternal Care. Correlational analyses confirmed hypothesized moderate or strong associations between some perfectionism measures and other characteristics of women with eating disorders, such as a harm-avoidant temperament, and perceptions of maternal overprotection. Discriminant function analysis revealed seven variables, in combination, that maximally discriminated between eating disordered and non-eating disordered groups: three EDI-2 variables of Drive for Thinness, Ineffectiveness, and Social Insecurity, three MPS subscales of Concern over Mistakes, Personal Standards, and Doubts about Actions, and the BDI. Of the three instruments measuring perfectionism, in this study, only the MPS effectively discriminated between eating disordered and non-eating disordered groups. Findings indicated the importance of controlling for depression when comparing eating disordered groups with other groups, and that dysfunctional perfectionism is largely independent of the mood of the respondent. Findings suggest that the PBI may be limited by cultural sensitivity. Findings led to questioning of the applicability of the EDI-SC to diabetes groups and of the validity of the Novelty Seeking and Reward Dependence Dimensions of the TPQ. In concluding that dysfunctional perfectionism is a key personality characteristic of women with anorexia and bulimia nervosa, it is argued that multidimensional measures of perfectionism provide more insight than unidimensional measures into the dysfunctional facets of perfectionism, and that perfectionism per se is not necessarily problematic. Dysfunctional perfectionism may distinguish psychopathology associated with anorexia and bulimia nervosa from numerous other forms of psychopathology, including depression. Although aetiological factors were not assessed in this study, the MPS and PBI, considered in conjunction with the theoretical literature, may provide insight into the development of dysfunctional perfectionism. This has implications for the treatment and prevention of eating disorders

Noncommutative Geometry of Finite Groups

A finite set can be supplied with a group structure which can then be used to select (classes of) differential calculi on it via the notions of left-, right- and bicovariance. A corresponding framework has been developed by Woronowicz, more generally for Hopf algebras including quantum groups. A differential calculus is regarded as the most basic structure needed for the introduction of further geometric notions like linear connections and, moreover, for the formulation of field theories and dynamics on finite sets. Associated with each bicovariant first order differential calculus on a finite group is a braid operator which plays an important role for the construction of distinguished geometric structures. For a covariant calculus, there are notions of invariance for linear connections and tensors. All these concepts are explored for finite groups and illustrated with examples. Some results are formulated more generally for arbitrary associative (Hopf) algebras. In particular, the problem of extension of a connection on a bimodule (over an associative algebra) to tensor products is investigated, leading to the class of `extensible connections'. It is shown that invariance properties of an extensible connection on a bimodule over a Hopf algebra are carried over to the extension. Furthermore, an invariance property of a connection is also shared by a `dual connection' which exists on the dual bimodule (as defined in this work).Comment: 34 pages, Late

Noncommutative geometry and physics: a review of selected recent results

This review is based on two lectures given at the 2000 TMR school in Torino. We discuss two main themes: i) Moyal-type deformations of gauge theories, as emerging from M-theory and open string theories, and ii) the noncommutative geometry of finite groups, with the explicit example of Z_2, and its application to Kaluza-Klein gauge theories on discrete internal spaces.Comment: Based on lectures given at the TMR School on contemporary string theory and brane physics, Jan 26- Feb 2, 2000, Torino, Italy. To be published in Class. Quant. Grav. 17 (2000). 3 ref.s added, typos corrected, formula on exterior product of n left-invariant one-forms corrected, small changes in the Sect. on integratio

Duration of right ventricular contraction predicts the efficacy of bosentan treatment in patients with pulmonary hypertension

AIMS: In patients with pulmonary hypertension (PH), elevated endothelin-1 levels are associated with prolonged duration of right ventricular (RV) contraction, which induces leftward ventricular septal bowing with impaired left diastolic filling. We hypothesized that baseline RV contraction duration predicts efficacy of endothelin receptor antagonist, bosentan.METHODS AND RESULTS: Eighteen PH patients (age 57, range 35-79 years, 33% male) received bosentan. Six minute walk distance (6-MWD) and echocardiography were performed at baseline and after 1 year follow-up. After 1 year of treatment, 6-MWD increased (mean 60 +/- 41 m) in 67% of patients (responders). Baseline RV contraction duration was longer in responders, compared with non-responders (612 +/- 66 vs. 514 +/- 23 ms; P &lt; 0.01). A baseline RV contraction duration &gt;550 ms was associated with improved 6-MWD (sensitivity 83%, specificity 83%; P &lt; 0.01).CONCLUSION: An improvement of 6-MWD during bosentan treatment was associated with a decrease in RV contraction duration and could be predicted by a baseline RV contraction duration &gt;550 ms.</p

Demostración de resultado económico: percepción del comando da aeronáutica de Brasil

No ano de 2010, uma alteração no quadro normativo brasileiro introduziu a Demonstração do Resultado Econômico (DRE) para o setor público, que busca comparar custos internos de produção com valores de mercado, segundo o conceito de custo de oportunidade. Este estudo procura analisar as possíveis respostas estratégicas dos gestores , buscando perceber se a cultura contábil existente no País permite a aceitação do novo instrumento. Por meio das percepções dos agentes públicos do Comando da Aeronáutica (Comaer), no Brasil, conclui-se que a resposta estratégica dos entrevistados tende para a atitude de aceitação da nova rotina, demonstrando traços de menor conservadorismo e maior interesse pela evidenciação de resultados.In 2010, a change in the Brazilian accounting regulatory framework introduced the Demonstração do Resultado Econômico (DRE) [Economic Income Statement] for the public sector, which seeks to compare the internal costs of production to market values, according to the concept of opportunity cost. This study aims to analyse the possible strategic responses of managers and tries to understand if the existing accounting culture in Brazil facilitates the introduction of the new statement. By means of perceptions of officials of the Aeronautical Command (Comaer), in Brazil, it is possible to conclude that the strategic response of respondents is closer to acceptance of the new routine, showing traces of less conservatism and greater interest for displaying results.En el año 2010, una modificación del cuadro normativo brasileño introdujo la Demostración del Resultado Económico (DRE) para el sector público, que busca comparar los costos internos de producción con los valores del mercado, según el concepto de costo de oportunidad. Este estudio tiene como objetivo analizar las posibles respuestas estratégicas de los gestores, con el fin de percibir si la cultura contable existente en el país permite la aceptación del nuevo instrumento. Por medio de las percepciones de los agentes públicos del Comando da Aeronáutica (Comaer), en Brasil, se concluyó que la respuesta estratégica de los entrevistados tiende a aceptar la nueva rutina, mostrando rasgos de menos conservadurismo y más interés por la manifestación de resultados.Fundação para a Ciência e a Tecnologia (FCT