Additional file 1: Supplementary data on the synthesis of BODIPY-BBN, its in-vitro characterization and its in-vivo biodistribution and stability. Figure S1. of Development of a clickable bimodal fluorescent/PET probe for in vivo imaging

Synthesis and analytical data of BODIPY-azide 1. Figure S2. Synthesis of BODIPY-BBN 5 using CuAAC click chemistry. Figure S3. In vitro cell binding study of BODIPY-BBN 5 using GRPr overexpressing PC-3 cells. Figure S4. Quantification of tumor uptake comparing fluorescent imaging as well as gamma-counting. Figure S5. In vivo small animal PET/CT images (60 min) of PC-3 tumor-bearing nude mice after intravenous injection of 18F-BODIPY-BBN 3 (55 ± 10 μCi) in PBS (4 % DMSO, 200 μL). Figure S6. Percent intact fluorescent 19F-BODIPY-BBN in human serum at different time points (0, 15, 30, 45, and 60 min) after incubation at 37 °C

Additional file 1: of Discriminating radiation injury from recurrent tumor with [18F]PARPi and amino acid PET in mouse models

Figures S1–S9 and Tables S1–S6. (PDF 14174 kb