Regular string-like braneworlds

In this work, we propose a new class of smooth thick string-like braneworld in six dimensions. The brane exhibits a varying brane-tension and an $AdS$ asymptotic behavior. The brane-core geometry is parametrized by the Bulk cosmological constant, the brane width and by a geometrical deformation parameter. The source satisfies the dominant energy condition for the undeformed solution and has an exotic asymptotic regime for the deformed solution. This scenario provides a normalized massless Kaluza-Klein mode for the scalar, gravitational and gauge sectors. The near-brane geometry allows massive resonant modes at the brane for the $s$ state and nearby the brane for $l=1$.Comment: 14 pages, 12 figures. Some modifications to match the published version in EPJ

Yield of cotton cultivars under different irrigation depths in the Brazilian semi-arid region.

The objective of this study was to evaluate the effect of irrigation depths on seed cotton yield and water-use efficiency of cotton cultivars in the Brazilian semi-arid region. Field experiment was conducted during two consecutive years in the Apodi region, RN, using sprinkler irrigation. The experiment consisted of factorial combination in split-plots, composed of four irrigation depths (130; 100; 70 and 40% ETc and four cotton cultivars - FiberMax 993, BRS 286, BRS 336 and BRS 335), in randomized block design with 4 replicates. Data were evaluated by mean test (Tukey) and regression analysis. Considering the irrigation depths of 40% ETc, cotton yield was 48% lower compared to the higher irrigation depth (130% ETc). The higher water-use efficiency (0.69 kg m-3) was obtained with 70% ETc irrigation depth. The highest seed cotton yield was achieved with the higher water depth for all evaluated cultivars. Yield response factor (Ky) was equal to 0.632, 0.711, 0.784 and 0.858, for FiberMax 993, BRS 286, BRS 335 and BRS 336 cultivars, respectively. FiberMax 993 and BRS 286 cultivars presented the best performance, showing that they are more suitable for irrigated farming in the semi-arid region

Probing Yukawian gravitational potential by numerical simulations. I. Changing N-body codes

In the weak field limit general relativity reduces, as is well known, to the Newtonian gravitation. Alternative theories of gravity, however, do not necessarily reduce to Newtonian gravitation; some of them, for example, reduce to Yukawa-like potentials instead of the Newtonian potential. Since the Newtonian gravitation is largely used to model with success the structures of the universe, such as for example galaxies and clusters of galaxies, a way to probe and constrain alternative theories, in the weak field limit, is to apply them to model the structures of the universe. In the present study, we consider how to probe Yukawa-like potentials using N-body numerical simulations.Comment: 17 pages, 11 figures. To appear in General Relativity and Gravitatio

IL18 gene polymorphism and its influence on CD4+ T-cell recovery in HIV-positive patients receiving antiretroviral therapy

Background: Pyroptosis has been reported to be critical in human immunodeficiency virus type 1 (HIV-1) pathogenesis and acquired immunodeficiency syndrome (AIDS) progression. Even after achieving viral suppression to undetectable levels during antiretroviral therapy (ART), exacerbated CD4+ T-cell death by pyroptosis has been suggested as one of the main causes of immunological non-response. Thus, variants in genes of pyroptosis pathway were studied in individuals with poor CD4+ T-cell reconstitution under antiretroviral therapy against HIV-1. Methods: 248 virologically suppressed ART-treated patients, 126 immunological non-responders (INR) and 122 immunological responders (IR) were recruited. Genotyping was performed using TaqMan probe-based realtime PCR platform. Genotype-guided flow cytometry analysis with general and recent thymic emigrant (RTE) CD4+ T-cells in pyroptosis was performed based on associated polymorphisms. Results: Both IL18 rs187238 G allele and GG genotype were associated as protection factors against poor CD4+ T-cell recovery (OR = 0.22; 95%CI = 0.50\u20130.77; P =.010 and OR = 0.58; 95%CI = 0.36\u20130.93; P =.022, respectively). It was demonstrated a statistical association between IL18 rs187238 genotypes of ART-treated patients and death by Caspase-1 levels (P =.020). The GG genotype showed lower pyroptotic RTE CD4+ T-lymphocytes levels in the ART-treated groups comparing with CC (P =.029) and CG (P =.018) genotypes, suggesting that the G allele presence may be related to a lower IL-18 production and thus reduced dead CD4+ T-cells levels by Caspase-1. Conclusion: We observed that IL18 G variant allele and genotype were associated with a better immunological response, which may influence on immunological recovery of HIV-positive patients receiving antiretroviral therapy, and low Caspase-1 activity levels was observed on GG genotype when compared CC genotypes