102 research outputs found
Resolution of inflammation: a new therapeutic frontier
Dysregulated inflammation is a central pathological process in diverse disease states. Traditionally, therapeutic approaches have sought to modulate the pro- or anti-inflammatory limbs of inflammation, with mixed success. However, insight into the pathways by which inflammation is resolved has highlighted novel opportunities to pharmacologically manipulate these processes — a strategy that might represent a complementary (and perhaps even superior) therapeutic approach. This Review discusses the state of the art in the biology of resolution of inflammation, highlighting the opportunities and challenges for translational research in this field
Induction of tolerance to type iii pneumococcal polysaccharide (s3) with s3 coupled to spleen cells. Abstr.
Secondary igg responses to type iii pneumococcal polysaccharide. I. Kinetics and antigen requirements.
Regulatory role of t cells in igg antibody formation and immune memory to type iii pneumococcal polysaccharide.
The role of t cells in the induction of b memory cells: influence of variations in experimental design.
Suppression of the antibody response to type iii pneumococcal polysaccharide with antigen coupled to syngeneic lymphoid cells.
Selective suppression of primary igm responses by induction of low dose paralysis to type iii pneumococcal polysaccharide.
Secondary igg responses to type iii pneumococcal polysaccharide. II. Different cellular requirements for induction and elicitation.
Antigen requirement for induction of b-memory cells. Studies with dinitrophenyl coupled to t-dependent and t-independent carriers.
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