IMPORTÂNCIA DA AVALIAÇÃO CLÍNICA NO DIAGNÓSTICO DE DOENÇA PERIODONTAL EM CÃES DA RAÇA PASTOR ALEMÃO

As doenças periodontais resultam de resposta inflamatória progressiva do hospedeiro ao acúmulo de placa bacteriana, incluindo os metabólitos no dente e nos tecidos gengivais. Assim, avaliou-se, clinicamente, o periodonto de cães da raça Pastor Alemão, levando-se em consideração presença de tártaro, sangramento à sondagem e mobilidade dentária em animais com sítios saudáveis e com doença periodontal. Para isso, utilizaram-se 29 cães,da raça Pastor Alemão, com idade variando de três a seis anos. Clinicamente, 27 (93,10%) cães apresentavam vários sítios com sintomatologia clínica de doença periodontal e somente dois apresentavam sítios saudáveis. Os dentes mais acometidos foram os molares, os pré-molares e os caninos,com sinais clínicos mais intensos nas superfícies dentárias e maior acúmulo de tártaro e placa bacteriana. Os resultados demonstraram a necessidade de se proceder a uma limpeza preventiva dos dentes, para proporcionar maior saúde para os cães.
 PALAVRAS-CHAVE: Periodonto, cães, dente

POISONING OF WILDLIFE IN ENVIRONMENAL PARKS OF BRAZIL

The city of Anapolis located in the state of Goiás, Brazil, has several environmental parks that serve as habitat and refuge for many wild animals. The parks represent the last refuge for some wild animals such asmarmoset, possum, armadillo, capuchin monkey, owl, lapwing, among others. In addition, the parks play an important role for climate mitigation and preservation of the ecosystem, and represent an important recreational area for residents. Recently, mortality rates have increased in non-human primates, including capuchin monkeys and marmosets,as well as skunks from environmental parks as Ipiranga, Matinha, and Central Park. Based on history and clinical signs - rapid onset, tetanic seizures and pupils dilated -strychnine poisoning was suspected. Necropsies were done in 15 marmosets (Callithrix penicillata). Of a total of 13marmosets from Central Park, nine showed petechiae in the pancreas, and presence of green strychnine-laced grain in the digestive tract.However, marmosets from Matinha and Ipiranga parks showed no specific necropsy lesions. Conducting monitoring of the Central Park showed that it undergoes reform. The hypothesis was that the employees were poisoning the marmosets since the animals constantly stole employees’ meals. Thus, an environmental education program was held in all three parks of the city. Employees and visitors of the parks were instructed about importanceofwildlifeconservation and biodiversity maintenance.A positive result was obtained after education program since no more animal deathshave beenobserved in the parks

PREVALENCE OF HELICOBACTER PYLORI INFECTION IN DYSPEPTIC PATIENTS AND ITS ASSOCIATION WITH CLINICAL RISK FACTORS FOR DEVELOPING GASTRIC ADENOCARCINOMA

ABSTRACT BACKGROUND: In Brazil, particularly in the underdeveloped localities, the prevalence of Helicobacter pylori (H. pylori) infections can range up to 90%. These rates are higher in older individuals and vary by country region. H. pylori infections are linked to the development of gastric pathologies, namely mild to moderate gastritis, gastroenteritis, peptic ulcer, intestinal metaplasia, and gastric cancer. In 1994, this organism was classified by the International Agency for Research on Cancer (IARC) as pertaining to the Group 1 carcinogen for gastric adenocarcinoma etiology. Gastric cancer represents a significant public health problem, being the fourth most common malignant tumor and the second largest cause of cancer-related deaths. OBJECTIVE: To investigate the prevalence of H. pylori infection in dyspeptic patients and determine the link between clinical risk factors and gastric adenocarcinoma diagnosis. METHODS: Polymerase chain reaction (PCR) analysis was employed for molecular diagnosis of gastric tissue biopsies collected from 113 dyspeptic patients at the University Hospital of Federal University of Goiás. Molecular analyses allowed the identification of H. pylori infections. Furthermore, histopathological examinations were performed to determine the clinical risks of developing gastric malignancies. RESULTS: The test results identified 69 individuals older than 44 years, from 75 (66.4%) positive H. pylori infection samples. The prevalence of gastric adenocarcinoma in this study was 1.3%. Among the infected patients, six (8.2%) had high risk, and 67 (91.8%) had a low risk of developing gastric cancer (P<0.05). CONCLUSION: This study shows a high prevalence of H. pylori infection and identifies its contribution to gastric inflammations, which in the long term are manifested in high-risk clinical factors for the development of gastric adenocarcinoma

Isolamento e identificação da microbiota periodontal de cães da raça Pastor Alemão Isolate and identify of periodontal microbiota of German Shepherd dogs

A microbiota indígena gengival de cães não está totalmente descrita, sendo sua identificação uma etapa importante no estabelecimento da etiopatogenia e terapia da doença periodontal. O objetivo deste trabalho foi isolar e identificar a microbiota periodontal de cães da raça Pastor Alemão, considerando sítios saudáveis e com doença periodontal. Foram utilizados 29 cães, com idade variando de três a seis anos, sendo analisados espécimes clínicos de sítios periodontais saudáveis de 12 cães e sítios com periodontite de outros 17. Foram isoladas 672 amostras microbianas, com predomínio dos gêneros Pasteurella, Staphylococcus, Porphyromonas e Fusobacterium. A microbiota dos sítios saudáveis equiparou-se à dos sítios doentes, tratando-se de uma microbiota indígena. A microbiota dos sítios doentes apresentou-se aumentada em relação a dos sítios saudáveis, indicando mudança do ambiente do sítio periodontal.<br>The indigenous gingival microbiota of dogs is not totally described, although such identification is an important step to establish the etiopathogenesis and adequate therapy for the periodontal disease. The aims of this study were to isolate and identify the periodontal microbiota of German Shepherd dogs from healthy and with periodontal desease sites. Twenty nine German Shepherd dogs from three to six years of age were used in this study. Clinical specimens were analysed from healthy periodontal sites of 12 dogs and sites presenting gingivitis of 17 dogs. A total amount of 672 microbial samples, were isolated where the predominant genera were Pasteurella spp., Staphylococcus spp., Porphyromonas spp. and Fusobacterium spp. The microbiological population of the affected sites was similar to the healthy sites, consisting on an indigenous microbiota. The microbiota on the affecteded sites was higher in number than on the healthy sites, showing change in the environment of the periodontal sites