NTFP commercialisation in Zimbabwe

A study of the woodcraft sector in Zimbabwe was conducted to understand the potential role of NTFP commercialisation in rural households. Zimbabwe experienced an uosurge in the marketing of wodcarvings and other craft articles during the 1990s. Possible social and ecological impacts originating from this informal commerce have alarmed environmentalists, governmental and non-governmental intitutions, and policy makers. Up to the time of the study no clear policy on the woodcarving sector was apparent, with some institutions promoting it as means to improving income, while other intitutions were involved in trying to halt the sector, using the current legislation to guide their actions

Reaktionskinetik in Glasschmelzen Experiment ES 307 Frischat in der 1. Spacelabmission (FSLP)

TIB: AC 9101 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Reaktionskinetik in Glasschmelzen - Korrosion von SiO2 Projekt TEXUS IV

TIB: AC 6871 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Vitamin C: A Natural Inhibitor of Cell Wall Functions and Stress Response in Mycobacteria

Tuberculosis, caused by Mycobacterium tuberculosis, has re-emerged as a threat to human race. Conventional antibiotic treatments are failing due to different stress response strategies adopted by bacterial pathogens. Since time immemorial, Vitamin C is known to protect against pathogens by boosting immunity in humans. Recently, Vitamin C has been shown to directly kill M. tuberculosis including multiple drug-resistant strains by generation of oxidative radicals through Fenton's reaction. Concurrently, it inhibits (p) ppGpp-mediated stringent response thus effectively shutting down long-term survival and persistence in mycobacteria. Here, we have discussed historical perspective and recent evidences on Vitamin C-mediated inhibition of several key pathways of M. tuberculosis such as (p) ppGpp synthesis and mycobacterial cell wall function. Several cell wall components including mycolic acids are critical for mycobacterial virulence. We observed downregulation of various mycolic acids in M. smegmatis upon treatment with Vitamin C, and data have been presented here. Vitamin C has been shown to inhibit the biofilm growth as well as disrupt the formed biofilm in mycobacteria. Additionally, Vitamin C role in cell-mediated and humoral immunity has been elucidated. Vitamin C is toxic at high concentration; therefore we have proposed the idea of derivatizing Vitamin C in order to lower the minimal inhibition concentration (MIC) necessary to target M. tuberculosis