112 research outputs found
The dynamics of vortex generation in superfluid 3He-B
A profound change occurs in the stability of quantized vortices in externally
applied flow of superfluid 3He-B at temperatures ~ 0.6 Tc, owing to the rapidly
decreasing damping in vortex motion with decreasing temperature. At low damping
an evolving vortex may become unstable and generate a new independent vortex
loop. This single-vortex instability is the generic precursor to turbulence. We
investigate the instability with non-invasive NMR measurements on a rotating
cylindrical sample in the intermediate temperature regime (0.3 - 0.6) Tc. From
comparisons with numerical calculations we interpret that the instability
occurs at the container wall, when the vortex end moves along the wall in
applied flow.Comment: revised & extended version. Journal of Low Temperature Physics,
accepted (2008
Probing Bogoliubov Quasiparticles in Superfluid 3He with a âVibrating-Wire Likeâ MEMS Device
International audienceWe have measured the interaction between superfluid 3 He-B and a micro-machined goalpost-shaped device at temperatures below 0.2 T c. The measured damping follows well the theory developed for vibrating wires, in which the An-dreev reflection of quasiparticles in the flow field around the moving structure leads to a nonlinear frictional force. At low velocities the damping force is proportional to velocity while it tends to saturate for larger excitations. Above a velocity of 2.6 mms â1 the damping abruptly increases, which is interpreted in terms of Cooper-pair breaking. Interestingly, this critical velocity is significantly lower than reported with other mechanical probes immersed in superfluid 3 He. Furthermore , we report on a nonlinear resonance shape for large motion amplitudes that we interpret as an inertial effect due to quasiparticle friction, but other mechanisms could possibly be invoked as well. PACS numbers: 85.85.+j, 67.30.H-, 67.30.e
Tree method for quantum vortex dynamics
We present a numerical method to compute the evolution of vortex filaments in
superfluid helium. The method is based on a tree algorithm which considerably
speeds up the calculation of Biot-Savart integrals. We show that the
computational cost scales as Nlog{(N) rather than N squared, where is the
number of discretization points. We test the method and its properties for a
variety of vortex configurations, ranging from simple vortex rings to a
counterflow vortex tangle, and compare results against the Local Induction
Approximation and the exact Biot-Savart law.Comment: 12 pages, 10 figure
Thermal Detection of Turbulent and Laminar Dissipation in Vortex Front Motion
We report on direct measurements of the energy dissipated in the spin-up of
the superfluid component of 3He-B. A vortex-free sample is prepared in a
cylindrical container, where the normal component rotates at constant angular
velocity. At a temperature of 0.20Tc, seed vortices are injected into the
system using the shear-flow instability at the interface between 3He-B and
3He-A. These vortices interact and create a turbulent burst, which sets a
propagating vortex front into motion. In the following process, the free energy
stored in the initial vortex-free state is dissipated leading to the emission
of thermal excitations, which we observe with a bolometric measurement. We find
that the turbulent front contains less than the equilibrium number of vortices
and that the superfluid behind the front is partially decoupled from the
reference frame of the container. The final equilibrium state is approached in
the form of a slow laminar spin-up as demonstrated by the slowly decaying tail
of the thermal signal.Comment: 12 pages, 5 figures, to appear in Journal of Low Temperature Physic
The sensitivity of the vortex filament method to different reconnection models
We present a detailed analysis on the effect of using different algorithms to
model the reconnection of vortices in quantum turbulence, using the
thin-filament approach. We examine differences between four main algorithms for
the case of turbulence driven by a counterflow. In calculating the velocity
field we use both the local induction approximation (LIA) and the full
Biot-Savart integral. We show that results of Biot-Savart simulations are not
sensitive to the particular reconnection method used, but LIA results are.Comment: 9 pages, 9 figure
Indications and outcomes of enucleation versus formal pancreatectomy for pancreatic neuroendocrine tumors
Background: Pancreatoduodenectomy (PD) or distal pancreatectomy (DP) are common procedures for patients with a pancreatic neuroendocrine tumor (pNET). Nevertheless, certain patients may benefit from a pancreas-preserving resection such as enucleation (EN). The aim of this study was to define the indications and differences in long-term outcomes among patients undergoing EN and PD/DP. Methods: Patients undergoing resection of a pNET between 1992 and 2016 were identified. Indications and outcomes were evaluated, and propensity score matching (PSM) analysis was performed to compare long-term outcomes between patients who underwent EN versus PD/DP. Results: Among 1034 patients, 143 (13.8%) underwent EN, 304 (29.4%) PD, and 587 (56.8%) DP. Indications for EN were small size (1.5 cm, IQR:1.0â1.9), functional tumors (58.0%) that were mainly insulinomas (51.7%). After PSM (n = 109 per group), incidence of postoperative pancreatic fistula (POPF) grade B/C was higher after EN (24.5%) compared with PD/DP (14.0%) (p = 0.049). Median recurrence-free survival (RFS) was comparable among patients who underwent EN (47 months, 95% CI:23â71) versus PD/DP (37 months, 95% CI: 33â47, p = 0.480). Conclusion: Comparable long-term outcomes were noted among patients who underwent EN versus PD/DP for pNET. The incidence of clinically significant POPF was higher after EN
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
Structural variation (SV) represents a major source of differences between individual human genomes and has been linked to disease phenotypes. However, the majority of studies provide neither a global view of the full spectrum of these variants nor integrate them into reference panels of genetic variation. Here, we analyse whole genome sequencing data of 769 individuals from 250 Dutch families, and provide a haplotype-resolved map of 1.9 million genome variants across 9 different variant classes, including novel forms of complex indels, and retrotransposition-mediated insertions of mobile elements and processed RNAs. A large proportion are previously under reported variants sized between 21 and 100 bp. We detect 4 megabases of novel sequence, encoding 11 new transcripts. Finally, we show 191 known, trait-associated SNPs to be in strong linkage disequilibrium with SVs and demonstrate that our panel facilitates accurate imputation of SVs in unrelated individuals
Brain volumetric deficits in MAPT mutation carriers: a multisite study
Objective: MAPT mutations typically cause behavioral variant frontotemporal dementia with or without parkinsonism. Previous studies have shown that symptomatic MAPT mutation carriers have frontotemporal atrophy, yet studies have shown mixed results as to whether presymptomatic carriers have low gray matter volumes. To elucidate whether presymptomatic carriers have lower structural brain volumes within regions atrophied during the symptomatic phase, we studied a large cohort of MAPT mutation carriers using a voxelwise approach. Methods: We studied 22 symptomatic carriers (age 54.7 ± 9.1, 13 female) and 43 presymptomatic carriers (age 39.2 ± 10.4, 21 female). Symptomatic carriersâ clinical syndromes included: behavioral variant frontotemporal dementia (18), an amnestic dementia syndrome (2), Parkinsonâs disease (1), and mild cognitive impairment (1). We performed voxel-based morphometry on T1 images and assessed brain volumetrics by clinical subgroup, age, and mutation subtype. Results: Symptomatic carriers showed gray matter atrophy in bilateral frontotemporal cortex, insula, and striatum, and white matter atrophy in bilateral corpus callosum and uncinate fasciculus. Approximately 20% of presymptomatic carriers had low gray matter volumes in bilateral hippocampus, amygdala, and lateral temporal cortex. Within these regions, low gray matter volume
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