8 research outputs found

    Synthesis of Tricyclic Analogues of Stephaoxocanidine and Their Evaluation as Acetylcholinesterase Inhibitors.

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    Schmeda-Hirschmann, G. Laboratorio de Quımica de Productos Naturales, Instituto de Quımica de Recursos Naturales, Universidad de Talca, Casilla 747, Talca, Chile.Theoduloz C. Facultad de Ciencias de la Salud, Laboratorio de Cultivo Celular, Universidad de Talca, Casilla 747, Talca, ChileThe synthesis of simplified analogs of the novel isoquinoline alkaloid stephaoxocanidine, carrying the oxazaphenalene ABC-ring system of the natural product, and their activity as inhibitors of the enzyme acetylcholinesterase, are reported. 5,6-Dimethoxy-7H-8-oxa-1-aza-phenalen-9-one (5) was as active as a Narcissus extract enriched in galantamine

    Medicinal plants as a source of alkaloids

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    Gold(I)-Catalyzed Tandem Reactions Initiated by Hydroamination of Alkynyl Carbamates: Application to the Synthesis of Nitidine

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    Chemicals from Hemicelluloses: A Review

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