26 research outputs found

    Boosting Few-shot Action Recognition with Graph-guided Hybrid Matching

    Full text link
    Class prototype construction and matching are core aspects of few-shot action recognition. Previous methods mainly focus on designing spatiotemporal relation modeling modules or complex temporal alignment algorithms. Despite the promising results, they ignored the value of class prototype construction and matching, leading to unsatisfactory performance in recognizing similar categories in every task. In this paper, we propose GgHM, a new framework with Graph-guided Hybrid Matching. Concretely, we learn task-oriented features by the guidance of a graph neural network during class prototype construction, optimizing the intra- and inter-class feature correlation explicitly. Next, we design a hybrid matching strategy, combining frame-level and tuple-level matching to classify videos with multivariate styles. We additionally propose a learnable dense temporal modeling module to enhance the video feature temporal representation to build a more solid foundation for the matching process. GgHM shows consistent improvements over other challenging baselines on several few-shot datasets, demonstrating the effectiveness of our method. The code will be publicly available at https://github.com/jiazheng-xing/GgHM.Comment: Accepted by ICCV202

    Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

    Get PDF
    We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese individuals and performed further transancestry meta-analyses with data from the Psychiatry Genomics Consortium (PGC2). Approximately 95% of the genome-wide significant (GWS) index alleles (or their proxies) from the PGC2 study were overrepresented in Chinese schizophrenia cases, including ∌50% that achieved nominal significance and ∌75% that continued to be GWS in the transancestry analysis. The Chinese-only analysis identified seven GWS loci; three of these also were GWS in the transancestry analyses, which identified 109 GWS loci, thus yielding a total of 113 GWS loci (30 novel) in at least one of these analyses. We observed improvements in the fine-mapping resolution at many susceptibility loci. Our results provide several lines of evidence supporting candidate genes at many loci and highlight some pathways for further research. Together, our findings provide novel insight into the genetic architecture and biological etiology of schizophrenia

    Addition to “Thianthrenation-Enabled Pyrrolidin-2-yl and Tetrahydrofuran-2-yl Methylation of (Hetero)Arenes”

    No full text
    Addition to “Thianthrenation-Enabled Pyrrolidin-2-yl and Tetrahydrofuran-2-yl Methylation of (Hetero)Arenes

    Microdroplet-Controlled Divergent Reactivity at a Gas-Organic Interface

    No full text
    Gas-liquid Interface plays key roles in many fantastic phenomena due to specific properties. Although remarkable reactivities were benefited from gas-water interface of aqueous microdroplets, it remains unknown for gas-organic interface. This work discovers such extraordinary reactivity of gas-organic interface using organic microdroplets (acetonitrile and other organic solvents). This reactivity at the gas-organic interface facilitated a novel micrordroplet-controlled divergence, i.e., double C–N cleavage in high efficiency (yields > 90% in milliseconds) compared to single C–N bond breakdown and intramolecular cycloarrangement in bulk under harsher conditions from the same imidazolines. This study is not only important to wide applicability and inherent mechanisms of the gas-organic interface but also enables good insights into gas-water and other interface-rich studies in atmospheric and photochemistry, on-water chemistry, biological and biomedical, industrial, and energy

    Breaking 10% Efficiency in Semitransparent Solar Cells with Fused-Undecacyclic Electron Acceptor

    No full text
    A fused-undecacyclic electron acceptor IUIC has been designed, synthesized and applied in organic solar cells (OSCs) and semitransparent organic solar cells (ST-OSCs). In comparison with its counterpart, fused-heptacyclic ITIC4, IUIC with a larger π-conjugation and a stronger electron-donating core exhibits a higher LUMO level (IUIC: −3. 87 eV vs ITIC4: −3.97 eV), 82 nm red-shifted absorption with larger extinction coefficient and smaller optical bandgap, and higher electron mobility. Thus, IUIC-based OSCs show higher values in open-circuit voltage, short-circuit current density, and thereby much higher power conversion efficiency (PCE) than those of the ITIC4-based counterpart. The as-cast OSCs based on PTB7-Th: IUIC without any extra treatment yield PCEs of up to 11.2%, higher than that of the control devices based on PTB7-Th: ITIC4 (8.18%). The as-cast ST-OSCs based on PTB7-Th: IUIC without any extra treatment afford PCEs of up to 10.2% with an average visible transmittance (AVT) of 31%, higher than those of the control devices based on PTB7-Th: ITIC4 (PCE = 6.42%, AVT = 28%)

    Online Digital Holographic Method for Interface Reaction Monitoring in Lithium-Ion Batteries

    No full text
    Understanding the reaction mechanisms at the interface of electrode and electrolyte is both of fundamental interest and essential to improve lithium-ion battery (LIB) performance. Herein, we report an online digital holographic method to in situ observe the entire interface change between electrode and electrolyte in lithium-ions batteries. The accuracy of this technology is well verified in LiFePO<sub>4</sub>/graphite full-cell systems, graphite/Li half-cell systems in EC-based and PC-based electrolyte, respectively, and supported by the characterized results of conventional instruments, including scanning electron microscopy and X-ray photoelectron spectroscopy. In particular, the time resolution of the digital holographic method is 0.04 s and fast enough to distinguish detail reduction process of ethylene carbonate (EC), for which EC will be first reduced to generate lithium alkyl carbonates, and then the reduction product is Li<sub>2</sub>CO<sub>3</sub> to form a stable SEI films. To our best of knowledge, this is the first report on the reduction order of the EC solvent and can act as an effective complement to understanding the formation mechanisms of SEI films

    Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer

    No full text
    <div><p>Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) and the underlying molecular mechanisms are not known. In the present study, during induction of radio- or chemo-resistance in NSCLC cells, dynamic analyses revealed that decreased expression of let-7 induced by irradiation or cisplatin resulted in increased expression of its target gene <i>LIN28</i>, and increased expression of LIN28 then contributed to further decreased expression of let-7 by inhibiting its maturation and biogenesis. Moreover, we showed that down-regulation of let-7 and up-regulation of LIN28 expression promoted resistance to irradiation or cisplatin by regulating the single-cell proliferative capability of NSCLC cells. Consequently, in NSCLC cells, let-7 and LIN28 can form a double-negative feedback loop through mutual inhibition, and disturbance of the let-7/LIN28 double-negative feedback loop induced by irradiation or chemotherapeutic drugs can result in radio- and chemo-resistance. In addition, low expression of let-7 and high expression of LIN28 in NSCLC patients was associated significantly with resistance to radiotherapy or chemotherapy. Therefore, our study demonstrated that disturbance of the let-7/LIN28 double-negative feedback loop is involved in the regulation of radio- and chemo-resistance, and that let-7 and LIN28 could be employed as predictive biomarkers of response to radiotherapy or chemotherapy in NSCLC patients.</p></div
    corecore