26 research outputs found
Boosting Few-shot Action Recognition with Graph-guided Hybrid Matching
Class prototype construction and matching are core aspects of few-shot action
recognition. Previous methods mainly focus on designing spatiotemporal relation
modeling modules or complex temporal alignment algorithms. Despite the
promising results, they ignored the value of class prototype construction and
matching, leading to unsatisfactory performance in recognizing similar
categories in every task. In this paper, we propose GgHM, a new framework with
Graph-guided Hybrid Matching. Concretely, we learn task-oriented features by
the guidance of a graph neural network during class prototype construction,
optimizing the intra- and inter-class feature correlation explicitly. Next, we
design a hybrid matching strategy, combining frame-level and tuple-level
matching to classify videos with multivariate styles. We additionally propose a
learnable dense temporal modeling module to enhance the video feature temporal
representation to build a more solid foundation for the matching process. GgHM
shows consistent improvements over other challenging baselines on several
few-shot datasets, demonstrating the effectiveness of our method. The code will
be publicly available at https://github.com/jiazheng-xing/GgHM.Comment: Accepted by ICCV202
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia
We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese individuals and performed further transancestry meta-analyses with data from the Psychiatry Genomics Consortium (PGC2). Approximately 95% of the genome-wide significant (GWS) index alleles (or their proxies) from the PGC2 study were overrepresented in Chinese schizophrenia cases, including âŒ50% that achieved nominal significance and âŒ75% that continued to be GWS in the transancestry analysis. The Chinese-only analysis identified seven GWS loci; three of these also were GWS in the transancestry analyses, which identified 109 GWS loci, thus yielding a total of 113 GWS loci (30 novel) in at least one of these analyses. We observed improvements in the fine-mapping resolution at many susceptibility loci. Our results provide several lines of evidence supporting candidate genes at many loci and highlight some pathways for further research. Together, our findings provide novel insight into the genetic architecture and biological etiology of schizophrenia
Addition to âThianthrenation-Enabled Pyrrolidin-2-yl and Tetrahydrofuran-2-yl Methylation of (Hetero)Arenesâ
Addition to
âThianthrenation-Enabled Pyrrolidin-2-yl
and Tetrahydrofuran-2-yl Methylation of (Hetero)Arenes
Microdroplet-Controlled Divergent Reactivity at a Gas-Organic Interface
Gas-liquid Interface plays key roles in many fantastic phenomena due to specific properties. Although remarkable reactivities were benefited from gas-water interface of aqueous microdroplets, it remains unknown for gas-organic interface. This work discovers such extraordinary reactivity of gas-organic interface using organic microdroplets (acetonitrile and other organic solvents). This reactivity at the gas-organic interface facilitated a novel micrordroplet-controlled divergence, i.e., double CâN cleavage in high efficiency (yields > 90% in milliseconds) compared to single CâN bond breakdown and intramolecular cycloarrangement in bulk under harsher conditions from the same imidazolines. This study is not only important to wide applicability and inherent mechanisms of the gas-organic interface but also enables good insights into gas-water and other interface-rich studies in atmospheric and photochemistry, on-water chemistry, biological and biomedical, industrial, and energy
Breaking 10% Efficiency in Semitransparent Solar Cells with Fused-Undecacyclic Electron Acceptor
A fused-undecacyclic
electron acceptor IUIC has been designed,
synthesized and applied in organic solar cells (OSCs) and semitransparent
organic solar cells (ST-OSCs). In comparison with its counterpart,
fused-heptacyclic ITIC4, IUIC with a larger Ï-conjugation and
a stronger electron-donating core exhibits a higher LUMO level (IUIC:
â3. 87 eV vs ITIC4: â3.97 eV), 82 nm red-shifted absorption
with larger extinction coefficient and smaller optical bandgap, and
higher electron mobility. Thus, IUIC-based OSCs show higher values
in open-circuit voltage, short-circuit current density, and thereby
much higher power conversion efficiency (PCE) than those of the ITIC4-based
counterpart. The as-cast OSCs based on PTB7-Th: IUIC without any extra
treatment yield PCEs of up to 11.2%, higher than that of the control
devices based on PTB7-Th: ITIC4 (8.18%). The as-cast ST-OSCs based
on PTB7-Th: IUIC without any extra treatment afford PCEs of up to
10.2% with an average visible transmittance (AVT) of 31%, higher than
those of the control devices based on PTB7-Th: ITIC4 (PCE = 6.42%,
AVT = 28%)
Online Digital Holographic Method for Interface Reaction Monitoring in Lithium-Ion Batteries
Understanding
the reaction mechanisms at the interface of electrode
and electrolyte is both of fundamental interest and essential to improve
lithium-ion battery (LIB) performance. Herein, we report an online digital holographic method to in
situ observe the entire interface change between electrode and electrolyte
in lithium-ions batteries. The accuracy of this technology is well
verified in LiFePO<sub>4</sub>/graphite full-cell systems, graphite/Li
half-cell systems in EC-based and PC-based electrolyte, respectively,
and supported by the characterized results of conventional instruments,
including scanning electron microscopy and X-ray photoelectron spectroscopy.
In particular, the time resolution of the digital holographic method
is 0.04 s and fast enough to distinguish detail reduction process
of ethylene carbonate (EC), for which EC will be first reduced to
generate lithium alkyl carbonates, and then the reduction product
is Li<sub>2</sub>CO<sub>3</sub> to form a stable SEI films. To our
best of knowledge, this is the first report on the reduction order
of the EC solvent and can act as an effective complement to understanding
the formation mechanisms of SEI films
Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer
<div><p>Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) and the underlying molecular mechanisms are not known. In the present study, during induction of radio- or chemo-resistance in NSCLC cells, dynamic analyses revealed that decreased expression of let-7 induced by irradiation or cisplatin resulted in increased expression of its target gene <i>LIN28</i>, and increased expression of LIN28 then contributed to further decreased expression of let-7 by inhibiting its maturation and biogenesis. Moreover, we showed that down-regulation of let-7 and up-regulation of LIN28 expression promoted resistance to irradiation or cisplatin by regulating the single-cell proliferative capability of NSCLC cells. Consequently, in NSCLC cells, let-7 and LIN28 can form a double-negative feedback loop through mutual inhibition, and disturbance of the let-7/LIN28 double-negative feedback loop induced by irradiation or chemotherapeutic drugs can result in radio- and chemo-resistance. In addition, low expression of let-7 and high expression of LIN28 in NSCLC patients was associated significantly with resistance to radiotherapy or chemotherapy. Therefore, our study demonstrated that disturbance of the let-7/LIN28 double-negative feedback loop is involved in the regulation of radio- and chemo-resistance, and that let-7 and LIN28 could be employed as predictive biomarkers of response to radiotherapy or chemotherapy in NSCLC patients.</p></div