2 research outputs found
Structure–Reactivity–Property Relationships in Covalent Adaptable Networks
Polymer networks built out of dynamic covalent bonds
offer the
potential to translate the control and tunability of chemical reactions
to macroscopic physical properties. Under conditions at which these
reactions occur, the topology of covalent adaptable networks (CANs)
can rearrange, meaning that they can flow, self-heal, be remolded,
and respond to stimuli. Materials with these properties are necessary
to fields ranging from sustainability to tissue engineering; thus
the conditions and time scale of network rearrangement must be compatible
with the intended use. The mechanical properties of CANs are based
on the thermodynamics and kinetics of their constituent bonds. Therefore,
strategies are needed that connect the molecular and macroscopic worlds.
In this Perspective, we analyze structure–reactivity–property
relationships for several classes of CANs, illustrating both general
design principles and the predictive potential of linear free energy
relationships (LFERs) applied to CANs. We discuss opportunities in
the field to develop quantitative structure–reactivity–property
relationships and open challenges
Porphyrin–Peptoid Conjugates: Face-to-Face Display of Porphyrins on Peptoid Helices
Distance, orientation, and number controlled porphyrin–peptoid conjugates (PPCs) were efficiently synthesized. Cofacial (<b>1</b>, <b>2</b>, and <b>4</b>), slipped-cofacial (<b>3</b>), and unstructured (<b>5</b>) arrangements of porphyrins provided distinct optical and electronic properties characterized by UV–vis and circular dichroism spectroscopy. In addition, ECCD spectra confirmed the handedness of peptoid helices