Theory of parity violation in compound nuclear states; one particle aspects

In this work we formulate the reaction theory of parity violation in compound nuclear states using Feshbach's projection operator formalism. We derive in this framework a complete set of terms that contribute to the longitudinal asymmetry measured in experiments with polarized epithermal neutrons. We also discuss the parity violating spreading width resulting from this formalism. We then use the above formalism to derive expressions which hold in the case when the doorway state approximation is introduced. In applying the theory we limit ourselves in this work to the case when the parity violating potential and the strong interaction are one-body. In this approximation, using as the doorway the giant spin-dipole resonance and employing well known optical potentials and a time-reversal even, parity odd one-body interaction we calculate or estimate the terms we derived. In our calculations we explicitly orthogonalize the continuum and bound wave functions. We find the effects of orthogonalization to be very important. Our conclusion is that the present one-body theory cannot explain the average longitudinal asymmetry found in the recent polarized neutron experiments. We also confirm the discrepancy, first pointed out by Auerbach and Bowman, that emerges, between the calculated average asymmetry and the parity violating spreading width, when distant doorways are used in the theory.Comment: 37 pages, REVTEX, 5 figures not included (Postscript, available from the authors

Primordial magnetic fields and the HI signal from the epoch of reionization

The implication of primordial magnetic-field-induced structure formation for the HI signal from the epoch of reionization is studied. Using semi-analytic models, we compute both the density and ionization inhomogeneities in this scenario. We show that: (a) The global HI signal can only be seen in emission, unlike in the standard $\Lambda$CDM models, (b) the density perturbations induced by primordial fields, leave distinctive signatures of the magnetic field Jeans' length on the HI two-point correlation function, (c) the length scale of ionization inhomogeneities is \la 1 \rm Mpc. We find that the peak expected signal (two-point correlation function) is $\simeq 10^{-4} \rm K^2$ in the range of scales $0.5\hbox{-}3 \rm Mpc$ for magnetic field strength in the range $5 \times 10^{-10} \hbox{-}3 \times 10^{-9} \rm G$. We also discuss the detectability of the HI signal. The angular resolution of the on-going and planned radio interferometers allows one to probe only the largest magnetic field strengths that we consider. They have the sensitivity to detect the magnetic field-induced features. We show that thefuture SKA has both the angular resolution and the sensitivity to detect the magnetic field-induced signal in the entire range of magnetic field values we consider, in an integration time of one week.Comment: 19 pages, 5 figures, to appear in JCA

Effects of T- and P-odd weak nucleon interaction in nuclei: renormalizations due to residual strong interaction, matrix elements between compound states and their correlations with P-violating matrix elements

Manifestations of P-,T-odd weak interaction between nucleons in nucleus are considered. Renormalization of this interaction due to residual strong interaction is studied. Mean squared matrix elements of P-,T-odd weak interaction between compound states are calculated. Correlators between P-,T-odd and P-odd, T-even weak interaction matrix elements between compound states are considered and estimates for these quantities are obtained.Comment: Submitted to Phys. Rev. C; 21 pages, REVTEX 3, no figure

Induced Parity Nonconserving Interaction and Enhancement of Two-Nucleon Parity Nonconserving Forces

Two-nucleon parity nonconserving (PNC) interaction induced by the single-particle PNC weak potential and the two-nucleon residual strong interaction is considered. An approximate analytical formula for this Induced PNC Interaction (IPNCI) between proton and neutron is derived ($Q({\bf r} {\bf \sigma}_{p} \times {\bf \sigma}_{n}) \delta({\bf r}_{p}-{\bf r}_{n})$), and the interaction constant is estimated. As a result of coherent contributions from the nucleons to the PNC potential, IPNCI is an order of magnitude stronger ($\sim A^{1/3}$) than the residual weak two-nucleon interaction and has a different coordinate and isotopic structure (e.g., the strongest part of IPNCI does not contribute to the PNC mean field). IPNCI plays an important role in the formation of PNC effects, e.g., in neutron-nucleus reactions. In that case, it is a technical way to take into account the contribution of the distant (small) components of a compound state which dominates the result. The absence of such enhancement ($\sim A^{1/3}$) in the case of T- and P-odd interaction completes the picture.Comment: Phys. Rev. C, to appear; 17 pages, revtex 3, no figure

Dragon-kings: mechanisms, statistical methods and empirical evidence

This introductory article presents the special Discussion and Debate volume "From black swans to dragon-kings, is there life beyond power laws?" published in Eur. Phys. J. Special Topics in May 2012. We summarize and put in perspective the contributions into three main themes: (i) mechanisms for dragon-kings, (ii) detection of dragon-kings and statistical tests and (iii) empirical evidence in a large variety of natural and social systems. Overall, we are pleased to witness significant advances both in the introduction and clarification of underlying mechanisms and in the development of novel efficient tests that demonstrate clear evidence for the presence of dragon-kings in many systems. However, this positive view should be balanced by the fact that this remains a very delicate and difficult field, if only due to the scarcity of data as well as the extraordinary important implications with respect to hazard assessment, risk control and predictability.Comment: 20 page

A tumor focused approach to resolving the etiology of DNA mismatch repair deficient tumors classified as suspected Lynch syndrome

Published online 26 April 2023Routine screening of tumors for DNA mismatch repair (MMR) deficiency (dMMR) in colorectal (CRC), endometrial (EC) and sebaceous skin (SST) tumors leads to a significant proportion of unresolved cases classified as suspected Lynch syndrome (SLS). SLS cases (n = 135) were recruited from Family Cancer Clinics across Australia and New Zealand. Targeted panel sequencing was performed on tumor (n = 137; 80×CRCs, 33×ECs and 24xSSTs) and matched blood-derived DNA to assess for microsatellite instability status, tumor mutation burden, COSMIC tumor mutational signatures and to identify germline and somatic MMR gene variants. MMR immunohistochemistry (IHC) and MLH1 promoter methylation were repeated. In total, 86.9% of the 137 SLS tumors could be resolved into established subtypes. For 22.6% of these resolved SLS cases, primary MLH1 epimutations (2.2%) as well as previously undetected germline MMR pathogenic variants (1.5%), tumor MLH1 methylation (13.1%) or false positive dMMR IHC (5.8%) results were identified. Double somatic MMR gene mutations were the major cause of dMMR identified across each tumor type (73.9% of resolved cases, 64.2% overall, 70% of CRC, 45.5% of ECs and 70.8% of SSTs). The unresolved SLS tumors (13.1%) comprised tumors with only a single somatic (7.3%) or no somatic (5.8%) MMR gene mutations. A tumor-focused testing approach reclassified 86.9% of SLS into Lynch syndrome, sporadic dMMR or MMR-proficient cases. These findings support the incorporation of tumor sequencing and alternate MLH1 methylation assays into clinical diagnostics to reduce the number of SLS patients and provide more appropriate surveillance and screening recommendations.Romy Walker ... Nicola Poplawski ... et al. and for the Family Cancer Clinics of Australi

Demographic characteristics of horses donated to the North Carolina State University Equine Health Center, 1996–2008

<b>Objective—</b>To determine demographic characteristics of horses donated to the North Carolina State University Equine Health Center (EHC) between 1996 and 2008. <br></br> <b>Design—</b>Retrospective cohort study. <br></br> <b>Animals—</b>122 horses donated to the EHC between January 1996 and December 2008, and 246 horses offered for donation to the EHC between January 2007 and December 2008. <br></br> <b>Procedures—</b>Telephone and medical records were examined. Data were collected in 5 categories: age, sex, breed, reason for donation, and use prior to donation. <br></br> <b>Results—</b>From January 1996 through December 2008, 122 horses were donated to the EHC (median, 3 horses/y; range, 0 to 39 horses/y). There were 131 and 115 horses offered for donation during 2007 and 2008, respectively, of which 38 and 23 were accepted. Mean ± SD age of horses offered for donation during 2007 and 2008 was 12.7 ± 6.7 years, with 75 of the 246 (30.5%) horses between 6 and 10 years old. Musculoskeletal disease was the most commonly listed reason horses were offered for donation (115/240 [47.9%]). <br></br> <b>Conclusions and Clinical Relevance—</b>Results indicated that unwanted horses donated to the EHC between 1996 and 2008 spanned a wide range of ages and breeds and included both males and females. The most common reason given for unwanted horses offered for donation during 2007 and 2008 was musculoskeletal disease, with degenerative joint disease, lameness of undetermined cause, laminitis, and navicular disease being the most common musculoskeletal conditions