200 research outputs found
Scanless functional imaging of hippocampal networks using patterned two-photon illumination through grin lenses
From progenitors to integrated neurons: Role of neurotransmitters in adult olfactory neurogenesis.
GABAergic phenotypic differentiation of a subpopulation of subventricular derived migrating progenitors
Adult Born Olfactory Bulb Dopaminergic Interneurons: Molecular Determinants and Experience-Dependent Plasticity
The olfactory bulb (OB) is a highly plastic brain region involved in the early processing of olfactory information. A remarkably feature of the OB circuits in rodents is the constitutive integration of new neurons that takes place during adulthood. Newborn cells in the adult OB are mostly inhibitory interneurons belonging to chemically, morphologically and functionally heterogeneous types. Although there is general agreement that adult neurogenesis in the OB plays a key role in sensory information processing and olfaction-related plasticity, the contribution of each interneuron subtype to such functions is far to be elucidated. Here, we focus on the dopaminergic (DA) interneurons: we highlight recent findings about their morphological features and then describe the molecular factors required for the specification/differentiation and maintenance of the DA phenotype in adult born neurons. We also discuss dynamic changes of the DA interneuron population related to age, environmental stimuli and lesions, and their possible functional implications
Differential expression of neuregulins and their receptors in the olfactory bulb layers of the developing mouse.
Parvalbumin-positive inhibitory interneurons oppose propagation but favor generation of focal epileptiform activity
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