Contagious Period for Pandemic (H1N1) 2009

Most infected persons shed live virus after fever abated

Association between the 2008–09 Seasonal Influenza Vaccine and Pandemic H1N1 Illness during Spring–Summer 2009: Four Observational Studies from Canada

In three case-control studies and a household transmission cohort, Danuta Skowronski and colleagues find an association between prior seasonal flu vaccination and increased risk of 2009 pandemic H1N1 flu

Étude de la mortalité infantile en Grande Comore

Montréal Trigonix inc. 201

Éthique du consentement à l’ère des réseaux d’information en matière de santé

Un consentement de portée générale qui permettrait aux professionnels de la santé d’accéder à l’ensemble des dossiers cliniques en réseau est insuffisant pour mettre en confiance le patient. Dans un contexte de dossiers cliniques interconnectés, le consentement du patient doit être vu comme un mécanisme flexible pouvant être modulé selon la sensibilité des renseignements et les circonstances d’utilisation.This article shows that a general consent allowing professionals to access all clinical records is not sufficient to bring confidence among patients. In the context of interconnected clinical records, patient’s consent must be seen as a flexible mechanism that could vary according to the sensivity of the information and clinical circumstances

Absence of association between Guillain-Barré syndrome hospitalizations and HPV-vaccine

Background: In 2008, a school-based human papilloma virus (HPV) vaccination program was implemented in the province of Québec. Grade 4 girls (9–10 years old) are routinely vaccinated and grade 9 to 12 girls (14–17 years old) were eligible for the catch-up vaccination. Vaccine coverage of the targeted cohorts was estimated at 76–81%. To assess if HPV vaccination is associated with an increase in GBS hospitalisation, we compared the hospitalization rates of GBS in HPV vaccination targeted and non-targeted groups. Methods: Hospital discharge records with a GBS code as the main diagnosis during the 1999–2014 period were retrieved. Incidence rates according to program eligibility were computed and adjusted relative risk in the targeted groups was estimated by Poisson regression. Results: The overall incidence rate in the 7 to 17 year-olds was 0.73/100,000 p-y. There was no increase in GBS incidence in HPV vaccination targeted groups (adjusted IRR = 0.81, 95%CI: 0.29–2.26). Conclusion: No signal of increase GBS hospitalisation incidence in the HPV-vaccine targeted group was detected in the hospitalisation database

Santé publique : le contrôle des maladies méningococciques au Québec

Les décisions de santé publique doivent être fondées sur les données scientifiques résultant d’une recherche systématique de qualité et l’expertise des cliniciens et des professionnels de la santé communautaire. L’histoire du contrôle des maladies méningococciques de sérogroupe C au Québec durant la dernière décennie illustre cette théorie, et souligne l’importance d’intégrer dans tout programme de santé publique une composante évaluative et, si possible, un volet de recherche et de développement technologique.A first outbreak of serogroup C meningococcal disease occurred in the province of Quebec in 1990-1992 and lead to a mass immunization campaign using polysaccharide vaccines. In 2001, a second outbreak was identified and a mass vaccination campaign was carried out, using the newly licensed conjugate vaccine. Clinical, epidemiological, economic and social studies were instrumental in the decision making for implementing these control programs

Impact of vaccine delays at the 2, 4, 6 and 12 month visits on incomplete vaccination status by 24 months of age in Quebec, Canada

Abstract Background Timeliness in the administration of recommended vaccines is often evaluated using vaccine delays and provides more information regarding the susceptibility of children to vaccine-preventable diseases compared with vaccine coverage at a given age. The importance of on-time administration of vaccines scheduled at the first visit is well documented, but data are scarce about the impact of vaccine delays at other visits on vaccination status by 24 months of age. Using vaccine delays for the first three doses of DTaP-containing vaccines and for the first dose of measles-containing vaccines as markers of timeliness at the 2, 4, 6 and 12 month visits, we estimated the proportion of incomplete vaccination status by 24 months of age attributable to a vaccine delay at each of these visits. Methods We used the data from six cross-sectional coverage surveys conducted in the Province of Quebec from 2006 to 2016 which included 7183 children randomly selected from the universal health insurance database. A vaccine dose was considered delayed if received 30 days or more after the recommended age. The impact of new vaccine delays at each visit on incomplete vaccination status by 24 months of age was estimated with the attributable risk in the population. Results The proportion of children with vaccine delay was 5.4% at 2 months, 13.3% at 4 months, 23.1% at 6 months and 23.6% at 12 months. Overall, 72.5% of all 2-year-old children with an incomplete status by 24 months were attributable with a vaccine delay, of which 16.1% were attributable with a first vaccine delay at 2 months, 10.6% at 4 months, 14.0% at 6 months and 31.8% at 12 months. Conclusions While great emphasis has been put on vaccine delays at the first vaccination visit, the prevalence of vaccine delays was greater with later visits and most children with an incomplete vaccination status by 24 months had a vaccine delay occurring during these later visits. Interventions to improve timeliness should address vaccine delays at each visit and not only focus on the first visit

Hospitalizations for Diarrhea in Quebec Children from 1985 to 1998: Estimates of Rotavirus-Associated Diarrhea

OBJECTIVE: To characterize the incidence and duration of hospitalization due to diarrhea and to assess the proportion of hospitalizations that are attributed to rotavirus-associated diarrhea