Percentages of Tregs (FoxP3⁺CD25^High CD4⁺ T cells) in carriers and non carriers of the CCR5Δ32 polymorphism.

<p>Horizontal lines represent the median percentage.</p

Percentages of IL-4, IL-17 and IFN-γ secreting CD4 and CD8+ T cells in carriers and non carriers of the CCR5Δ32 polymorphism.

<p>In the left panel the frequencies of IL-4, IL-17 and IFN-γ secreting cells among CD69+, CD4+ T cells from non carriers (n = 9) and carriers (n = 10) of the CCR5Δ32 genotype are shown. In the right panel the frequencies of IL-4, IL-17 and IFN-γ secreting cells among CD69+, CD8+ T cells from non carriers (n = 9) and carriers (n = 10) of the CCR5Δ32 polymorphism are shown. Horizontal lines represent the median percentage.</p

Flow cytometric characterization of CD4 and CD8 T cell subsets from CCR5 wild type (left panel) and CCR5 deletion 32 (right panel).

<p>PBMCs were stimulated <i>in vitro</i> with PMA and Ca-ionophore for 4 hours in the presence of BFA. The CD4 and CD8 T cell subsets were then assessed for the expression of activation marker CD69 versus intracellular cytokine (IFN-γ, IL-17, and IL-4). The percentage in the upper right corner of each plot represents the net percentage of positive cells.</p

IFN-γ and IL-4 ELISA per 2,5×10⁶ PBMCs in carriers and non carriers of the CCR5Δ32 genotype.

<p>Levels of IFN-γ and IL-4 after stimulation from carriers (n = 10) and non carriers (n = 9) are shown. Horizontal lines represent the medians.</p

Baseline characteristics.

<p>Data are presented as number (percentage), mean (SD).</p

Characteristics of Hispanic classical Hodgkin lymphoma patients.

<p>Characteristics of Hispanic classical Hodgkin lymphoma patients.</p

The association between HLA-A*01 or HLA-A*02 and EBV tumor status in Hispanic classical Hodgkin lymphoma patients.

<p>The association between HLA-A*01 or HLA-A*02 and EBV tumor status in Hispanic classical Hodgkin lymphoma patients.</p

Primers used for the HLA-A*01 and HLA-*02 quantitative PCR.

<p>Primers used for the HLA-A*01 and HLA-*02 quantitative PCR.</p

Association between HLA class I or II expression in Hodgkin Reed Sternberg cells and presence of Epstein-Barr Virus (EBV), Nodular Sclerosis (NS) histology, birthplace, sex and HLA type in Hispanic classical Hodgkin lymphoma patients.

<p>Association between HLA class I or II expression in Hodgkin Reed Sternberg cells and presence of Epstein-Barr Virus (EBV), Nodular Sclerosis (NS) histology, birthplace, sex and HLA type in Hispanic classical Hodgkin lymphoma patients.</p

The association between EBV tumor status and HLA class I or HLA class II expression in Hispanic classical Hodgkin lymphoma patients.

<p>The association between EBV tumor status and HLA class I or HLA class II expression in Hispanic classical Hodgkin lymphoma patients.</p