769 research outputs found
To Blur the Boundaries of Fiction and Translation
The Fictions of Translation sammelt Aufsätze aus der dritten Transfiction Tagung, die in Montreal im Mai 2015 stattgefunden hat. Wie auch die vorigen Bände dieser Tagungsserie versucht dieser Sammelband, den Begriff ‘transfiction’ als Grundlage einer neuen Teildisziplin der Translation Studies zu etablieren. Die 16 Beiträge untersuchen ein breites Spektrum von ‘translation fictions,’ von Pseudoübersetzungen, (Nicht-)Übersetzer- und (Selbst-)Übersetzer-Biografien bis hin zu Diskursen innerhalb von Übersetzungsinstitutionen. Dadurch zeigen sie eindrucksvoll das Potenzial von Übersetzungen und ‘translation fictions,’ um zu neuen Erkenntnissen über vergangene sowie zeitgenössische soziale und politische Lagen zu gelangen.The Fictions of Translation gathers papers from the third Transfiction conference, which took place in Montreal in May 2015. As with the previous publications of the conference series, this volume aims to establish the concept of ‘transfiction’ as the basis of a new subdiscipline in translation studies. The 16 chapters of this collection explore a wide spectrum of ‘translation fictions’ that range from pseudo-translations, (non-)translator and (self-)translator biographies, to the discourse of translation institutions to show the potential of translation and ‘translation fictions’ in providing insights into past or contemporary social and political situations.
 
Alien Registration- Boucher, Marie A. (Augusta, Kennebec County)
https://digitalmaine.com/alien_docs/18378/thumbnail.jp
Alien Registration- Boucher, Marie (Caribou, Aroostook County)
https://digitalmaine.com/alien_docs/25989/thumbnail.jp
Moving beyond the cost–loss ratio : economic assessment of streamflow forecasts for a risk-averse decision maker
A large effort has been made over the past 10
years to promote the operational use of probabilistic or ensemble
streamflow forecasts. Numerous studies have shown
that ensemble forecasts are of higher quality than deterministic
ones. Many studies also conclude that decisions based
on ensemble rather than deterministic forecasts lead to better
decisions in the context of flood mitigation. Hence, it is
believed that ensemble forecasts possess a greater economic
and social value for both decision makers and the general
population. However, the vast majority of, if not all, existing
hydro-economic studies rely on a cost–loss ratio framework
that assumes a risk-neutral decision maker. To overcome
this important flaw, this study borrows from economics
and evaluates the economic value of early warning flood systems
using the well-known Constant Absolute Risk Aversion
(CARA) utility function, which explicitly accounts for the
level of risk aversion of the decision maker. This new framework
allows for the full exploitation of the information related
to a forecasts’ uncertainty, making it especially suited
for the economic assessment of ensemble or probabilistic
forecasts. Rather than comparing deterministic and ensemble
forecasts, this study focuses on comparing different types of
ensemble forecasts. There are multiple ways of assessing and
representing forecast uncertainty. Consequently, there exist
many different means of building an ensemble forecasting
system for future streamflow. One such possibility is to dress
deterministic forecasts using the statistics of past error forecasts.
Such dressing methods are popular among operational agencies because of their simplicity and intuitiveness. Another
approach is the use of ensemble meteorological forecasts
for precipitation and temperature, which are then provided
as inputs to one or many hydrological model(s). In
this study, three concurrent ensemble streamflow forecasting
systems are compared: simple statistically dressed deterministic
forecasts, forecasts based on meteorological ensembles,
and a variant of the latter that also includes an estimation
of state variable uncertainty. This comparison takes
place for the Montmorency River, a small flood-prone watershed
in southern central Quebec, Canada. The assessment
of forecasts is performed for lead times of 1 to 5 days, both
in terms of forecasts’ quality (relative to the corresponding
record of observations) and in terms of economic value, using
the new proposed framework based on the CARA utility
function. It is found that the economic value of a forecast
for a risk-averse decision maker is closely linked to the forecast
reliability in predicting the upper tail of the streamflow
distribution. Hence, post-processing forecasts to avoid overforecasting
could help improve both the quality and the value
of forecasts
Accounting for three sources of uncertainty in ensemble hydrological forecasting
Seeking more accuracy and reliability, the hydrometeorological
community has developed several tools
to decipher the different sources of uncertainty in relevant
modeling processes. Among them, the ensemble Kalman filter
(EnKF), multimodel approaches and meteorological ensemble
forecasting proved to have the capability to improve
upon deterministic hydrological forecast. This study aims to
untangle the sources of uncertainty by studying the combination
of these tools and assessing their respective contribution
to the overall forecast quality. Each of these components is
able to capture a certain aspect of the total uncertainty and
improve the forecast at different stages in the forecasting
process by using different means. Their combination outperforms
any of the tools used solely. The EnKF is shown to
contribute largely to the ensemble accuracy and dispersion,
indicating that the initial conditions uncertainty is dominant.
However, it fails to maintain the required dispersion throughout
the entire forecast horizon and needs to be supported by
a multimodel approach to take into account structural uncertainty.
Moreover, the multimodel approach contributes to
improving the general forecasting performance and prevents
this performance from falling into the model selection pitfall
since models differ strongly in their ability. Finally, the use of
probabilistic meteorological forcing was found to contribute
mostly to long lead time reliability. Particular attention needs
to be paid to the combination of the tools, especially in the
EnKF tuning to avoid overlapping in error decipherin
The effects of PCB126 on intra-hepatic mechanisms associated with non alcoholic fatty liver disease
Role of zoledronic acid in the prevention and treatment of osteoporosis
Taken once a year, intravenous zoledronic acid (Zol) (Reclast® or Aclasta®) is a third-generation nitrogen-containing bisphosphonate that is effective compared with placebo in reducing the risk of fractures in patients with postmenopausal osteoporosis and recent low-trauma hip fracture. In glucocorticoid-induced osteoporosis, there is no significant difference between Zol and risedronate for new fractures. Improvements in bone mineral density and early reduction of bone remodeling markers are observed in postmenopausal osteoporosis, recent low-trauma hip fracture, and glucocorticoid-induced osteoporosis. Given that Zol is generally well tolerated and very convenient, it is an interesting therapeutic option for aging patients who take multiple oral drugs, who have adherence or gastrointestinal tolerance issues, and who have an indication for oral bisphosphonates. Zol is not recommended for patients with severe renal impairment. Vitamin D deficiency should be corrected before the administration of Zol
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