Gender, class and space in the field of parenthood comparing middle-class fractions in Amsterdam and London

This paper argues that becoming a parent/carer can be seen as a new field of social relations and suggests how gender is the key mechanism in the reconfiguration of class relations in this field. By conceptualising parenthood as a field, that is a social world with specific stakes and rules, this study suggests that residential decisions and strategies developed by different middle-class households do not solely depend on their class habitus, but also on gendered positions and dispositions in respect to division of labour, child care and school choice. Drawing on interview data from London and Amsterdam, this study re-addresses the issue of middle–class time-space trajectories at a specific period in the life course. We contend that the middle classes are not just differentiated by various orientations of capital (economic versus cultural) but that interaction of class and gender is also key for understanding practices of the middle classes as they enter the field of parenthood. These practices are strongly influenced by labour market and welfare regimes (as the Netherlands/England comparison makes clear). In the new field of parenthood the work of realigning class habitus (through social reproduction) is highly gendered, but to different degrees that are made evident in the different neighbourhood settings. In terms of urban space this points to the significance of the particular neighbourhood structure and opportunities of the city as a whole as well as a more active idea of the role of space in the particular working out of class and gender in specific neighbourhood contexts. Urban space is a situating framework and an active process in trajectories of social reproduction

Accounting for material scatter in sheet metal forming simulations

Robust design of forming processes is gaining attention throughout the industry. To analyze the robustness of a sheet metal forming process using Finite Element (FE) simulations, an accurate input in terms of parameter variation is required. This paper presents a pragmatic, accurate and economic approach for measuring and modeling one of the main inputs, i.e. material properties and its associated scattering. For the purpose of this research, samples of 41 coils of a forming steel DX54D+Z (EN 10327:2004) from multiple batches have been collected. Fully determining the stochastic material behavior to the required accuracy for precise modeling in FE simulations would involve performing many mechanical experiments. Instead, the present work combines mechanical testing and texture analysis to limit the required effort. Moreover, use is made of the correlations between the material parameters to efficiently model the material property scatter for use in the numerical robustness analysis. The proposed approach is validated by the forming of a series of cup products using the collected material. The observed experimental scatter can be reproduced efficiently using FE simulations, demonstrating the potential of the modeling approach and robustness analysis in general

The transition to parenthood in urban space: continuity and disruption of embodied experience and spatial practice.

This paper explores the impacts of the transition to parenthood on the relationship between (from a Bourdieusian perspective) habitus and field in social reproduction. The paper is based on a longitudinal study of white middle-class gentrifier households in Amsterdam before and after childbirth. The study reveals the disruptive (as well as re-configurative) impact of parenthood as transition, even for this relatively privileged group (in terms of legitimated habitus and spatial discretion and mobility). Our findings strongly suggest the highly gendered nature of this transition, and also reveal the significance of spatial dimensions of this gendered experience – from embodiment all the way through to changing relationships in urban space. These impacts suggest parenthood as a distinct ‘field’ of social struggle and emphasise the significance of gender and spatial experience in understanding habitus-field relations, alongside the more acknowledged temporalities of social reproduction

Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease

Cigarette smoke-induced release of pro-inflammatory cytokines including interleukin-8 (IL-8) from inflammatory as well as structural cells in the airways, including airway smooth muscle (ASM) cells, may contribute to the development of chronic obstructive pulmonary disease (COPD). Despite the wide use of pharmacological treatment aimed at increasing intracellular levels of the endogenous suppressor cyclic AMP (cAMP), little is known about its exact mechanism of action. We report here that next to the β2-agonist fenoterol, direct and specific activation of either exchange protein directly activated by cAMP (Epac) or protein kinase A (PKA) reduced cigarette smoke extract (CSE)-induced IL-8 mRNA expression and protein release by human ASM cells. CSE-induced IκBα-degradation and p65 nuclear translocation, processes that were primarily reversed by Epac activation. Further, CSE increased extracellular signal-regulated kinase (ERK) phosphorylation, which was selectively reduced by PKA activation. CSE decreased Epac1 expression, but did not affect Epac2 and PKA expression. Importantly, Epac1 expression was also reduced in lung tissue from COPD patients. In conclusion, Epac and PKA decrease CSE-induced IL-8 release by human ASM cells via inhibition of NF-κB and ERK, respectively, pointing at these cAMP effectors as potential targets for anti-inflammatory therapy in COPD. However, cigarette smoke exposure may reduce anti-inflammatory effects of cAMP elevating agents via down-regulation of Epac1

When the spell is broken: gentrification, urban tourism and privileged discontent in the Amsterdam canal district

Expansion of urban tourism in historic districts in European cities is putting increasing pressure on these areas as places to live. In Amsterdam, an ever-growing number of tourists visit the famous canal district, which also forms the home of a group of long-term, upper-middle-class residents. While such residents are generally depicted as instigators of urban transformation, in this case, they are on the receiving end. Bringing together the literature on the socio-spatial impact of tourism, belonging and the lived experience of place, this article explores the changing relationship between these established residents and their neighbourhood and provides insight into their growing sense of discontent and even powerlessness in the face of neighbourhood change