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Quantile–quantile plots for the four genome-wide analyses.
<p>(A) Analysis of the whole sample (<i>n</i> = 1,790); (B) analysis of SRI-treated individuals (<i>n</i> = 1,222); (C) analysis of NRI-treated individuals (<i>n</i> = 568); (D) gene-by-drug interaction analysis in the randomly allocated individuals (<i>n</i> = 949). The shaded area is the 95% confidence interval of values expected under a uniform distribution.</p