Effect of tissue glue versus suture in pterygium surgery in a tertiary care center of North-East India

Background: Pterygium is a triangular fibrovascular tissue of conjunctiva encroaching on to the cornea. Currently, conjunctival autograft technique after excision is reported as the most suitable and safest method. The autograft transplantation can be done either with the help of suture or tissue adhesives. Objective of the study was to evaluate the effects of tissue glue versus suture in limbal conjunctival autograft transplantation among the patients undergoing pterygium excision.Methods: A prospective study was carried out in a tertiary eye care hospital. 60 patients with primary pterygium underwent limbal conjunctival autograft transplantation. They were enrolled into two groups, group-A (tissue glue, N=30) and group-B (suture group, N=30). Operative time, postoperative patient comfort and recurrence of pterygium were assessed. The patients were followed-up for 6 months.Results: The mean surgical time in fibrin glue group (23.56±2.80) was significantly less compared to suture (30.78±2.20) group with p0.005).Conclusions: The use of fibrin glue for securing the limbal conjunctival autograft in pterygium surgery significantly reduces the operating time and postoperative discomfort

Reaction of amines with ortho chloro carbonyl compounds and its derivatives: A novel one pot synthesis of pyrozolo, benzodiazepino, cyclodecano and cyclotridecano derivatives of naphthalene at room temperature.

2112-2114Reaction of 1-chloro-6-methoxy-3,4-dihydro naphthalene-2-carbaldehyde 1 with hydrazine hydrate 7a, phenylhydrazine 7b, 2,4-dinitro phenylhydrazine 7c, ethylene diamine 8, ortho phenylene diamine 9, ethylene triamine 10 and ethylene tetrarnine 11 produce pyrozolo 12(a-c), benzodiazepino 13-14,cyclodecano 15 and cyclotridecano 16 derivatives of naphthalene. The behaviour of the above diamines 7(a-c) and 9 compounds with malononitrile and nitrone derivatives, which were derived from 1, are also discussed