27 research outputs found
Psychotic and depressive symptoms after gabapentin treatment
Gabapentin, one of the antiepileptics, shows its effects via voltage-gated calcium
channels. Sedation and mood elevation are among its side effects. The positive effects
of antiepileptics such as valproate and carbamazepine as mood stabilizers have raised
the hope that other antiepileptics may as well be efficacious in the treatment of mood
disorders. However, relevant research data have not proven success of newer antiepileptics.
This article presents the negative side effects of gabapentin such as psychotic
and depressive symptoms, which occur shortly after its use. The use of
gabapentin in mood disorders is discussed through these side effects