66 research outputs found

    Ordung: la Scuola di Friburgo e l’etica economica di Wilhelm Röpke

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    In this essay, we will focus on ordoliberal thought and the contribution of Wilhelm Röpke, with reference to the positions he expressed in the Italian press and the relationship between economics, ethics and the Magisterium of the Church. In this framework, among the different sensitivities of the Ordo liberals, Röpke’s emphasis on the freedom and dignity of every man seems to place his work within the tradition of Catholic social thought, anticipating, in some ways, his later developments on the themes of the market, competition and solidarity, in relation to the Social Market Economy.In this essay, we will focus on ordoliberal thought and the contribution of Wilhelm Röpke, with reference to the positions he expressed in the Italian press and the relationship between economics, ethics and the Magisterium of the Church. In this framework, among the different sensitivities of the Ordo liberals, Röpke’s emphasis on the freedom and dignity of every man seems to place his work within the tradition of Catholic social thought, anticipating, in some ways, his later developments on the themes of the market, competition and solidarity, in relation to the Social Market Economy

    Management and Oncologic Outcomes of Close and Positive Margins after Transoral CO2 Laser Microsurgery for Early Glottic Carcinoma

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    Background: The present study analyzed the impact of margin status on local control and survival, and the management of close/positive margins after transoral CO2 laser microsurgery for early glottic carcinoma. Methods: 351 patients (328 males, 23 females, mean age 65.6 years) underwent surgery. We identified the following margin statuses: negative, close superficial (CS), close deep (CD), positive single superficial (SS), positive multiple superficial (MS), and positive deep (DEEP). Results: A total of 286 patients (81.5%) had negative margins, 23 (6.5%) had close margins (8 CS, 15 CD) and 42 (12%) had positive margins (16 SS, 9 MS, 17 DEEP). Among the 65 patients with close/positive margins, 44 patients underwent enlargement, 6 radiotherapy and 15 follow-up. Twenty-two patients (6.3%) recurred. Patients with DEEP or CD margins showed a higher risk of recurrence (hazard ratios of 2.863 and 2.537, respectively), compared to patients with negative margins. Local control with laser alone, overall laryngeal preservation and disease-specific survival decreased significantly in patients with DEEP margins (57.5%, 86.9% and 92.9%, p < 0.05). Conclusions: Patients with CS or SS margins could be safely submitted to follow-up. In the case of CD and MS margins, any additional treatment should be discussed with the patient. In the case of DEEP margin, additional treatment is always recommended

    Survival in Patients with Primary Parotid Gland Carcinoma after Surgery—Results of a Single-Centre Study

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    This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four patients with a primary parotid malignancy were included in the study, with one bilateral case in this cohort. Patients were classified as stage I–II in 39 cases and stage III–IV in 26 cases. The five-year overall survival (OS), disease-specific survival (DSS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) rates were 78.4%, 89%, 92.5%, and 87.1%, respectively. Univariate analysis showed that high-risk histology, stage IV disease, lymphovascular invasion, perineural invasion, node metastasis, skin involvement, facial nerve involvement, and positive or close margins were risk factors associated with poorer outcomes. At present, the best evidence suggests that radical surgery should be the standard approach, and adjuvant therapy, in terms of radiotherapy/chemoradiotherapy, is recommended in patients with risk factors

    A bound on the cross-validation estimate for algorithm assessment

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    TR/IRIDIA/1999-010info:eu-repo/semantics/publishe

    The Lazy Learning Toolbox. For Use with Matlab

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    TR/IRIDIA/1999-007info:eu-repo/semantics/publishe

    A bound on the cross-validation estimate for algorithm assessment

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    info:eu-repo/semantics/publishe

    Toolbox for neuro-fuzzy Identification and data analysis, for use with matlab

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    Technical Report TR/IRIDIA/99-9info:eu-repo/semantics/publishe
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