2,299 research outputs found

    Interacting Strings in Matrix String Theory

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    It is here explained how the Green-Schwarz superstring theory arises from Matrix String Theory. This is obtained as the strong YM-coupling limit of the theory expanded around its BPS instantonic configurations, via the identification of the interacting string diagram with the spectral curve of the relevant configuration. Both the GS action and the perturbative weight gs−χg_s^{-\chi}, where χ\chi is the Euler characteristic of the world-sheet surface and gsg_s the string coupling, are obtained.Comment: 11 pages, no figures, two references adde

    Extracellular vesicles in cardiac repair and regeneration: Beyond stem-cell-based approaches.

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    The adult human heart poorly regenerate after injury due to the low self-renewal capability retained by adult cardiomyocytes. In the last two decades, several clinical studies have reported the ability of stem cells to induce cardiac regeneration. However, low cell integration and survival into the tissue has limited stem-cell-based clinical approaches. More recently, the release of paracrine mediators including extracellular vesicles (EV) has been recognized as the most relevant mechanism driving benefits upon cell-based therapy. In particular, EV have emerged as key mediators of cardiac repair after damage, in terms of reduction of apoptosis, resolution of inflammation and new blood vessel formation. Herein, mechanisms involved in cardiac damage and regeneration, and current applications of EV and their small non-coding RNAs (miRNAs) in regenerative medicine are discussed

    Mesoporous Titania: Synthesis, Properties and Comparison with Non-Porous Titania

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    Some relevant physico-chemical and photocatalytic properties of ordered mesoporous TiO2 as obtained by template-assisted synthesis methods are reported. After a review of the crucial aspects related to different synthesis procedures reported by the literature, the focus is pointed on the (often) superior physico-chemical properties of ordered mesoporous TiO2 with respect to (commercial) bulk TiO2. Those are essentially higher specific surface area and ordered mesoporosity; possibility to control the formation of different crystalline phases by varying the synthesis conditions and possibility to obtain films, nanoparticles with different morphologies and/or materials with hierarchical porosity. Although mesoporous TiO2 is extensively studied for many applications in the fields of photocatalysis, energy and biomedicine, this chapter focuses on the use of mesoporous TiO2 in environmental photocatalysis, by putting in evidence how the physico-chemical properties of the material may affect its photocatalytic behaviour and how mesoporous TiO2 behaves in comparison with commercial TiO2 samples

    Photocatalysts for organics degradation

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    Organics degradation is one of the challenges of Advanced Oxidation Processes (AOPs), which are mainly employed for the removal of water and air pollutants [...

    Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection

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    Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe resections may result in material specific memory impairment, typically verbal memory decline following left and visual memory decline after right anterior temporal lobe resection. This study aimed to investigate reorganization of memory functions in temporal lobe epilepsy and to determine whether preoperative memory functional magnetic resonance imaging may predict memory changes following anterior temporal lobe resection. We studied 72 patients with unilateral medial temporal lobe epilepsy (41 left) and 20 healthy controls. A functional magnetic resonance imaging memory encoding paradigm for pictures, words and faces was used testing verbal and visual memory in a single scanning session on a 3T magnetic resonance imaging scanner. Fifty-four patients subsequently underwent left (29) or right (25) anterior temporal lobe resection. Verbal and design learning were assessed before and 4 months after surgery. Event-related functional magnetic resonance imaging analysis revealed that in left temporal lobe epilepsy, greater left hippocampal activation for word encoding correlated with better verbal memory. In right temporal lobe epilepsy, greater right hippocampal activation for face encoding correlated with better visual memory. In left temporal lobe epilepsy, greater left than right anterior hippocampal activation on word encoding correlated with greater verbal memory decline after left anterior temporal lobe resection, while greater left than right posterior hippocampal activation correlated with better postoperative verbal memory outcome. In right temporal lobe epilepsy, greater right than left anterior hippocampal functional magnetic resonance imaging activation on face encoding predicted greater visual memory decline after right anterior temporal lobe resection, while greater right than left posterior hippocampal activation correlated with better visual memory outcome. Stepwise linear regression identified asymmetry of activation for encoding words and faces in the ipsilateral anterior medial temporal lobe as strongest predictors for postoperative verbal and visual memory decline. Activation asymmetry, language lateralization and performance on preoperative neuropsychological tests predicted clinically significant verbal memory decline in all patients who underwent left anterior temporal lobe resection, but were less able to predict visual memory decline after right anterior temporal lobe resection. Preoperative memory functional magnetic resonance imaging was the strongest predictor of verbal and visual memory decline following anterior temporal lobe resection. Preoperatively, verbal and visual memory function utilized the damaged, ipsilateral hippocampus and also the contralateral hippocampus. Memory function in the ipsilateral posterior hippocampus may contribute to better preservation of memory after surgery

    Algebraic-geometrical formulation of two-dimensional quantum gravity

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    We find a volume form on moduli space of double punctured Riemann surfaces whose integral satisfies the Painlev\'e I recursion relations of the genus expansion of the specific heat of 2D gravity. This allows us to express the asymptotic expansion of the specific heat as an integral on an infinite dimensional moduli space in the spirit of Friedan-Shenker approach. We outline a conjectural derivation of such recursion relations using the Duistermaat-Heckman theorem.Comment: 10 pages, Latex fil

    Buoyancy and local friction effects on rockfill settlements: A discrete modelling

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    AbstractMeasured displacements in the upstream shell of rockfill dams show some settlements which can reach a few meters with water levels changes, especially during the first impounding, whereas downstream displacements are smaller. Complementary phenomena are responsible for rockfill collapse due to wetting. Here we numerically investigate the effects of buoyancy forces and the decrease in the coefficient of friction with water on a rockfill column maintained by vertical rigid walls and progressively filled with water. Numerical simulations of the settlements of the rockfill column, using the Contact Dynamics method, are presented. Buoyancy forces seem to have only a negligible influence on the granular pile. Decrease in the friction angle of the rock with water induces rearrangements of the medium, all the more as the decrease is significant. These dynamic rearrangements exhibit an irregular temporal evolution of the granular medium which can be characterized by a phenomenon of local “crisis”. Analysis of the settlements shows that these two combined effects are not the major cause of the settlements observed in rockfill dams and that they cannot in particular explain the settlements
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