Activity In Vitro of Clotrimazole against Canine Methicillin-Resistant and Susceptible Staphylococcus pseudintermedius

Emergence of multidrug-resistance in Staphylococcus pseudintermedius (SP) has increased interest in topical therapy as an alternative to systemic antibiotics in canine pyoderma. The antifungal imidazole, clotrimazole, is contained in numerous licensed canine ear preparations. Its in vitro activity against SP has not been evaluated, although previous studies have shown that the related imidazole, miconazole, has significant anti-staphylococcal efficacy. We therefore determined minimum inhibitory concentrations (MICs) of clotrimazole amongst 50 SP isolates (25 methicillin-resistant [MR]SP and susceptible [MS]SP) collected from dogs in Germany during 2010–2011 using an agar dilution method (CLSI VET01-A4). MICs amongst MRSP and MSSP were comparable (MIC50 and MIC90 = 1mg/L for both groups, p = 0.317); overall, 49 isolates had MIC = 1 mg/L and one had MIC = 0.5 mg/L. The relatively low MICs obtained in this study are likely to be exceeded by topical therapy and thus further clinical evaluation of clotrimazole use in canine superficial pyoderma and otitis externa caused by MRSP and MSSP is now warranted

Inhomogeneous reionization and the polarization of the cosmic microwave background

In a universe with inhomogeneous reionization, the ionized patches create a second order signal in the cosmic microwave background polarization anisotropy. This signal originates in the coupling of the free electron fluctuation to the quadruple moment of the temperature anisotropy. We examine the contribution from a simple inhomogeneous reionization model and find that the signal from such a process is below the detectable limits of the Planck Surveyor mission. However t he signal is above the fundamental uncertainty limit from cosmic variance, so th at a future detection with a high accuracy experiment on sub-arcminute scales is possible.Comment: 10 pages, 2 eps figures, final version accepted for publication in ApJ Letter

Application of XFaster power spectrum and likelihood estimator to Planck

We develop the XFaster Cosmic Microwave Background (CMB) temperature and polarization anisotropy power spectrum and likelihood technique for the Planck CMB satellite mission. We give an overview of this estimator and its current implementation and present the results of applying this algorithm to simulated Planck data. We show that it can accurately extract the power spectrum of Planck data for the high-l multipoles range. We compare the XFaster approximation for the likelihood to other high-l likelihood approximations such as Gaussian and Offset Lognormal and a low-l pixel-based likelihood. We show that the XFaster likelihood is not only accurate at high-l, but also performs well at moderately low multipoles. We also present results for cosmological parameter Markov Chain Monte Carlo estimation with the XFaster likelihood. As long as the low-l polarization and temperature power are properly accounted for, e.g., by adding an adequate low-l likelihood ingredient, the input parameters are recovered to a high level of accuracy.Comment: 25 pages, 20 figures, updated to reflect published version: slightly extended account of XFaster technique, added improved plots and minor corrections. Accepted for publication in MNRA

Power Spectrum Estimators For Large CMB Datasets

Forthcoming high-resolution observations of the Cosmic Microwave Background (CMB) radiation will generate datasets many orders of magnitude larger than have been obtained to date. The size and complexity of such datasets presents a very serious challenge to analysing them with existing or anticipated computers. Here we present an investigation of the currently favored algorithm for obtaining the power spectrum from a sky-temperature map --- the quadratic estimator. We show that, whilst improving on direct evaluation of the likelihood function, current implementations still inherently scale as the equivalent of the cube of the number of pixels or worse, and demonstrate the critical importance of choosing the right implementation for a particular dataset.Comment: 8 pages LATEX, no figures, corrected misaligned columns in table

The Cosmic Microwave Background and Inflation Parameters

We review the currrent cosmic parameter determinations of relevance to inflation using the WMAP-1year, Boomerang, CBI, Acbar and other CMB data. The basic steps in the pipelines which determine the bandpowers from the raw data from which these estimations are made are summarized. We forecast how the precision is likely to improve with more years of WMAP in combination with future ground-based experiments and with Planck. We address whether the current data indicates strong breaking from uniform acceleration through the relatively small region of the inflaton potential that the CMB probes, manifest in the much-discussed running spectral index or in even more radical braking/breaking scenarios. Although some weak ``anomalies'' appear in the current data, the statistical case is not there. However increased precision, at the high multipole end and with polarization measurements, will significantly curtail current freedom.Comment: 24 pages, 10 figures, 2 tables, Int. J. Theor. Phys. 2004, ed. E. Verdaguer, "Peyresq Physics 8", "The Early Universe: Confronting theory with observations" (June 21-27, 2003

Arkansas Soybean Performance Tests 2008

Soybean cultivar performance tests are conducted each year in Arkansas by the University of Arkansas Division of Agriculture. The tests provide information to companies developing cultivars and/or marketing seed within the state, and aid the Arkansas Cooperative Extension Service in formulating cultivar recommendations for soybean producer

Arkansas Soybean Performance Tests 2011

Soybean variety and strain performance tests are conducted each year in Arkansas by the University of Arkansas System Division of Agriculture Arkansas Crop Variety Improvement Program. The tests provide information to companies developing varieties and/or marketing seed within the state, and aid the Arkansas Cooperative Extension Service in formulating variety recommendations for soybean producers

Arkansas Soybean Performance Tests 2007

Soybean cultivar performance tests are conducted each year in Arkansas by the University of Arkansas Division of Agriculture. The tests provide information to companies developing cultivars and/or marketing seed within the State, and aid the Arkansas Cooperative Extension Service in formulating cultivar recommendations for soybean producers

Arkansas Soybean Performance Tests 2012

Soybean variety and strain performance tests are conducted each year in Arkansas by the University of Arkansas System Division of Agriculture Arkansas Crop Variety Improvement Program. The tests provide information to companies developing varieties and/or marketing seed within the state, and aid the Arkansas Cooperative Extension Service in formulating variety recommendations for soybean producers