Ovarian profile of Wistar rats treated with Theobroa cacao extract.

The study was aimed at determining the effect of aqueous extract of Theobroma cacao on the histology of the ovary of female albino wistar rat. Twenty-four (24) adult wistar female rats weighting about 100- 160g were used for this research work and were divided into three (3) groups of eight (8) animals each. Group A; control, Group B; low dose and Group C; high dose with eight (8) animals in each group. Control group received vital feed; the low dose group was administered 240mgkg body weight of Theobroma cacao extract and the high dose group was administered 500mgkg body weight of the test substance. Extract was given daily by oral gavage method for twenty-one (21) days. Twenty-four hours after the last administration, all animals in each group were sacrificed under chloroform anesthesia. The ovaries were harvested, weighed and fixed in 10% buffered formalin for histological studies. Results showed that following administration of extract of Theoboma cacao at these doses, an insignificant decrease in organ weight was observed. Histological observation showed few follicles as well as loss of the substance of granulose cell this could possibly suggest decrease in production of sex steroids in the ovary.Keywords: Theobroma Cacao, Ovary, Histolog

Embed capacity development within all global health research

Summary box • All countries, including low- and middle-income countries, need robust health research capacity • The research capacity gap between global North and South is closing too slowly, and governments, funders, and academic institutions are not investing sufficiently to bridge this chasm • With two examples from collaborative research projects in sub-Saharan Africa, we illustrate how capacity development can be an integrated part of a joint research effort supported by all involved institutions • We advocate that research capacity development be valued as highly as evidence generation and be embedded in all global health researc

Embed capacity development within all global health research.

Summary box • All countries, including low- and middle-income countries, need robust health research capacity • The research capacity gap between global North and South is closing too slowly, and governments, funders, and academic institutions are not investing sufficiently to bridge this chasm • With two examples from collaborative research projects in sub-Saharan Africa, we illustrate how capacity development can be an integrated part of a joint research effort supported by all involved institutions • We advocate that research capacity development be valued as highly as evidence generation and be embedded in all global health researc