Geologic map, volcanic stratigraphy and structure of the Cabo de Gata volcanic zone, Betic-Rif orogen, SE Spain

The geologic map of the Neogene Cabo de Gata volcanic zone is presented together with a comprehensive volcanic stratigraphy and structure based on logging, correlation and mapping. Volcanic rocks are interbedded with sedimentary rocks throughout the Cabo de Gata volcanic zone. The volcano-sedimentary succession of Cabo de Gata has been divided into formations according to lithology, age, composition and stratigraphic position. The contacts between sedimentary units and volcanic units and between formations are unconformities. Sedimentary units were deposited during periods of volcanic repose. The depositional environment of volcanism in Cabo de Gata is characterized as shallow-water submarine to emergent based on lithofacies of volcanic rocks and on fossil content and sedimentary structures of sedimentary rocks. The eruptive style in Cabo de Gata is dominantly effusive, although small-volume explosive eruptions due to magma-water interaction processes and to explosions of lava flow and domes complexes occurred.Peer Reviewe

Glucose transport in brain and retina: implications in the management and complications of diabetes

Neural tissue is entirely dependent on glucose for normal metabolic activity. Since glucose stores in the brain and retina are negligible compared to glucose demand, metabolism in these tissues is dependent upon adequate glucose delivery from the systemic circulation. In the brain, the critical interface for glucose transport is at the brain capillary endothelial cells which comprise the blood–brain barrier (BBB). In the retina, transport occurs across the retinal capillary endothelial cells of the inner blood–retinal barrier (BRB) and the retinal pigment epithelium of the outer BRB. Because glucose transport across these barriers is mediated exclusively by the sodium-independent glucose transporter GLUT1, changes in endothelial glucose transport and GLUT1 abundance in the barriers of the brain and retina may have profound consequences on glucose delivery to these tissues and major implications in the development of two major diabetic complications, namely insulin-induced hypoglycemia and diabetic retinopathy. This review discusses the regulation of brain and retinal glucose transport and glucose transporter expression and considers the role of changes in glucose transporter expression in the development of two of the most devastating complications of long-standing diabetes mellitus and its management. Copyright © 1999 John Wiley & Sons, Ltd.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/35242/1/43_ftp.pd

Freshwater–saltwater interactions in a multilayer coastal aquifer (Ostia antica archaeological park, central Italy)

An integrated research approach consisting of hydrogeologic and geochemical methods was applied to a coastal aquifer in the Ostia Antica archaeological park, Roma, Italy, to describe freshwater–saltwater interactions. The archaeological park of Ostia Antica is located on the left bank of the Tevere River delta which developed on a morphologically depressed area. The water monitoring program included the installation of multiparametric probes in some wells inside the archaeological area, with continuous measurement of temperature, electrical conductivity, and water table level. Field surveys, water sampling, and major elements and bromide analyses were carried out on a seasonal basis in 2016. In order to understand the detailed stratigraphic setting of the area, three surface boreholes were accomplished. Two distinct circulations were identified during the dry season, with local interaction in the rainy period: an upper one within the archaeological cover, less saline and with recharge inland; and a deeper one in the alluvial materials of Tevere River, affected by salinization. Oxygen and carbon isotopic signature of calcite in the sediments extracted from the boreholes, along with major elements and Br concentration, allowed us to recognize the sources of salinity (mainly, local interaction with Roman salt pans and agricultural practices) and the processes of gas–water–rock interaction occurring in the area. All these inferences were confirmed and strengthened by PCA analysis of physicochemical data of groundwater

Cranial neuralgias

After a description of the anatomical-functional organization of the human trigeminal system, this chapter discusses the diagnostic and therapeutic options for trigeminal neuralgia (TN). In about 15% of patients who present with the clinical picture of typical TN, this is secondary to a major neurological disease, i.e., benign tumors of the cerebellopontine angle or multiple sclerosis. Some clinical criteria that were used to distinguish between classic and symptomatic TN, such as age at onset, involvement of the ophthalmic division, and responsiveness to medical treatment, are no longer considered reliable. It is recommended that all patients undergo magnetic resonance imaging (MRI) or trigeminal reflex recording. Carbamazepine (CBZ) and oxcarbazepine (OXC) are the first-choice medical treatments. Although other drugs may be effective, these are indicated when the patient cannot reach the therapeutic dosage of CBZ/OXC because of adverse events. Patients unresponsive to CBZ/OXC should be made aware of the available surgical interventions. Surgical procedures (including percutaneous lesions to the ganglion/root, microvascular decompression (MVD) in the posterior fossa, and gamma knife radiosurgery) are extremely efficacious with relatively few complications: each procedure has some advantage and disadvantage with respect to the other. Only MVD is a non-destructive procedure. This chapter also describes management of glossopharyngeal neuralgia, which is often misdiagnosed, and some other chronic pain conditions mediated by the trigeminal system, such as ophthalmic postherpetic neuralgia (PHN). © 2011 Elsevier B.V

CONTEXT BASED MESSAGE SELECTION STRATEGIES IN A BIOLOGICALLY INSPIRED AMBIENT INTELLIGENCE SYSTEM

The presented work is concerned with the wide research field of the Ambient Intelligence systems. These systems, also called Smart Spaces (SS), are designed to provide users with augmented services that do not need intensive and invasive interaction efforts. To obtain this, SS main functionalities are sensing, analyzing, deciding, acting / communicating. In the scope of this wide research field, this paper particularly deals with the analysis task through the study of a theoretical biologically inspired brain model and with the deciding and communicating tasks through the description of a rule enginebased message customization system. Virtual Characters (avatars) displayed on the user’s device represent the final front-end of the system. This choice is due to the high expressive capabilities guaranteed by this kind of communication means, able to enrich the message content with prosody, facial expressions, gestures and to make the communication more effective. Through examples and architecture diagrams, our solution for the problem of the context awareness-based parameterisation of the system reaction is explained