Cross-sections of large-angle hadron production in proton-- and pion--nucleus interactions VIII: aluminium nuclei and beam momenta from {\pm}3 GeV/c to {\pm}15 GeV/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% {\lambda}int thick stationary aluminium target, of proton and pion beams with momentum from \pm3 GeV/c to \pm15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on aluminium nuclei are compared with cross-sections on beryllium, carbon, copper, tin, tantalum and lead nuclei.Comment: 71 pages, 16 figures, 47 table

Cross-Sections of Large-Angle Hadron Production in Proton- and Pion-Nucleus Interactions V: Lead Nuclei and Beam Momenta from +/-3 Gev/c to +/-15 Gev/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary lead target, of proton and pion beams with momentum from +/-3 GeV/c to +/-15 GeV/c. Results are given for secondary particles with production angles 20 to 125 degrees. Cross-sections on lead nuclei are compared with cross-sections on beryllium, copper, and tantalum nuclei.Comment: 67 pages, 13 figures, 47 table

Health saving technologies in education: application efficiency problems

The steady tendency of deterioration of preschool children health, which has outlined recently, dictates a necessity of search of the ways, allowing to change this situation. Without family support it is impossible to solve improvement problems. The gymnastics in pairs promotes strengthening of motivational readiness of parents to participation in improving and ed-ucational processНаметившаяся в последнее время устойчивая тенденция ухудшения здоровья дошкольников диктует необходимость поиска путей, позволяющих изменить эту ситуацию. Без поддержки семьи решить задачи оздоровления невозможно. Парная гимнастика способствует усилению мотивационной готовности родителей к участию в оздоровительно-образовательном процесс

Cross-sections of large-angle hadron production in proton- and pion-nucleus interactions VI: carbon nuclei and beam momenta from \pm 3 GeV/c to \pm 15 GeV/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary carbon target, of proton and pion beams with momentum from \pm 3 GeV/c to \pm 15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on carbon nuclei are compared with cross-sections on beryllium, copper, tantalum and lead nuclei.Comment: 67 pages, 13 figure

Cross-Sections of Large-Angle Hadron Production in Proton- and Pion-Nucleus Interactions III: Tantalum Nuclei and Beam Momenta from +/-3 Gev/c to +/-15 Gev/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary tantalum target, of proton and pion beams with momentum from +/-3 GeV/c to +/-15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. They are of particular relevance for the optimization of the design parameters of the proton driver of a neutrino factory.Comment: 68 pages, 12 figures, corrections in v2: added 'HARP -CDP group' to author name, corrected two typos in Table 4 (last two p values for 65-90 degrees were all 0.972

Revisiting the 'LSND anomaly' II: critique of the data analysis

This paper, together with a preceding paper, questions the so-called 'LSND anomaly': a 3.8 sigma excess of antielectronneutrino interactions over standard backgrounds, observed by the LSND Collaboration in a beam dump experiment with 800 MeV protons. That excess has been interpreted as evidence for the antimuonneutrino to antielectronneutrino oscillation in the \Deltam2 range from 0.2 eV2 to 2 eV2. Such a \Deltam2 range is incompatible with the widely accepted model of oscillations between three light neutrino species and would require the existence of at least one light 'sterile' neutrino. In a preceding paper, it was concluded that the estimates of standard backgrounds must be significantly increased. In this paper, the LSND Collaboration's estimate of the number of antielectronneutrino interactions followed by neutron capture, and of its error, is questioned. The overall conclusion is that the significance of the 'LSND anomaly' is not larger than 2.3 sigma.Comment: 30 pages, 16 figures, 6 table

GAPDH binders as potential drugs for the therapy of polyglutamine diseases: Design of a new screening assay

AbstractProteins with long polyglutamine repeats form a complex with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which enhances aggregation and cytotoxicity in models of Huntington disease. The aim of this study was to develop a novel assay for the screening of anti-aggregation compounds with a focus on the aggregation-promoting capacity of GAPDH. The assay includes a pure Q58 polyglutamine fragment, GAPDH, and a transglutaminase that links the two proteins. The feasibility of the new assay was verified using two GAPDH binders, hydroxynonenal and −(−)deprenyl, and the benzothiazole derivative PGL-135 which exhibits anti-aggregation effect. All three substances were shown to reduce aggregation and cytotoxicity in the cell and in the fly model of Spinocerebellar ataxia

Reply to 'Corrections to the HARP-CDP Analysis of the LSND Neutrino Oscillation Backgrounds'

The alleged mistakes in recent papers that reanalyze the backgrounds to the 'LSND anomaly' do not exist. We maintain our conclusion that the significance of the 'LSND anomaly' is not 3.8 sigma but not larger than 2.3 sigma.Comment: 3 page

Why the paper CERN-PH-EP-2009-015 (arXiv:0903.4762) is scientifically unacceptable

The paper CERN-PH-EP-2009-015 (arXiv:0903.4762) by A. Bagulya et al. violates standards of quality of work and scientific ethics on several counts. The paper contains assertions that contradict established detector physics. The paper falls short of proving the correctness of the authors' concepts and results. The paper ignores or quotes misleadingly pertinent published work. The paper ignores the fact that the authors' concepts and results have already been shown wrong in the published literature. The authors seem unaware that cross-section results from the 'HARP Collaboration' that are based on the paper's concepts and algorithms are in gross disagreement with the results of a second analysis of the same data, and with the results of other experiments.Comment: 8 pages, 3 figure

Cross-sections of large-angle hadron production in proton- and pion-nucleus interactions VII: tin nuclei and beam momenta from \pm3 GeV/c to \pm15 GeV/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary tin target, of proton and pion beams with momentum from \pm3 GeV/c to \pm15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on tin nuclei are compared with cross-sections on beryllium, carbon, copper, tantalum and lead nuclei.Comment: 68 pages, 13 figure