Cross-sections of large-angle hadron production in proton-- and pion--nucleus interactions VIII: aluminium nuclei and beam momenta from {\pm}3 GeV/c to {\pm}15 GeV/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% {\lambda}int thick stationary aluminium target, of proton and pion beams with momentum from \pm3 GeV/c to \pm15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on aluminium nuclei are compared with cross-sections on beryllium, carbon, copper, tin, tantalum and lead nuclei.Comment: 71 pages, 16 figures, 47 table

Health saving technologies in education: application efficiency problems

The steady tendency of deterioration of preschool children health, which has outlined recently, dictates a necessity of search of the ways, allowing to change this situation. Without family support it is impossible to solve improvement problems. The gymnastics in pairs promotes strengthening of motivational readiness of parents to participation in improving and ed-ucational processНаметившаяся в последнее время устойчивая тенденция ухудшения здоровья дошкольников диктует необходимость поиска путей, позволяющих изменить эту ситуацию. Без поддержки семьи решить задачи оздоровления невозможно. Парная гимнастика способствует усилению мотивационной готовности родителей к участию в оздоровительно-образовательном процесс

Cross-Sections of Large-Angle Hadron Production in Proton- and Pion-Nucleus Interactions V: Lead Nuclei and Beam Momenta from +/-3 Gev/c to +/-15 Gev/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary lead target, of proton and pion beams with momentum from +/-3 GeV/c to +/-15 GeV/c. Results are given for secondary particles with production angles 20 to 125 degrees. Cross-sections on lead nuclei are compared with cross-sections on beryllium, copper, and tantalum nuclei.Comment: 67 pages, 13 figures, 47 table

Cross-sections of large-angle hadron production in proton- and pion-nucleus interactions VI: carbon nuclei and beam momenta from \pm 3 GeV/c to \pm 15 GeV/c

We report on double-differential inclusive cross-sections of the production of secondary protons, charged pions, and deuterons, in the interactions with a 5% nuclear interaction length thick stationary carbon target, of proton and pion beams with momentum from \pm 3 GeV/c to \pm 15 GeV/c. Results are given for secondary particles with production angles between 20 and 125 degrees. Cross-sections on carbon nuclei are compared with cross-sections on beryllium, copper, tantalum and lead nuclei.Comment: 67 pages, 13 figure

The American aid to the Russian reforms at the end of the twentieth century

The importance of the studied problem is caused by the USA’s leading role in the development of modern world order and the economy, its influence in the international economic organizations. The article is aimed at revealing the reasons of choosing neoliberal strategy for Russian reforms, the amount and results of the American financial and technical aid to these reforms. The leading approach of researching this problem is the complex one. It allows finding out economic, internal political, geopolitical and cultural factors which influenced the implementation and the results of the American assistance to the Russian reforms. Authors draw a conclusion about considerable influence of the USA on domestic policy of Russia in the early nineties of the XX century. The amount and the content of the American financial and technical assistance to the Russian government are analyzed. Promises of massive financial aid from the international economic organizations and the USA were realized partially and much later, than it was necessary for economic transformations. The article’s content and conclusions can be used in other scientific works on American-Russian relations history, Modern history of Russia, during elaboration the effective strategy of reforms for the countries which are in a condition of a transitional economy. © 2016 Tarasova et al

INFLUENCE OF BUSINESS DIGITALIZATION ON THE OIL RECOVERY FACTOR AND IMPROVING THE EFFICIENCY OF THE OIL AND GAS COMPANIES ACTIVITY

Against the background of the decline structure of hydrocarbon reserves in Russia, the maintenance of a stable level of production and enhanced oil recovery at mature fields is associated with the introduction of technologies of the fourth industrial revolution (Industry 4.0). The real and possible impact of digitalization on the oil recovery factor and impact of the technological solutions on the development hard-to-recover reserves have been сonsidered in the article. Special attention has been paid to the transition to intellectual methods of management, within the framework of digitalization, which ensure the effective management for all company’s processes, provide objective and transparent information for making accurate and operational management decisions. To ensure a significant effect from the digital transformation of the industry, it is necessary to create favorable investment conditions, including government regulation and stimulation

Forming graduate students’ vision regarding pedagogical activity of a classical university professor

In the introduction it is stated that forming graduate students’ readiness for pedagogical activity is based on the methodology of the post-non-classical science, which allows to use qualitative research methods aimed at interpreting opinions, standpoints, values of the actors as legitimate “data” and to define understanding of pedagogical activity’s specifics and the key trends in the development of higher education. Theoretical analysisis dedicated to understanding the purpose and meaning of pedagogical activity of a university professor from the standpoint of holistic approach. The article analyses valuable, theoretical and technological components of activity. It is pointed out that pedagogical activity can be logically analysed as a type of activity aimed at certain pedagogical problems. Empirical analysis is built around describing research results within the framework of solving academic pedagogical tasks by graduate students of Saratov State National Research University within the framework of the course named “University-level Pedagogics”. The article presents the results of academic tasks performed by graduate students. Conclusion Graduate students working as teaching assistants and instructors showed greater psychological readiness to carry out teaching activities at university. On the one hand, a significant fraction of graduate students has virtually no experience in teaching and, due to this, has certain expectations of teaching practice; on the other hand, the empirical study results indicate that it is this category that is interested in working under conditions of changes in the digital environment and mastering new educational technologies

GAPDH binders as potential drugs for the therapy of polyglutamine diseases: Design of a new screening assay

AbstractProteins with long polyglutamine repeats form a complex with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which enhances aggregation and cytotoxicity in models of Huntington disease. The aim of this study was to develop a novel assay for the screening of anti-aggregation compounds with a focus on the aggregation-promoting capacity of GAPDH. The assay includes a pure Q58 polyglutamine fragment, GAPDH, and a transglutaminase that links the two proteins. The feasibility of the new assay was verified using two GAPDH binders, hydroxynonenal and −(−)deprenyl, and the benzothiazole derivative PGL-135 which exhibits anti-aggregation effect. All three substances were shown to reduce aggregation and cytotoxicity in the cell and in the fly model of Spinocerebellar ataxia