636 research outputs found
Determinants of Foreign Direct Investment in the Food-Processing Industry: A Comparative Analysis of Developed and Developing Economies
This paper analyzes the determinants of foreign direct investments by the U.S. food-processing industry in developed and developing countries. We find that market size, per-capita income, and trade openness significantly affect U.S. food-processing firmsÂ’' decisions to invest abroad, but their influence differs between developed and developing countries. Economic development is positively associated with FDI in developing countries but negatively associated in developed countries. Market size is a major determinant of FDI only in developed economies. Trade openness seems to be important for sales by U.S. foreign affiliates in both developed and developing countries and for exports to developed country markets.International Relations/Trade,
Single glycine deletion in COL7A1 acting as glycine substitution in dystrophic epidermolysis bullosa
Potential economic impacts from improving breastfeeding rates in the UK
This article has been made available through the Brunel Open Access Publishing Fund.RATIONALE: Studies suggest that increased breastfeeding rates can provide substantial financial savings, but the scale of such savings in the UK is not known. OBJECTIVE: To calculate potential cost savings attributable to increases in breastfeeding rates from the National Health Service perspective. DESIGN AND SETTINGS: Cost savings focussed on where evidence of health benefit is strongest: reductions in gastrointestinal and lower respiratory tract infections, acute otitis media in infants, necrotising enterocolitis in preterm babies and breast cancer (BC) in women. Savings were estimated using a seven-step framework in which an incidence-based disease model determined the number of cases that could have been avoided if breastfeeding rates were increased. Point estimates of cost savings were subject to a deterministic sensitivity analysis. RESULTS: Treating the four acute diseases in children costs the UK at least £89 million annually. The 2009-2010 value of lifetime costs of treating maternal BC is estimated at £959 million. Supporting mothers who are exclusively breast feeding at 1 week to continue breast feeding until 4 months can be expected to reduce the incidence of three childhood infectious diseases and save at least £11 million annually. Doubling the proportion of mothers currently breast feeding for 7-18 months in their lifetime is likely to reduce the incidence of maternal BC and save at least £31 million at 2009-2010 value. CONCLUSIONS: The economic impact of low breastfeeding rates is substantial. Investing in services that support women who want to breast feed for longer is potentially cost saving
Time of harvest affects United States-grown Aronia mitschurinii berry polyphenols, ◦Brix, and acidity
The goal of this study was to determine how the date of harvest impacts the quality characteristics of Aronia mitschurinii (A. K. Skvortsov and Maitul.) ‘Viking’ and ‘Galicjanka’ berries. Aronia berries were collected from farms in the Midwestern and Northeastern United States over seven weeks of harvest during 2018, 2019 and 2020. The berries were analyzed for total phenol, anthocyanins, proanthocyanins, sugar, and acid. Aronia berry composition modestly deviated between each year of the study. Berries harvested in 2018 had the highest total phenols and proanthocyanidins, both increasing in content from weeks 1–5 from 15.90 ± 3.15–19.65 mg gallic acid equivalents/g fw, a 24% increase, and 2.22 ± 0.40–2.94 mg (+)-catechin equivalents/g fw, a 32% increase, respectively. Berries harvested in 2019 had the lowest total phenol and proanthocyanidin levels and had increasing anthocyanins until week 4. In 2020, aronia berry proanthocyanidins differed from those in 2018 by having 38% lower levels after the 4th week. Across years, berries had increasing ◦Brix, ◦Brix: acid, and pH throughout the seven weeks of harvest. Additionally, all years had slight, but statistically insignificant decreases in acidity over the harvest period. Moreover, analysis from berries collected in 2019 suggests no significant difference in quality factors between Viking and Galicjanka aronia cultivars. In conclusion, aronia berry total phenols, proanthocyanidins, pH, and berry size can be significantly affected by the growing year and time of harvest. Acidity was impacted more by growing year than harvest week. In contrast, anthocyanins and ◦Brix were consistent between years, but influenced considerably by the week of harvest
Cannabinoid use and effects in patients with epidermolysis bullosa:an international cross-sectional survey study
Abstract Background Epidermolysis bullosa (EB) patient anecdotes and case reports indicate that cannabinoid-based medicines (CBMs) may alleviate pain and pruritus and improve wound healing. CBM use has not been characterized in the EB patient population. Objectives To evaluate CBM use among EB patients, including CBM types, effects on symptoms (e.g., pain and pruritus), disease process (e.g., blistering, wounds, and inflammation), well-being (e.g., sleep, appetite) and concomitant medications. Methods English-speaking EB patients or caregivers completed an online international, anonymous, cross-sectional survey regarding CBM use. Respondents reported the types of CBMs, subsequent effects including perceived EB symptom alteration, changes in medication use, and side effects. Results Seventy-one EB patients from five continents reported using or having used CBMs to treat their EB. Missing question responses ranged between 0 (0%) and 33 (46%). Most used more than one CBM preparation (mean: 2.4 ± 1.5) and route of administration (mean: 2.1 ± 1.1). Topical and ingested were the most common routes. Pain and pruritus were reported retrospectively to decrease by 3 points (scale: 0–10; p < 0.001 for both) after CBM use. Most reported that CBM use improved their overall EB symptoms (95%), pain (94%), pruritus (91%) and wound healing (81%). Most participants (79%) reported decreased use of pain medications. The most common side-effect was dry mouth (44%). Conclusions CBMs improve the perception of pain, pruritus, wound healing, and well-being in EB patients and reduced concomitant medication use. Nevertheless, a direct relation between the use of CBMs and reduction of the above-mentioned symptoms cannot be proven by these data. Therefore, future controlled studies using pharmaceutically standardised CBM preparations in EB are warranted to delineate the risks and benefits of CBMs
A qualitative study of the experiences and expectations of women receiving in-patient postnatal care in one English maternity unit
Background Studies consistently highlight in-patient postnatal care as the area of maternity care women are least satisfied with. As part of a quality improvement study to promote a continuum of care from the birthing room to discharge home from hospital, we explored women’s expectations and experiences of current inpatient care. Methods For this part of the study, qualitative data from semi-structured interviews were transcribed and analysed using content analyses to identify issues and concepts. Women were recruited from two postnatal wards in one large maternity unit in the South of England, with around 6,000 births a year. Results Twenty women, who had a vaginal or caesarean birth, were interviewed on the postnatal ward. Identified themes included; the impact of the ward environment; the impact of the attitude of staff; quality and level of support for breastfeeding; unmet information needs; and women’s low expectations of hospital based postnatal care. Findings informed revision to the content and planning of in-patient postnatal care, results of which will be reported elsewhere. Conclusions Women’s responses highlighted several areas where changes could be implemented. Staff should be aware that how they inter-act with women could make a difference to care as a positive or negative experience. The lack of support and inconsistent advice on breastfeeding highlights that units need to consider how individual staff communicate information to women. Units need to address how and when information on practical aspects of infant care is provided if women and their partners are to feel confident on the woman’s transfer home from hospital
Exchange Effects in the Invar Hardening: as a test case
An increase of the critical resolved shear stress of Invar alloys (Invar
hardening) with a lowering temperature is explained. The effect is caused by a
growth of the exchange interaction between dangling -electron states of
dislocation cores and paramagnetic obstacles (e.g., Ni atoms in FeNi alloys)
which occurs below the Curie temperature. The spins of the two electrons align
along the magnetization due to the exchange interaction with the surrounding
atoms of the ferromagnetic. The exchange interaction between the dislocations
and obstacles is enhanced in Invars due to a strong growth of the magnetic
moments of atoms under the action of elastic strains near the dislocation
cores. Parameters characterizing the exchange interaction are determined for
the case of the FeNi Invar. The influence of the internal
magnetic field on the dislocation detachment from the obstacles is taken into
account. The obtained temperature dependence of the critical resolved shear
stress in the FeNi Invar agrees well with the available
experimental data. Experiments facilitating a further check of the theoretical
model are suggested.Comment: 8 pages, 2 figure
Revising acute care systems and processes to improve breastfeeding and maternal postnatal health: a pre and post intervention study in one English maternity unit
Background
Most women in the UK give birth in a hospital labour ward, following which they are
transferred to a postnatal ward and discharged home within 24 to 48 hours of the birth.
Despite policy and guideline recommendations to support planned, effective postnatal care,
national surveys of women’s views of maternity care have consistently found in-patient
postnatal care, including support for breastfeeding, is poorly rated.
Methods
Using a Continuous Quality Improvement approach, routine antenatal, intrapartum and
postnatal care systems and processes were revised to support implementation of evidence
based postnatal practice. To identify if implementation of a multi-faceted QI intervention
impacted on outcomes, data on breastfeeding initiation and duration, maternal health and
women’s views of care, were collected in a pre and post intervention longitudinal survey.
Primary outcomes included initiation, overall duration and duration of exclusive
breastfeeding. Secondary outcomes included maternal morbidity, experiences and satisfaction
with care. As most outcomes of interest were measured on a nominal scale, these were
compared pre and post intervention using logistic regression.
Results
Data were obtained on 741/1160 (64%) women at 10 days post-birth and 616 (54%) at 3
months post-birth pre-intervention, and 725/1153 (63%) and 575 (50%) respectively postintervention.
Post intervention there were statistically significant differences in the initiation
(p = 0.050), duration of any breastfeeding (p = 0.020) and duration of exclusive breastfeeding
to 10 days (p = 0.038) and duration of any breastfeeding to three months (p = 0.016). Post
intervention, women were less likely to report physical morbidity within the first 10 days of
birth, and were more positive about their in-patient care.
Conclusions
It is possible to improve outcomes of routine in-patient care within current resources through
continuous quality improvement
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