844 research outputs found
Supersolid phases of light in extended Jaynes-Cummings-Hubbard systems
Jaynes-Cummings-Hubbard lattices provide unique properties for the study of
correlated phases as they exhibit convenient state preparation and measurement,
as well as "in situ" tuning of parameters. We show how to realize charge
density and supersolid phases in Jaynes-Cummings-Hubbard lattices in the
presence of long-range interactions. The long-range interactions are realized
by the consideration of Rydberg states in coupled atom-cavity systems and the
introduction of additional capacitive couplings in quantum-electrodynamics
circuits. We demonstrate the emergence of supersolid and checkerboard solid
phases, for calculations which take into account nearest neighbour couplings,
through a mean-field decoupling.Comment: 9 pages with 6 figures, accepted for publication in Physical Review
High performance microprocessor system for eddy current defectoscope measurement signal processing
This article shows principles of development of the eddy current defectoscope data acquisition system. It describes goals of development of this system and main requirements for its characteristics. Also on basis of these requirements possible implementation of the device was suggested
94/Międzybłoniak opłucnej – diagnostyka i leczenie w materiale Centrum
Celem pracyjest prezentacja wyników leczenia chorych na międzybłoniaka opłucnej [MO] leczonych w latach 1965–2001 oraz ocena roli radioterapii w zapobieganiu niepowodzeniom miejscowym.Materiał i metodyW latach 1965–2001 w Centrum Onkologii w Krakowie leczono 75 chorych z powodu [MO]. Analizą objęto grupę 34 chorych leczonych od 1991 roku, u których postępowanie diagnostyczne i terapeutyczne było jednolite. U wszystkich chorych zastosowano leczenie operacyjne, które u 7 chorych miało charakter radykalny (pleuro-pericardio-diaphra-gmo-pneumonectomia). Pooperacyjna radioterapia zastosowana była u 23 chorych, z czego 14 chorych (61%) napromienianych było wiązką mieszaną fotonowo-elektronową. Zakres dawki podanej na teren jamy opłucnej wynosił od 45 do 55 Gy. W oszacowaniu odsetków przeżyć 1, 2 i 3-letnich zastosowano metodę Kaplana-Meiera. Wyniki uzyskane w grupie leczonej od 1991 roku porównano z wynikami leczenia grupy chorych leczonych w latach 1965–1990.Wyniki i wnioskiW analizowej grupie uzyskano nastęujące odsetki przeżyć: 1-rocznych 52.9%, 2-letnich 26.5%, 3-letnich 6.6%. Tolerancja leczenia była dobra. Stwierdzono, że wyniki te są lepsze w stosunku do grupy chorych leczonych do 1991 r. Różnice te dotyczą okresu 2 lat po zakończeniu leczenia. Zastosowanie u chorych na [MO] mieszanej wiązki fotonowoelektronowej pozwala na uzyskanie stosunkowo dobrych wyników leczenia przy dobrej tolerancji leczenia przez tych chorych
Новые методы получения и биологически активные свойства Пиоцианина
Пиоцианин обладает противомикробной, противогрибковой и противоопухолевой активностью. Для изучения этих свойств и поиска дальнейшего применения пиоцианина, был увеличен выход пиоцианина с помощью оптимизации условий культивирования и оптимизации питательной среды.Pyocyanin has antimicrobial, antifungal and antitumor activity. To study these properties and search for further use of pyocyanin, the yield of pyocyanin was increased by optimizing cultivation conditions and optimizing the nutrient medium
Biosimilar G-CSF versus filgrastim and lenograstim in healthy unrelated volunteer hematopoietic stem cell donors
The World Marrow Donor Organization recommends original granulocyte-colony stimulating factor (G-CSF) for the mobilization of stem cells in healthy unrelated hematopoietic stem cell donors. We report the comparison of a biosimilar G-CSF (Zarzio) with two original G-CSFs (filgrastim and lenograstim) in mobilization in unrelated donors. We included data of 313 consecutive donors who were mobilized during the period from October 2014 to March 2016 at the Medical University of Warsaw. The primary endpoints of this study were the efficiency of CD34+ cell mobilization to the circulation and results of the first apheresis. The mean daily dose of G-CSF was 9.1 μg/kg for lenograstim, 9.8 μg/kg for biosimilar filgrastim, and 9.3 μg/kg for filgrastim (p < 0.001). The mean CD34+ cell number per microliter in the blood before the first apheresis was 111 for lenograstim, 119 for biosimilar filgrastim, and 124 for filgrastim (p = 0.354); the mean difference was even less significant when comparing CD34+ number per dose of G-CSF per kilogram (p = 0.787). Target doses of CD34+ cells were reached with one apheresis in 87% donors mobilized with lenograstim and in 93% donors mobilized with original and biosimilar filgrastim (p = 0.005). The mobilized apheresis outcomes (mean number of CD34+ cells/kg of donor collected during the first apheresis) was similar with lenograstim, biosimilar filgrastim, and filgrastim: 6.2 × 10⁶, 7.6 × 10⁶, and 7.3 × 10⁶, respectively, p = 0.06. There was no mobilization failure in any of the donors. Biosimilar G-CSF is as effective in the mobilization of hematopoietic stem cells in unrelated donors as original G-CSFs. Small and clinically irrelevant differences seen in the study can be attributed to differences in G-CSF dose and collection-related factors. Active safety surveillance concurrent to clinical use and reporting to donor outcome registry (e.g., EBMT donor outcome registry or WMDA SEAR/SPEAR) might help to evaluate the possible short- and long-term complications of biosimilar G-CSF
Сопоставительный анализ эффективности и надежности применения пластинчатых и кожухотрубных теплообменных аппаратов на ЗАО «Томский приборный завод»
Вследствие экономических санкций к России поставка импортного теплоэнергетического оборудования становится затруднительной. Поэтому требуется замена пластинчатых теплообменников на кожухотрубные, что подтверждает практическую значимость этой проблемы.Due to economic sanctions to Russia, the supply of imported heat and power equipment becomes difficult. Therefore, replacement of plate heat exchangers with shell-and-tube heat exchangers is required, which confirms the practical importance of this problem
Разработка технологии и проектирование участка сборки-сварки траверсы задней механизированной крепи МКЮ4У.56
Актуальность работы: в данной выпускной квалификационной работе производится проектирование участка сборки-сварки траверсы задней крепи механизированной МКЮ 4У.56.
Объектом исследования является процесс изготовления траверсы.
В результате данной работы следует получить производство с наибольшей степенью механизации и автоматизации повышающей производительность труда.Relevance of the work: in the final qualifying work is done tooling design and site assembly welding traverses back lining mechanized MKY 4U.56
As a result of this work should be obtained from producing the greatest degree of mechanization and automation increases productivity
Homogenizing GPS integrated water vapour time series: methodology and benchmarking the algorithms on synthetic datasets
We would like to thank the COST Action ES1206 GNSS4SWEC for financial support
Study on homogenization of synthetic GNSS-Retrieved IWV time series and its impact on trend estimates with autoregressive noise
Póster presentado en: EGU General Assembly celebrada del 23 al 28 de abril de 2017 en Viena, Austria.A synthetic benchmark dataset of Integrated Water Vapour (IWV) was created within the activity of “Data homogenisation” of sub-working group WG3 of COST ES1206 Action. The benchmark dataset was created basing on the analysis of IWV differences retrieved by Global Positioning System (GPS) International GNSS Service (IGS) stations using European Centre for Medium-Range Weather Forecats (ECMWF) reanalysis data (ERA-Interim). Having analysed a set of 120 series of IWV differences (ERAI-GPS) derived for IGS stations, we delivered parameters of a number of gaps and breaks for every certain station. Moreover, we estimated values of trends, significant seasonalities and character of residuals when deterministic model was removed. We tested five different noise models and found that a combination of white and autoregressive processes of first order describes the stochastic part with a good accuracy. Basing on this analysis, we performed Monte Carlo simulations of 25 years long data with two different types of noise: white as well as combination of white and autoregressive processes. We also added few strictly defined offsets, creating three variants of synthetic dataset: easy, less complicated and fully complicated. The synthetic dataset we present was used as a benchmark to test various statistical tools in terms of homogenisation task. In this research, we assess the impact of the noise model, trend and gaps on the performance of statistical methods to detect simulated change points
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