10 research outputs found
Attempted Synthesis & Antibacterial Properties of APT-6K Against NDM-1 K. Pneumoniae
NDM-1 K. pneumoniae is a highly resistant bacterial organism that is capable of causing debilitating nosocomial infections in immunocompromised patients. Only last-resort antibiotics--such as colistin--work against this organism. Therefore, new antibiotics are needed to help fight against these types of infections. APT-6K is a novel compound that was demonstrated to be effective against MRSA with nanomolar concentrations in a prior study. Novel methods of APT-6K synthesis and its testing for antibiotic effects against NDM-1 K. pneumoniae were attempted in this research. APT-6K synthesis was unsuccessful. Commercially-prepared APT-6K also did not demonstrate growth inhibition against NDM-1 K. pneumoniae nor against a wild-type K. pneumoniae. Suggestions for future research are discussed
AFIA Hosts Rice Run
Storyhttps://digitalcommons.andrews.edu/campus-news-images/1652/thumbnail.jp
The Student Movement Volume 105 Issue 11: A Symposium of Research: Students Share Capstone Scholarship
NEWS
Andrews University Choral Performs Chasing Away the Blues Concert, Jenae Rogers
Bump, Set, Spike: Players and Fans Enjoy Intramural Volleyball Games, Amanda Cho
Reaching Milestones: The Honors Poster Symposium, Elianna Srikureja
WEAAU Hosts Women\u27s History Month Vespers, Terika Williams
PULSE
Hello, Sunshine, Wambui Karanja
Study Spots, Gloria Oh
The Buchanan Revitalization Project, Interview by Alec Bofetiado
HUMANS
An Interview with This Year\u27s AUSA President: Kyara Samuels, Interviewed by Abigail Lee
Editor-in-Chief Spotlight, Interviewed by Brandi Seawood
Senior Spotlight: TJ Hunter, Alyssa Henriquez
ARTS & ENTERTAINMENT
Book Review: Becoming by Michelle Obama, Alannah Tjhatra
Contemporary Young Women Making an Impact: Maitreyi Ramakrishnan, Kaela McFadden
Creative Spotlight: Michael Davis, Interviewed by Pearl Parker
Nomadland, Hannah Cruse
IDEAS
Literature and Her Influences: A Women\u27s History Month Booklist, Abigail Lee
The Astounding Potential of mRNA Vaccines, Lyle Goulbourne
THE LAST WORD
Trouble with the Editors, Moriah McDonaldhttps://digitalcommons.andrews.edu/sm-105/1014/thumbnail.jp
The Student Movement Volume 105 Issue Issue 5: Artist Spotlight: Jel Tamayo
NEWS
Andrews University Transitions to Dynamic Campus, Taylor Uphus
ASIS Holds First Vespers of Fall 2020, Joelle Kim
Students Participate in Andrews University Vote Week, Caralynn Chan
The Andrews University Symphony Orchestra Performs Awakening Concert, Jenae Rogers
PULSE
How to Stay Eco-Friendly During the Pandemic, Gloria Oh
Paralleling the Hispanic and Filipino Cultural Experience, Alec Bofetiado
The GetApp Go-To Orders, Wambui Karanja
HUMANS
AU Athletics for the Year 2020-21, Interviewed by Fitz-Earl McKenzie II
Checking in with Honors: 2020-21 Plans, Interviewed by Terika Williams
Discussing Mental Health and the CTC with Dr. Judith Bernard-Fisher and Mindy Kissinger, Interviewed by Abigail Lee
ARTS & ENTERTAINMENT
Filipino Artist Spotlight: Jel Tamayo, Megan Napod
Noche Latina: A Night of Music, Poetry, Dance, and Culture, Megan Napod
Signal Boost, Monday by Evin-Nazya Musgrove
IDEAS
That\u27s Just Me , Evin N. Musgrove
Superspreader in Chief, Lyle Goulbourne
The Vice Presidential Debate, Alannah Tjhatrahttps://digitalcommons.andrews.edu/sm-105/1005/thumbnail.jp
The Student Movement Volume 105 Issue 3: Students Take Appling Break
NEWS
Reimagining Chapel through Pulse Groups, Jenae Rogers
Pacific Union College Students Evacuated After Glass Fire, Staff
Unidos Through Ethnicity, Caralynn Chan
PULSE
Fresh Air, Fresh Produce, Jessica Rim
Pumpkin Spice and Everything Nice, Wambui Karanja
Yo Tengo Hambre!: A Sample of Hispanic Cuisine, Interviewed by Alec Bofetiado
HUMANS
Diversity in the English Classroom, Interviewed by Alyssa Henriquez
Kyara Samuels on Panamanian Culture, Interviewed by Ben Lee
My Multicultural Experience: Eight Students Discuss The Impact of Hispanic Culture on Their Lives, Interviewed by Celeste Richardson
ARTS & ENTERTAINMENT
Hispanic & Latinx Show and Movie Recommendations!, Megan Napod
TikTok, Time\u27s Running Out, Joshua Deonarine
Zoey\u27s Extraordinary Playlist, Hannah Cruse
IDEAS
Conversations With Me, Evin N. Musgrove
Faith in Our Current Moment, Adoniah Simon
Remembering RBG Part 1: Legacy of the Supreme Court Justice, American Icon and Feminist Champion, Lyle Goulbourne
THE LAST WORD
Gaming and \u27The Guys\u27, Daniel Selfhttps://digitalcommons.andrews.edu/sm-105/1003/thumbnail.jp
The Student Movement Volume 105 Issue 10: One Dose Down, One to Go!: President Luxton Vaccinated
NEWS
Andrews University Holds Employee Awards Virtual Celebration, Jenae Rogers
New Life Hosts Black Like Me: Growing Up Black, Caralynn Chan
Texas Winter Storm Impacts Families of Students at Andrews, Taylor Uphus
The Red Cross Blood Drive Reveals Growing Shortage in Donor Participation, Amanda Cho
PULSE
Favorite Meals: Café Edition, Interviewed by Alec Bofetiado
The Wellness Column: Decluttering your Room and Mind, HeeYun Oh
The Wellness Column: Decluttering Your Room and Mind, Jessica Rim
HUMANS
AUSA Candidate Interviews, Interviewed by Abigail Lee
Freshman Spotlight: Rekha Isaac, Interviewed by Celeste Richardson
Trusting the Science, Interviewed by Pearl Parker
ARTS & ENTERTAINMENT
Creative Spotlight: Karla Torres, Interviewed by Megan Napod
Current Favorites: March, Megan Napod
Signal Boost: Canvas, Hannah Cruse
IDEAS
A Woman and Her God, Evin N. Musgrove
COVID-19 Updates: The Variants, the Vaccines, and Other News, Sung Been Han
Parler, QAnon, and the Freedom of Speech: What Should be Done?, Abigail Lee
THE LAST WORD
Taking Stock, Masy Domecillohttps://digitalcommons.andrews.edu/sm-105/1013/thumbnail.jp
The Student Movement Volume 105 Issue 8: Cardinals Remain Undefeated Despite Season Cancellation
NEWS
BSCF Holds Impact Vespers, Terika Williams
Chapel Service Celebrates Black History Month, Jenae Rogers
Game on Hold: Student-Athletes Hope for New Basketball Season, Amanda Cho
PULSE
Student Workers: Balancing Life, Work, and Academics, Interviewed by Alec Bofetiado
Study Break Recommendations, Masy Domecillo
Weekday Holiday: Reflections, Jessica Rim
HUMANS
Black Student Christian Forum: Black History Month Interview, Interviewed by Fitz-Earl McKenzie II
My Experience in COVID-19 Isolation: Edition Two, Interviewed by Brandi Seawood
Our Lost Season: An Interview with Cardinals Athletic Director Rob Gettys, Terika Williams
Student Missionary Spotlight, Interviewed by Alyssa Henriquez
ARTS & ENTERTAINMENT
A Brief History Of Black Creativity and Its Importance, Pearl Parker
Black Novelists You Should Know & Read, Alannah Tjhatra
Creative Spotlight: Autumn Goodman of AGOODIEES, Interviewed by Megan Napod
The Hill We Climb, Hannah Cruse
IDEAS
Choose Wisely, Evin N. Musgrove
Playing the Game of Stocks, Matthew Jarrard
THE LAST WORD
Halftime of Horrors: The Weeknd and Hedonism, Daniel Selfhttps://digitalcommons.andrews.edu/sm-105/1010/thumbnail.jp
The Student Movement Volume 105 Issue 9: Celebrating the Caribbean Impact on Black History
NEWS
AUSA and BSCF Host The Dating Game, Caralynn Chan
Honors Agape Worship Celebrates Beverly Matiko\u27s Service, Terika Williams
The Andrews University Wind Symphony Performs Stage & Screen Concert, Jenae Rogers
PULSE
Black History Month: Favorite Media, Interviews by Alec Bofetiado
Black History Month: The Modern Heritage of Culture, Wambui Karanja
Lunar New Year: A Reflection, Jessica Rim
The Slump, Masy Domecillo
HUMANS
February Freshman Spotlight, Alyssa Henriquez
Senior Spotlight: Brandi Seawood, Interviewed by Celeste Richardson
Updates on 2020-21 Graduation Ceremony, Interviewed by Fitz-Earl McKenzie II
ARTS & ENTERTAINMENT
Black Artists I Recommend, Hannah Cruse
Creative Spotlight: Be of Good Cheer with Itumeleng Gabasiane, Interviewed by Megan Napod
Tesla, To the Moon!, Joshua Deonarine
IDEAS
Harlem Jazz and Louis Armstrong: His Life and Impact, Sion Kim
How to be a Black Community Ally, Kavya Mohanram
The Plans and Hopes of the Biden Administration, Lyle Goulbourne
THE LAST WORD
The Mountain, The Tree and You, Adoniah Simonhttps://digitalcommons.andrews.edu/sm-105/1012/thumbnail.jp
The Student Movement Volume 105 Issue 16: Best of The Student Movement 2020-21
NEWS
Bump, Set, Spike: Players and Fans Enjoy Intramural Volleyball Games, Amanda Cho
One Year Later: Reflecting on the Changes at Andrews University Since COVID-19, Taylor Uphus
Tenth Annual Honors Church Service Reflects on Christian Stewardship, Elianna Srikureja
The Andrews University Symphony Orchestra Performs Awakening Concert, Jenae Rogers
WEAAU Hosts Women\u27s History Month Vespers, Terika Williams
PULSE
Fresh Air, Fresh Produce, Jessica Rim
How to Stay Eco-Friendly During the Pandemic, Gloria Oh
International Women\u27s Month: Lessons From My Mother, Wambui Karaja
Spring Birding, Interview by Masy Domecillo
The Buchanan Revitalization Projects, Interview by Alec Bofetiado
HUMANS
Interviewing Andrews University\u27s AAPI Students on Allyship, Interviewed by Abigail Lee
My Experience in COVID-19 Isolation: Edition Two, Interviewed by Brandi Seawood
Our Lost Season: An Interview with Cardinals Athletic Director Rob Gettys, Terika Williams
Teaching During COVID-19, Interviewed by Celeste Richardson
Trusting the Science, Interviewed by Pearl Parker
ARTS & ENTERTAINMENT
Black Novelists You Should Know & Read, Alannah Tjhatra
Contemporary Young Women Making an Impact: Maitreyi Ramakrishnan, Kaela McFadden
Creative Spotlight: Michael David, Interviewed by Pearl Parker
Signal Boost, Monday by Evin-Nazya Musgrove
IDEAS
Just This Once , Evin N. Musgrove
On Healing, Adoniah Simon
Parler, QAnon, and the Freedom of Speech: What Should be Done?, Abaigail Lee
Productivity Tips to Help You Get Smart Fast, Alannah Tjhatra
The Good, Kyara Samuels
THE LAST WORD
How Does it Change Us?, Daniel Self
THIS JUST IN!
A COVID Passport: Is it Realistic?, Matt Jarrard
Graduation Weekend Events Calendar
Prescott Khair Joins Center for Faith Engagement as New Associate Chaplin, Isabella Koh and Moriah McDonald
This Year I Learned..., Wambui Karanjahttps://digitalcommons.andrews.edu/sm-105/1020/thumbnail.jp
P-24 Attempted Synthesis & Antibacterial Pr operties of APT-6K Against NDM-1 K. pneumoniae
NDM-1 K. pneumoniae is a highly resistant bacterial organism that is capable of causing debilitating nosocomial infections in immunocompromised patients. Only “last-resort” antibiotics—such as colistin—work against this organism. Therefore, new antibiotics are needed to help fight against these types of infections. APT-6K is a novel compound that was demonstrated to be effective against MRSA with nanomolar concentrations in a prior study. Novel methods of APT-6K synthesis and its testing for antibiotic effects against NDM-1 K. pneumoniae were attempted in this research. However, APT-6K synthesis was unsuccessful. Commercially-prepared APT-6K also did not demonstrate growth inhibition against NDM-1 K. pneumoniae nor against a wild-type K. pneumoniae. Suggestions for future research are discussed