Ecologia de populações de porco monteiro no Pantanal do Brasil

O porco monteiro chegou ao Pantanal há cerca de dois séculos e, desde então, tem sido considerado como a principal espécie cinegética (de interesse para a caça) na região. Suas populações vivem livres na planície e independentes da atividade humana, exceto pelo manejo tradicional que age como fator de controle populacional dos rebanhos. Considerando que a espécie apresenta potencial para utilização econômica e que pode vir a compor a pauta de produtos com certificação de origem no Pantanal, informações sobre a ecologia das populações presentes na planície são estratégicas. Este artigo apresenta um apanhado sobre as informações disponíveis a respeito da espécie e discute aspectos da dinâmica de suas populações, com base em projeções obtidas utilizando-se o software VORTEX 9.6.bitstream/CPAP-2010/57340/1/DOC106.pd

Hepatitis with Fibrin-Ring Granulomas

Abstract : We describe a 66-year-old woman hospitalized with fever, fatigue and hepatopathy. In her medical history arterial hypertension (treated with propranolol and lisinopril), diabetes mellitus type 2 (no treatment before admission) and a gout arthropathy were noted wherefore a therapy with allopurinol 300 mg per day has been started 4 months before. Liver biopsy revealed fibrin-ring granulomas, compatible with allopurinolinduced hepatitis. Because of persistence of high fever after stopping allopurinol, steroids (1 mg/kg) were started. Under this treatment, she developed pancytopenia and fever. The bone marrow aspiration revealed Leishmania infantum. A second liver biopsy showed amastigotes and a disappearance of the granulomas. The history revealed a travel to Malta 2 years earlier. Despite adequate treatment with liposomal amphotericin B the patient deteriorated and finally died in septic shoc

Investigations on latent zoonoses in the context of the Swiss Swein 99 - project

Livestock producers in developed countries, such as pig producers, are facing the challenge to produce high quality products which satisfy their customers. Quality assurance programmes therefore are likely to become more important in the near future (Blaha, 1997). A prerequisite to the development of such programmes is the knowledge of animal health data, including zoonoses. In this context, an epidemiological study of the pig health and productivity in Switzerland, called Schwein 99 , has been initiated. This study has the overall objective to study the health and production profile of swine in a broad approach, where pigs are expected to be followed from birth to slaughter. Thus it will be carried out at three levels, i.e. at the breeding units, the fattening units and the abattoirs, respectively. This paper presents preliminary results from a pilot study carried out prior to the larger project to investigate the importance of selected zoonoses, Salmonella, Yersinia enterocolilica and Mycobacterium avium, in slaughtered healthy pigs

A Prospective Multicenter SPOG 2003 FN Study of Microbiologically Defined Infections in Pediatric Cancer Patients with Fever and Neutropenia.

BACKGROUND: Fever and neutropenia (FN) often complicate anticancer treatment and can be caused by potentially fatal infections. Knowledge of pathogen distribution is paramount for optimal patient management. METHODS: Microbiologically defined infections (MDI) in pediatric cancer patients presenting with FN by nonmyeloablative chemotherapy enrolled in a prospective multi-center study were analyzed. Effectiveness of empiric antibiotic therapy in FN episodes with bacteremia was assessed taking into consideration recently published treatment guidelines for pediatric patients with FN. RESULTS: MDI were identified in a minority (22%) of pediatric cancer patients with FN. In patients with, compared to without MDI, fever (median, 5 [IQR 3-8] vs. 2 [IQR1-3] days, p < 0.001) and hospitalization (10 [6-14] vs. 5 [3-8] days, p < 0.001) lasted longer, transfer to the intensive care unit was more likely (13 of 95 [14%] vs. 7 of 346 [2.0%], p < 0.001), and antibiotics were given longer (10 [7-14] vs. 5 [4-7], p < 0.001). Empiric antibiotic therapy in FN episodes with bacteremia was highly effective if not only intrinsic and reported antimicrobial susceptibilities were considered but the purposeful omission of coverage for coagulase negative staphylococci and enterococci was also taken into account (81% [95%CI 68 - 90] vs. 96.6% [95%CI 87 - 99.4], p = 0.004) CONCLUSIONS: MDI were identified in a minority of FN episodes but they significantly affected management and the clinical course of pediatric cancer patients. Compliance with published guidelines was associated with effectiveness of empiric antibiotic therapy in FN episodes with bacteremia

A dynamical chiral bag model

We study a dynamical chiral bag model, in which massless fermions are confined within an impenetrable but movable bag coupled to meson fields. The self-consistent motion of the bag is obtained by solving the equations of motion exactly assuming spherical symmetry. When the bag interacts with an external meson wave we find three different kinds of resonances: {\it fermionic}, {\it geometric}, and $\sigma$-resonances. We discuss the phenomenological implications of our results.Comment: Two columns, 11 pages, 9 figures. Submitted to Physical Review

Finite temperature calculations for the bulk properties of strange star using a many-body approach

We have considered a hot strange star matter, just after the collapse of a supernova, as a composition of strange, up and down quarks to calculate the bulk properties of this system at finite temperature with the density dependent bag constant. To parameterize the density dependent bag constant, we use our results for the lowest order constrained variational (LOCV) calculations of asymmetric nuclear matter. Our calculations for the structure properties of the strange star at different temperatures indicate that its maximum mass decreases by increasing the temperature. We have also compared our results with those of a fixed value of the bag constant. It can be seen that the density dependent bag constant leads to higher values of the maximum mass and radius for the strange star.Comment: 21 pages, 2 tables, 12 figures Astrophys. (2011) accepte

Chiral phase properties of finite size quark droplets in the Nambu--Jona-Lasinio model

Chiral phase properties of finite size hadronic systems are investigated within the Nambu--Jona-Lasinio model. Finite size effects are taken into account by making use of the multiple reflection expansion. We find that, for droplets with relatively small baryon numbers, chiral symmetry restoration is enhanced by the finite size effects. However the radius of the stable droplet does not change much, as compared to that without the multiple reflection expansion.Comment: RevTex4, 9 pages, 6 figures, to be published in Phys. Rev.

Soft-core hyperon-nucleon potentials

A new Nijmegen soft-core OBE potential model is presented for the low-energy YN interactions. Besides the results for the fit to the scattering data, which largely defines the model, we also present some applications to hypernuclear systems using the G-matrix method. An important innovation with respect to the original soft-core potential is the assignment of the cut-off masses for the baryon-baryon-meson (BBM) vertices in accordance with broken SU(3)$_F$, which serves to connect the NN and the YN channels. As a novel feature, we allow for medium strong breaking of the coupling constants, using the $^3P_0$ model with a Gell-Mann--Okubo hypercharge breaking for the BBM coupling. We present six hyperon-nucleon potentials which describe the available YN cross section data equally well, but which exhibit some differences on a more detailed level. The differences are constructed such that the models encompass a range of scattering lengths in the $\Sigma N$ and $\Lambda N$ channels. For the scalar-meson mixing angle we obtained values $\theta_S=37$ to 40 degrees, which points to almost ideal mixing angles for the scalar $q\bar{q}$ states. The G-matrix results indicate that the remarkably different spin-spin terms of the six potentials appear specifically in the energy spectra of $\Lambda$ hypernuclei.Comment: 37 pages, 4 figure

Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device

Sequencing the genomes of individual cells enables the direct determination of genetic heterogeneity amongst cells within a population. We have developed an injection-moulded valveless microfluidic device in which single cells from colorectal cancer derived cell lines (LS174T, LS180 and RKO) and fresh colorectal tumors have been individually trapped, their genomes extracted and prepared for sequencing using multiple displacement amplification (MDA). Ninety nine percent of the DNA sequences obtained mapped to a reference human genome, indicating that there was effectively no contamination of these samples from non-human sources. In addition, most of the reads are correctly paired, with a low percentage of singletons (0.17 ± 0.06%) and we obtain genome coverages approaching 90%. To achieve this high quality, our device design and process shows that amplification can be conducted in microliter volumes as long as the lysis is in sub-nanoliter volumes. Our data thus demonstrates that high quality whole genome sequencing of single cells can be achieved using a relatively simple, inexpensive and scalable device. Detection of genetic heterogeneity at the single cell level, as we have demonstrated for freshly obtained single cancer cells, could soon become available as a clinical tool to precisely match treatment with the properties of a patient's own tumor