86 research outputs found
Automatic Search for Photoacoustic Marker Using Automated Transrectal Ultrasound
Real-time transrectal ultrasound (TRUS) image guidance during robot-assisted
laparoscopic radical prostatectomy has the potential to enhance surgery
outcomes. Whether conventional or photoacoustic TRUS is used, the robotic
system and the TRUS must be registered to each other. Accurate registration can
be performed using photoacoustic (PA markers). However, this requires a manual
search by an assistant [19]. This paper introduces the first automatic search
for PA markers using a transrectal ultrasound robot. This effectively reduces
the challenges associated with the da Vinci-TRUS registration. This paper
investigated the performance of three search algorithms in simulation and
experiment: Weighted Average (WA), Golden Section Search (GSS), and Ternary
Search (TS). For validation, a surgical prostate scenario was mimicked and
various ex vivo tissues were tested. As a result, the WA algorithm can achieve
0.53 degree average error after 9 data acquisitions, while the TS and GSS
algorithm can achieve 0.29 degree and 0.48 degree average errors after 28 data
acquisitions.Comment: 13 pages, 9 figure
Arc-to-line frame registration method for ultrasound and photoacoustic image-guided intraoperative robot-assisted laparoscopic prostatectomy
Purpose: To achieve effective robot-assisted laparoscopic prostatectomy, the
integration of transrectal ultrasound (TRUS) imaging system which is the most
widely used imaging modelity in prostate imaging is essential. However, manual
manipulation of the ultrasound transducer during the procedure will
significantly interfere with the surgery. Therefore, we propose an image
co-registration algorithm based on a photoacoustic marker method, where the
ultrasound / photoacoustic (US/PA) images can be registered to the endoscopic
camera images to ultimately enable the TRUS transducer to automatically track
the surgical instrument Methods: An optimization-based algorithm is proposed to
co-register the images from the two different imaging modalities. The
principles of light propagation and an uncertainty in PM detection were assumed
in this algorithm to improve the stability and accuracy of the algorithm. The
algorithm is validated using the previously developed US/PA image-guided system
with a da Vinci surgical robot. Results: The target-registration-error (TRE) is
measured to evaluate the proposed algorithm. In both simulation and
experimental demonstration, the proposed algorithm achieved a sub-centimeter
accuracy which is acceptable in practical clinics. The result is also
comparable with our previous approach, and the proposed method can be
implemented with a normal white light stereo camera and doesn't require highly
accurate localization of the PM. Conclusion: The proposed frame registration
algorithm enabled a simple yet efficient integration of commercial US/PA
imaging system into laparoscopic surgical setting by leveraging the
characteristic properties of acoustic wave propagation and laser excitation,
contributing to automated US/PA image-guided surgical intervention
applications.Comment: 12 pages, 9 figure
Transcranial Recording of Electrophysiological Neural Activity in the Rodent Brain in vivo Using Functional Photoacoustic Imaging of Near-Infrared Voltage-Sensitive Dye
Ultrasound speckle detection using low order moments
Abstract — Speckle detection is essential in many areas of quantitative ultrasound. In this work, speckle is characterized with R=SNR and S=skewness of the amplitude of the ultrasound signal data A. Different powers of A can be used to calculate R and S. Prager et al. [1] proposed a method for finding the optimum power value, which then was further scrutinized [2]. We propose using two different powers of A in R and S, and perform a large number of computer simulations to find these optimal values. I
Ultrasound Elastography Using Multiple Images
Displacement estimation is an essential step for ultrasound elastography and numerous techniques have been proposed to improve its quality using two frames of ultrasound RF data. This paper introduces a technique for calculating a displacement field from three (or multiple) frames of ultrasound RF data. To calculate a displacement field using three images, we first derive constraints on variations of the displacement field with time using mechanics of materials. These constraints are then used to generate a regularized cost function that incorporates amplitude similarity of three ultrasound images and displacement continuity. We optimize the cost function in an expectation maximization (EM) framework. Iteratively reweighted least squares (IRLS) is used to minimize the effect of outliers. An alternative approach for utilizing multiple images is to only consider two frames at any time and sequentially calculate the strains, which are then accumulated. We formally show that, compared to using two images or accumulating strains, the new algorithm reduces the noise and eliminates ambiguities in displacement estimation. The displacement field is used to generate strain images for quasi-static elastography. Simulation, phantom experiments and in-vivo patient trials of imaging liver tumors and monitoring ablation therapy of liver cancer are presented for validation. We show that even with the challenging patient data, where it is likely to have one frame among the three that is not optimal for strain estimation, the introduction of physics-based prior as well as the simultaneous consideration of three images significantly improves the quality of strain images. Average values for strain images of two frames versus ElastMI are: 43 versus 73 for SNR (signal to noise ratio) in simulation data, 11 versus 15 fo
Iterative Most-Likely Point Registration (IMLP): A Robust Algorithm for Computing Optimal Shape Alignment
<div><p>We present a probabilistic registration algorithm that robustly solves the problem of rigid-body alignment between two shapes with high accuracy, by aptly modeling measurement noise in each shape, whether isotropic or anisotropic. For point-cloud shapes, the probabilistic framework additionally enables modeling locally-linear surface regions in the vicinity of each point to further improve registration accuracy. The proposed Iterative Most-Likely Point (IMLP) algorithm is formed as a variant of the popular Iterative Closest Point (ICP) algorithm, which iterates between point-correspondence and point-registration steps. IMLP’s probabilistic framework is used to incorporate a generalized noise model into both the correspondence and the registration phases of the algorithm, hence its name as a most-likely point method rather than a closest-point method. To efficiently compute the most-likely correspondences, we devise a novel search strategy based on a principal direction (PD)-tree search. We also propose a new approach to solve the generalized total-least-squares (GTLS) sub-problem of the registration phase, wherein the point correspondences are registered under a generalized noise model. Our GTLS approach has improved accuracy, efficiency, and stability compared to prior methods presented for this problem and offers a straightforward implementation using standard least squares. We evaluate the performance of IMLP relative to a large number of prior algorithms including ICP, a robust variant on ICP, Generalized ICP (GICP), and Coherent Point Drift (CPD), as well as drawing close comparison with the prior anisotropic registration methods of GTLS-ICP and A-ICP. The performance of IMLP is shown to be superior with respect to these algorithms over a wide range of noise conditions, outliers, and misalignments using both mesh and point-cloud representations of various shapes.</p></div
Virtual remote center of motion control for needle placement robots
Abstract. Surgical robots, including those with remote center of motion (RCM) mechanisms, have demonstrated utility in image-guided percutaneous needle placement procedures. However, widespread clinical application of these robots is hindered by not only complicated mechanical design but also the need for calibration and registration of the robot to the medical imager prior to each use. In response, we propose a Virtual RCM algorithm that requires only online tracking or registering the surgical tool to the imager, and a five degree-offreedom (DOF) robot comprised of three prismatic DOF and two rotational DOF. The robot can be unencoded, uncalibrated, and does not require preoperative registration. An incremental adaptive motion control cycle both guides the needle to the insertion point and orients it to align with the target. The robot executes RCM motion “virtually ” without having a physically constrained fulcrum point. The proof-of-concept prototype system achieved 0.78 mm translation and 0.78 degrees rotational accuracy (within the tracker accuracy), within 17 iterative steps (0.5-1secs)
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