The Phase Diagram and Spectrum of Gauge-Fixed Abelian Lattice Gauge Theory

We consider a lattice discretization of a covariantly gauge-fixed abelian gauge theory. The gauge fixing is part of the action defining the theory, and we study the phase diagram in detail. As there is no BRST symmetry on the lattice, counterterms are needed, and we construct those explicitly. We show that the proper adjustment of these counterterms drives the theory to a new type of phase transition, at which we recover a continuum theory of (free) photons. We present both numerical and (one-loop) perturbative results, and show that they are in good agreement near this phase transition. Since perturbation theory plays an important role, it is important to choose a discretization of the gauge-fixing action such that lattice perturbation theory is valid. Indeed, we find numerical evidence that lattice actions not satisfying this requirement do not lead to the desired continuum limit. While we do not consider fermions here, we argue that our results, in combination with previous work, provide very strong evidence that this new phase transition can be used to define abelian lattice chiral gauge theories.Comment: 42 pages, 30 figure

Effect of Gsk3 inhibitor CHIR99021 on aneuploidy levels in rat embryonic stem cells

Germline competent embryonic stem (ES) cells can serve as a tool to create genetically engineered rat strains used to elucidate gene function or provide disease models. In optimum culture conditions, ES cells are able to retain their pluripotent state. The type of components present and their concentration in ES cell culture media greatly influences characteristics of ES cells including the ability to maintain the cells in a pluripotent state. We routinely use 2i media containing inhibitors CHIR99021 and PD0325901 to culture rat ES cells. CHIR99021 specifically inhibits the Gsk3β pathway. We have found that the vendor source of CHIR99021 has a measurable influence on the level of aneuploidy seen over time as rat ES cells are passaged. Karyotyping of three different rat ES cell lines passaged multiple times showed increased aneuploidy when CHIR99021 from source B was used. Mass spectrometry analysis of this inhibitor showed the presence of unexpected synthetic small molecules, which might directly or indirectly cause increases in chromosome instability. Identifying these molecules could further understanding of their influence on chromosome stability and indicate how to improve synthesis of this media component to prevent deleterious effects in culture

Herschel-SPIRE, far-infrared properties of millimetre-bright and -faint radio galaxies

We present the first study of the far-infrared (FIR) properties of high-redshift, radio-selected ultraluminous infrared galaxies (ULIRGs) using deep observations obtained with the Spectral and Photometric Imaging Receiver (SPIRE) from the Herschel Multi-tiered Extragalactic Survey (HerMES). These galaxies span a large range of 850-μm fluxes from submillimetre-luminous ∼10 mJy sources (SCUBA galaxies) to ∼1.5 mJy from stacked SCUBA non-detections, thus likely representing a complete distribution of ULIRG spectral energy distributions (SEDs). From Keck spectroscopic surveys in the Lockman-North field we identified a sample of 31 submillimetre galaxies (SMGs) and 37 submillimetre-faint, optically faint radio galaxies (OFRGs), all with radio-inferred IR luminosities >10^(12) L_⊙. These galaxies were cross-identified with SPIRE 250-, 350- and 500-μm catalogues based on fluxes extracted at 24-μm positions in the SWIRE survey, yielding a sample of more than half of the galaxies well detected in at least two of the SPIRE bandpasses. By fitting greybody dust models to the SPIRE photometry together with SCUBA 850-μm measurements (for OFRGs, only 850-inline image upper limits), we infer dust temperatures and FIR luminosities. The OFRGs detected by SPIRE have median 〈T_d〉= 41 ± 5 K and the SMGs have 〈T_d〉= 34 ± 5 K, both in reasonable agreement with previous (pre-Herschel) estimates, reaffirming that the local FIR/radio correlation holds (at least for this subset of high-z ULIRGs) at high redshift (we measure 〈q_(IR)〉= 2.43 ± 0.21 using S_(IR) derived from greybody fit coupled with a power-law extrapolation to the 24 μm). Our observations first confirm that a substantial fraction of OFRGs exhibits large infrared luminosities corresponding to SFRs of ∼400 M_⊙ yr^−1. The SPIRE observations secondly confirm the higher dust temperatures for these OFRGs than similarly selected SMGs, consistent with early predictions of the submillimetre-faint radio populations. Our observations also clearly confirm the large infrared luminosities of most SMGs selected with S_(850 μm) > 5 mJy and radio and strong 24-μm detections, corresponding to SFRs of ∼700 M_⊙ yr^(−1)

MolLoc: a web tool for the local structural alignment of molecular surfaces

MolLoc stands for Molecular Local surface comparison, and is a web server for the structural comparison of molecular surfaces. Given two structures in PDB format, the user can compare their binding sites, cavities or any arbitrary residue selection. Moreover, the web server allows the comparison of a query structure with a list of structures. Each comparison produces a structural alignment that maximizes the extension of the superimposition of the surfaces, and returns the pairs of atoms with similar physicochemical properties that are close in space after the superimposition. Based on this subset of atoms sharing similar physicochemical properties a new rototranslation is derived that best superimposes them. MolLoc approach is both local and surface-oriented, and therefore it can be particularly useful when testing if molecules with different sequences and folds share any local surface similarity. The MolLoc web server is available at http://bcb.dei.unipd.it/MolLoc

A paradox of syntactic priming: why response tendencies show priming for passives, and response latencies show priming for actives

Speakers tend to repeat syntactic structures across sentences, a phenomenon called syntactic priming. Although it has been suggested that repeating syntactic structures should result in speeded responses, previous research has focused on effects in response tendencies. We investigated syntactic priming effects simultaneously in response tendencies and response latencies for active and passive transitive sentences in a picture description task. In Experiment 1, there were priming effects in response tendencies for passives and in response latencies for actives. However, when participants' pre-existing preference for actives was altered in Experiment 2, syntactic priming occurred for both actives and passives in response tendencies as well as in response latencies. This is the first investigation of the effects of structure frequency on both response tendencies and latencies in syntactic priming. We discuss the implications of these data for current theories of syntactic processing

Redshift Determination and CO Line Excitation Modeling for the Multiply Lensed Galaxy HLSW-01

We report on the redshift measurement and CO line excitation of HERMES J105751.1+573027 (HLSW-01), a strongly lensed submillimeter galaxy discovered in Herschel/SPIRE observations as part of the Herschel Multi-tiered Extragalactic Survey (HerMES). HLSW-01 is an ultra-luminous galaxy with an intrinsic far-infrared luminosity of L _(FIR) = 1.4 × 10^(13) L _⊙, and is lensed by a massive group of galaxies into at least four images with a total magnification of μ = 10.9 ± 0.7. With the 100 GHz instantaneous bandwidth of the Z-Spec instrument on the Caltech Submillimeter Observatory, we robustly identify a redshift of z = 2.958 ± 0.007 for this source, using the simultaneous detection of four CO emission lines (J = 7 → 6, J = 8 → 7, J = 9 → 8, and J = 10 → 9). Combining the measured line fluxes for these high-J transitions with the J = 1 → 0, J = 3 → 2, and J = 5 → 4 line fluxes measured with the Green Bank Telescope, the Combined Array for Research in Millimeter Astronomy, and the Plateau de Bure Interferometer, respectively, we model the physical properties of the molecular gas in this galaxy. We find that the full CO spectral line energy distribution is described well by warm, moderate-density gas with T _(kin) = 86-235 K and n_H_2 = (1.1-3.5)x10^3 cm^(–3). However, it is possible that the highest-J transitions are tracing a small fraction of very dense gas in molecular cloud cores, and two-component models that include a warm/dense molecular gas phase with T _(kin) ~ 200 K, n_H_2 ~ 10^5 cm^(–3) are also consistent with these data. Higher signal-to-noise measurements of the J _(up) ≥ 7 transitions with high spectral resolution, combined with high spatial resolution CO maps, are needed to improve our understanding of the gas excitation, morphology, and dynamics of this interesting high-redshift galaxy

Machine-Readable Privacy Certificates for Services

Privacy-aware processing of personal data on the web of services requires managing a number of issues arising both from the technical and the legal domain. Several approaches have been proposed to matching privacy requirements (on the clients side) and privacy guarantees (on the service provider side). Still, the assurance of effective data protection (when possible) relies on substantial human effort and exposes organizations to significant (non-)compliance risks. In this paper we put forward the idea that a privacy certification scheme producing and managing machine-readable artifacts in the form of privacy certificates can play an important role towards the solution of this problem. Digital privacy certificates represent the reasons why a privacy property holds for a service and describe the privacy measures supporting it. Also, privacy certificates can be used to automatically select services whose certificates match the client policies (privacy requirements). Our proposal relies on an evolution of the conceptual model developed in the Assert4Soa project and on a certificate format specifically tailored to represent privacy properties. To validate our approach, we present a worked-out instance showing how privacy property Retention-based unlinkability can be certified for a banking financial service.Comment: 20 pages, 6 figure

Non-detection of a pulsar-powered nebula in Puppis A, and implications for the nature of the radio-quiet neutron star RX J0822-4300

We report on a deep radio search for a pulsar wind nebula associated with the radio-quiet neutron star RX J0822-4300 in the supernova remnant Puppis A. The well-determined properties of Puppis A allow us to constrain the size of any nebula to less than 30 arcsec; however we find no evidence for such a source on any spatial scale up to 30 arcmin. These non-detections result in an upper limit on the radio luminosity of any pulsar-powered nebula which is three orders of magnitude below what would be expected if RX J0822-4300 was an energetic young radio pulsar beaming away from us, and cast doubt on a recent claim of X-ray pulsations from this source. The lack of a radio nebula leads us to conclude that RX J0822-4300 has properties very different from most young radio pulsars, and that it represents a distinct population which may be as numerous, or even more so, than radio pulsars.Comment: 5 pages, including 2 embedded EPS figures, uses emulateapj.sty. Accepted to ApJ Letters (minor changes made following referee's report

A Polarization Sensitive Bolometric Receiver for Observations of the Cosmic Microwave Background

We have developed a bolometric receiver that is intrinsically sensitive to linear polarization for the purpose of making measurements of the polarization of the cosmic microwave background radiation. The receiver consists of a pair of co-located silicon nitride micromesh absorbers which couple anisotropically to linearly polarized radiation through a corrugated waveguide structure. This system allows background limited, simultaneous measurement of the Stokes I and Q parameters over ~30% bandwidths at frequencies from ~60 to 600 GHz. Since both linear polarizations traverse identical optical paths from the sky to the point of detection, the susceptibility of the system to systematic effects is minimized. The amount of uncorrelated noise between the two polarization senses is limited to the quantum limit of thermal and photon shot noise, while drifts in the relative responsivity to orthogonal polarizations are limited to the effect of non-uniformity in the thin film deposition of the leads and the intrinsic thermistor properties. Devices using NTD Ge thermistors have achieved NEPs of 2•10^(-17) W/√Hz with 1/f knees below 100mHz at a base temperature of 270 mK. Numerical modelling of the structures has been used to optimize the bolometer geometry and coupling to optics. Comparisons of numerical results and experimental data are made. A description of how the quantities measured by the device can be interpreted in terms of the Stokes parameters is presented. The receiver developed for the Boomerang and Planck HFI focal planes is presented in detail

The AzTEC mm-Wavelength Camera

AzTEC is a mm-wavelength bolometric camera utilizing 144 silicon nitride micromesh detectors. Herein we describe the AzTEC instrument architecture and its use as an astronomical instrument. We report on several performance metrics measured during a three month observing campaign at the James Clerk Maxwell Telescope, and conclude with our plans for AzTEC as a facility instrument on the Large Millimeter Telescope.Comment: 13 pages, 15 figures, accepted for publication in Monthly Notice