Staying on Course: Three Year Results of the National Guard Youth ChalleNGe Evaluation

Evaluates the effectiveness of a quasi-military residential and mentoring program that aims to place high school dropouts in employment, education, or military service and improve outcomes including indicators of health, lifestyle, and delinquency

Psychiatric Problems and Cultural Transitions in Alaska

Demographic characteristics of 105 Alaska Native patients referred for psychiatric evaluation are reviewed. Reasons for the referral are discussed and the psychiatric findings according to the DSM-II classification of the American Psychiatric Association are summarized. Particular attention is paid to the socio-cultural environments from which the patients came. The patient population is dominated by women whose "career" seems to be distinctly different from that of the men in the sample. The pertinent psychological and anthropological literature is presented to give current conceptual models for understanding psychiatric problems in the cross-cultural framework

Eskimo Sleep Paralysis

Sleep paralysis is an essentially rare condition of unknown aetiology associated with both the narcolepsy-cataplexy syndrome and with psychological dissociative experiences. This supposedly rare condition seems to be well known to Alaska Eskimos, having Eskimo names, a traditional cause, and a method for treatment. Pertinent literature is reviewed on sleep paralysis, Eskimo personality dynamics, in particular the use of hysterical mechanisms, and traditional explanations for phenomena of this type including literature on shamanism. Suggestions are made for the clinical approach to patients in the cross-cultural setting

Automotive Intrusion Detection Based on Constant CAN Message Frequencies Across Vehicle Driving Modes

The modern automobile relies on numerous electronic control units communicating over the de facto standard of the controller area network (CAN) bus. This communication network was not developed with cybersecurity in mind. Many methods based on constant time intervals between messages have been proposed to address this lack of security issue with the CAN bus. However, these existing methods may struggle to handle variable time intervals between messages during transitions of vehicle driving modes. This paper proposes a simple and cost-effective method to ensure the security of the CAN bus that is based on constant message frequencies across vehicle driving modes. This proposed method does not require any modifications on the existing CAN bus and it is designed with the intent for efficient execution in platforms with very limited computational resources. Test results with the proposed method against two different vehicles and a frequency domain analysis are also presented in the paper

Survey of Automotive Controller Area Network Intrusion Detection Systems

Novel attacks continue to appear against in-vehicle networks due to the increasing complexity of heterogeneous software and hardware components used in vehicles. These new components introduce challenges when developing efficient and adaptable security mechanisms. Several intrusion detection systems (IDS) have been proposed to identify and protect in-vehicle networks against malicious activities. We describe the state-of-the-art intrusion detection methods for securing automotive networks, with special focus on the Controller Area Network (CAN). We provide a description of vulnerabilities, highlight threat models, identify known attack vectors present in CAN, and discuss the advantages and disadvantages of suggested solutions

THE PRODUCTION OF VESICULAR STOMATITIS VIRUS BY ANTIGEN- OR MITOGEN-STIMULATED LYMPHOCYTES AND CONTINUOUS LYMPHOBLASTOID LINES

A variety of lymphoid cell populations were examined in terms of their ability to replicate vesicular stomatitis virus (VSV), a lytic, RNA-containing virus maturing at the cell surface. The number of cells capable of producing VSV was estimated in terms of infectious centers by the virus plaque assay (VPA), and morphologically by electron microscopy (EM). The lymphoid cells examined in this study included: (a) lymph node cells from delayed hypersensitive guinea pigs stimulated by specific antigen, (b) mouse spleen cells activated by selective bone marrow-derived (B) cell and thymus derived (T) cell mitogens, and (c) cells of human and murine continuous lymphoblastoid or lymphoma lines. In unstimulated cultures of guinea pig lymph node cells there is a background of approximately 1 in 1,000 cells which produces VSV; in purified protein derivative (PPD)-stimulated cultures the number of cells producing virus was 1.6% in the VPA and 1.9% by EM. These cells were large lymphocytes with some morphological features of transformed lymphocytes but were not typical blast cells. A few macrophages were associated with virus in both stimulated and control cultures. These observations indicate that (a) cells responsive to antigens, as detected by a marker virus, were lymphocytes; (b) cells other than lymphocytes (macrophages) were capable of replicating VSV even without antigenic stimulation; and (c) the correlation of results obtained by VPA and morphologic examination was usually quite good. Of the total number of mouse spleen cells stimulated with concanavalin (Con A), a T cell mitogen, 4.5 (EM)–5.7% (VPA) were associated with VSV. These were characteristic transformed lymphocytes, similar to phytohemagglutinin (PHA)-stimulated human lymphocytes. In contrast Escherichia coli lipopolysaccharide (LPS)-treated mouse spleen cultures contained lower numbers of virus plaque-forming cells. The majority of such cells associated with virus displayed extensive rough endoplasmic reticulum. Two cultured murine lymphomas containing lymphocytes with the θ surface marker (L5178Y and EL-4) showed a 15–100-fold higher incidence of virus-producing cells than leukemias (L1210 and C57Bl/6) which did not carry this marker. Similarly, the L2C guinea pig leukemia, a known B cell leukemia, yielded a low percent of virus plaque-forming cells (<2%). However, MOPC-104, a plasma cell tumor presumed to be of B cell origin, was found to be an efficient virus producer. There was a wide variation in the efficiency of VSV replication among human lymphoblastoid lines. One line, Wil-2, produced 80% infectious centers after 24 h of exposure to VSV, and all cells were associated with virus at the EM level. The relationship between the virus-producing cells and different lymphocyte subpopulations as well as the efficiency of the two assays for studying virus-producing lymphocytes is discussed