486 research outputs found
Electric Switching of the Charge-Density-Wave and Normal Metallic Phases in Tantalum Disulfide Thin-Film Devices
We report on switching among three charge-density-wave phases - commensurate,
nearly commensurate, incommensurate - and the high-temperature normal metallic
phase in thin-film 1T-TaS2 devices induced by application of an in-plane
electric field. The electric switching among all phases has been achieved over
a wide temperature range, from 77 K to 400 K. The low-frequency electronic
noise spectroscopy has been used as an effective tool for monitoring the
transitions, particularly the switching from the incommensurate
charge-density-wave phase to the normal metal phase. The noise spectral density
exhibits sharp increases at the phase transition points, which correspond to
the step-like changes in resistivity. Assignment of the phases is consistent
with low-field resistivity measurements over the temperature range from 77 K to
600 K. Analysis of the experimental data and calculations of heat dissipation
suggest that Joule heating plays a dominant role in the electric-field induced
transitions in the tested 1T-TaS2 devices on Si/SiO2 substrates. The
possibility of electrical switching among four different phases of 1T-TaS2 is a
promising step toward nanoscale device applications. The results also
demonstrate the potential of noise spectroscopy for investigating and
identifying phase transitions in materials.Comment: 32 pages, 7 figure
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NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus.
Experience-dependent expression of immediate-early gene transcription factors (IEG-TFs) can transiently change the transcriptome of active neurons and initiate persistent changes in cellular function. However, the impact of IEG-TFs on circuit connectivity and function is poorly understood. We investigate the specificity with which the IEG-TF NPAS4 governs experience-dependent changes in inhibitory synaptic input onto CA1 pyramidal neurons (PNs). We show that novel sensory experience selectively enhances somatic inhibition mediated by cholecystokinin-expressing basket cells (CCKBCs) in an NPAS4-dependent manner. NPAS4 specifically increases the number of synapses made onto PNs by individual CCKBCs without altering synaptic properties. Additionally, we find that sensory experience-driven NPAS4 expression enhances depolarization-induced suppression of inhibition (DSI), a short-term form of cannabinoid-mediated plasticity expressed at CCKBC synapses. Our results indicate that CCKBC inputs are a major target of the NPAS4-dependent transcriptional program in PNs and that NPAS4 is an important regulator of plasticity mediated by endogenous cannabinoids
Legitimate to whom? The challenge of audience diversity and new venture legitimacy
We examine how entrepreneurs manage new venture legitimacy judgments across diverse audiences, so as to appear legitimate to the different audience groups that provide much needed financial resources for venture survival and growth. To do so, we first identify and describe the different mechanisms by which entrepreneurs can establish new venture legitimacy across diverse audiences. We then account for the institutional logics that characterize different new venture audience groups, and use this as a basis for uncovering how and why the legitimacy criteria for a new technology venture may vary depending on the audience. We then consider how leaders of entrepreneurial ventures may use framing as a means to manage legitimacy judgments across various audiences, and thereby improve their chances of accessing critical financial resources for venture survival and growth
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