1,401 research outputs found
Higher Responsiveness of Pattern Generation Circuitry to Sensory Stimulation in Healthy Humans Is Associated with a Larger Hoffmann Reflex
Simple Summary Individual differences in the sensorimotor circuitry play an important role for understanding the nature of behavioral variability and developing personalized therapies. While the spinal network likely requires relatively rigid organization, it becomes increasingly evident that adaptability and inter-individual variability in the functioning of the neuronal circuitry is present not only in the brain but also in the spinal cord. In this study we investigated the relationship between the excitability of pattern generation circuitry and segmental reflexes in healthy humans. We found that the high individual responsiveness of pattern generation circuitries to tonic sensory input in both the upper and lower limbs was related to larger H-reflexes. The results provide further evidence for the importance of physiologically relevant assessments of spinal cord neuromodulation and the individual physiological state of reflex pathways. The state and excitability of pattern generators are attracting the increasing interest of neurophysiologists and clinicians for understanding the mechanisms of the rhythmogenesis and neuromodulation of the human spinal cord. It has been previously shown that tonic sensory stimulation can elicit non-voluntary stepping-like movements in non-injured subjects when their limbs were placed in a gravity-neutral unloading apparatus. However, large individual differences in responsiveness to such stimuli were observed, so that the effects of sensory neuromodulation manifest only in some of the subjects. Given that spinal reflexes are an integral part of the neuronal circuitry, here we investigated the extent to which spinal pattern generation excitability in response to the vibrostimulation of muscle proprioceptors can be related to the H-reflex magnitude, in both the lower and upper limbs. For the H-reflex measurements, three conditions were used: stationary limbs, voluntary limb movement and passive limb movement. The results showed that the H-reflex was considerably higher in the group of participants who demonstrated non-voluntary rhythmic responses than it was in the participants who did not demonstrate them. Our findings are consistent with the idea that spinal reflex measurements play important roles in assessing the rhythmogenesis of the spinal cord
A multi-wavelength polarimetric study of the blazar CTA 102 during a Gamma-ray flare in 2012
We perform a multi-wavelength polarimetric study of the quasar CTA 102 during
an extraordinarily bright -ray outburst detected by the {\it Fermi}
Large Area Telescope in September-October 2012 when the source reached a flux
of F photons cm s.
At the same time the source displayed an unprecedented optical and NIR
outburst. We study the evolution of the parsec scale jet with ultra-high
angular resolution through a sequence of 80 total and polarized intensity Very
Long Baseline Array images at 43 GHz, covering the observing period from June
2007 to June 2014. We find that the -ray outburst is coincident with
flares at all the other frequencies and is related to the passage of a new
superluminal knot through the radio core. The powerful -ray emission is
associated with a change in direction of the jet, which became oriented more
closely to our line of sight (1.2) during the ejection of
the knot and the -ray outburst. During the flare, the optical polarized
emission displays intra-day variability and a clear clockwise rotation of
EVPAs, which we associate with the path followed by the knot as it moves along
helical magnetic field lines, although a random walk of the EVPA caused by a
turbulent magnetic field cannot be ruled out. We locate the -ray
outburst a short distance downstream of the radio core, parsecs from the black
hole. This suggests that synchrotron self-Compton scattering of near-infrared
to ultraviolet photons is the probable mechanism for the -ray
production.Comment: Accepted for publication in The Astrophysical Journa
Probing the Inner Jet of the Quasar PKS 1510-089 with Multi-waveband Monitoring during Strong Gamma-ray Activity
We present results from monitoring the multi-waveband flux, linear
polarization, and parsec-scale structure of the quasar PKS 1510-089,
concentrating on eight major gamma-ray flares that occurred during the interval
2009.0-2009.5. The gamma-ray peaks were essentially simultaneous with maxima at
optical wavelengths, although the flux ratio of the two wavebands varied by an
order of magnitude. The optical polarization vector rotated by 720 degrees
during a 5-day period encompassing six of these flares. This culminated in a
very bright, roughly 1 day, optical and gamma-ray flare as a bright knot of
emission passed through the highest-intensity, stationary feature (the "core")
seen in 43 GHz Very Long Baseline Array images. The knot continued to propagate
down the jet at an apparent speed of 22c and emit strongly at gamma-ray
energies as a months-long X-ray/radio outburst intensified. We interpret these
events as the result of the knot following a spiral path through a mainly
toroidal magnetic field pattern in the acceleration and collimation zone of the
jet, after which it passes through a standing shock in the 43 GHz core and then
continues downstream. In this picture, the rapid gamma-ray flares result from
scattering of infrared seed photons from a relatively slow sheath of the jet as
well as from optical synchrotron radiation in the faster spine. The 2006-2009.7
radio and X-ray flux variations are correlated at very high significance; we
conclude that the X-rays are mainly from inverse Compton scattering of infrared
seed photons by 20-40 MeV electrons.Comment: 10 pages of text + 5 figures, to be published in Astrophysical
Journal Letters in 201
Flaring Behavior of the Quasar 3C~454.3 across the Electromagnetic Spectrum
We analyze the behavior of the parsec-scale jet of the quasar 3C~454.3 during
pronounced flaring activity in 2005-2008. Three major disturbances propagated
down the jet along different trajectories with Lorentz factors 10. The
disturbances show a clear connection with millimeter-wave outbursts, in 2005
May/June, 2007 July, and 2007 December. High-amplitude optical events in the
-band light curve precede peaks of the millimeter-wave outbursts by 15-50
days. Each optical outburst is accompanied by an increase in X-ray activity. We
associate the optical outbursts with propagation of the superluminal knots and
derive the location of sites of energy dissipation in the form of radiation.
The most prominent and long-lasting of these, in 2005 May, occurred closer to
the black hole, while the outbursts with a shorter duration in 2005 Autumn and
in 2007 might be connected with the passage of a disturbance through the
millimeter-wave core of the jet. The optical outbursts, which coincide with the
passage of superluminal radio knots through the core, are accompanied by
systematic rotation of the position angle of optical linear polarization. Such
rotation appears to be a common feature during the early stages of flares in
blazars. We find correlations between optical variations and those at X-ray and
-ray energies. We conclude that the emergence of a superluminal knot
from the core yields a series of optical and high-energy outbursts, and that
the mm-wave core lies at the end of the jet's acceleration and collimation
zone.Comment: 57 pages, 23 figures, 8 tables (submitted to ApJ
WALOP-South: A Four Camera One Shot Imaging Polarimeter for PASIPHAE Survey. Paper I -- Optical Design
The WALOP-South instrument will be mounted on the 1 m SAAO telescope in South
Africa as part of the PASIPHAE program to carry out a linear imaging
polarization survey of the Galactic polar regions in the optical band. Designed
to achieve polarimetric sensitivity of across a
arcminute field of view, it will be capable of measuring the Stokes parameters
I, q and u in a single exposure in the SDSS-r broadband and narrowband filters
between . For each measurement, four images of the
full field corresponding to linear polarization angles of 0 deg, 45 deg, 90 deg
and 135 deg in the instrument coordinate system will be created on four
detectors from which the Stokes parameters can be found using differential
photometry. In designing the optical system, major challenges included
correcting for the dispersion introduced by large split angle Wollaston Prisms
used as analysers as well as other aberrations from the entire field to obtain
imaging quality PSF at the detector. We present the optical design of the
WALOP-South instrument which overcomes these challenges and delivers near
seeing limited PSFs for the entire field of view.Comment: 31 pages, 18 Figures and 8 Tables. Accepted in the Journal of
Astronomical Telescopes, Instruments, and System
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