Discovery of a New Dusty B[e] Star in the Small Magellanic Cloud

We present new optical spectroscopic and archival Spitzer IRAC photometric observations of a B-type star in the SMC cluster NGC 346, NGC 346:KWBBe 200. We detect numerous Fe II, [O I], and [Fe II] lines, as well as strong P-Cygni profile H I emission lines in its optical spectrum. The star's near-IR color and optical to IR SED clearly indicate the presence of an infrared excess, consistent with the presence of gas and warm, T ~800 K, circumstellar dust. Based on a crude estimate of the star's luminosity and the observed spectroscopic line profile morphologies, we find that the star is likely to be a B-type supergiant. We suggest that NGC 346:KWBBe 200 is a newly discovered B[e] supergiant star, and represents the fifth such object to be identified in the SMC.Comment: 12 pages, accepted by Ap

NLTE Monte Carlo Radiative Transfer: I. The Thermal Properties of Keplerian Disks around Classical Be Stars

We present a 3-D NLTE Monte Carlo radiative transfer code that we use to study the temperature and ionization structure of Keplerian disks around Classical Be stars. The method we employ is largely similiar to the Monte Carlo transition probability method developed by Lucy. Here we present a simplification of his method that avoids the use of the macro atom concept. Our investigations of the temperature structure of Be star disks show that the disk temperature behavior is a hybrid between the behavior of Young Stellar Object (YSO) disks and Hot Star winds. The optically thick inner parts of Be star disks have temperatures that are similar to YSO disks, while the optically thin outer parts are like stellar winds. Thus, the temperature at the disk midplane initially drops, reaching a minimum at 3--5 stellar radii, after which it rises back to the optically thin radiative equilibrium temperature at large distances. On the other hand, the optically thin upper layers of the disk are approximately isothermal -- a behavior that is analogous to the hot upper layers of YSO disks. We also find that the disks are fully ionized, as expected, but there is an ionization minimum in the vicinity of the temperature minimum. Finally, we find that, despite the complex temperature structure, the infrared excess is well-approximated by an equivalent isothermal disk model whose temperature is about 60% of the stellar temperature. This is largely because, at long wavelengths, the effective photosphere of the disk is located in its isothermal regions.Comment: Accepted to Ap

Power to the people : evidence from a randomized field experiment of a community-based monitoring project in Uganda

This paper analyzes the importance of strengthening the relationship of accountability between health service providers and citizens for improving access to and quality of health care. How this is to be achieved, and whether it works, however, remain open questions. The paper presents a randomized field experiment on increasing community-based monitoring. As communities began to more extensively monitor the provider, both the quality and quantity of health service provision improved. One year into the program, there are large increases in utilization, significant weight-for-age z-score gains of infants, and markedly lower deaths among children. The findings on staff behavior suggest that the improvements in quality and quantity of health service delivery resulted from an increased effort by the staff to serve the community. Overall, the results suggest that community monitoring can play an important role in improving service delivery when traditional top-down supervision is ineffective.Health Monitoring&Evaluation,Housing&Human Habitats,Health Economics&Finance,Disease Control&Prevention,Health Systems Development&Reform

Few and Far Between: How HIV May Be Evading Antibody Avidity

No abstract

HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface

Transferrin receptor (TfR) is a dimeric cell surface protein that binds both the serum iron transport protein transferrin (Fe-Tf) and HFE, the protein mutated in patients with the iron overload disorder hereditary hemochromatosis. HFE and Fe-Tf can bind simultaneously to TfR to form a ternary complex, but HFE binding to TfR lowers the apparent affinity of the Fe-Tf/TfR interaction. This apparent affinity reduction could result from direct competition between HFE and Fe-Tf for their overlapping binding sites on each TfR polypeptide chain, from negative cooperativity, or from a combination of both. To explore the mechanism of the affinity reduction, we constructed a heterodimeric TfR that contains mutations such that one TfR chain binds only HFE and the other binds only Fe-Tf. Binding studies using a heterodimeric form of soluble TfR demonstrate that TfR does not exhibit cooperativity in heterotropic ligand binding, suggesting that some or all of the effects of HFE on iron homeostasis result from competition with Fe-Tf for TfR binding. Experiments using transfected cell lines demonstrate a physiological role for this competition in altering HFE trafficking patterns

The Role of Evolutionary Age and Metallicity in the Formation of Classical Be Circumstellar Disks II. Assessing the Evolutionary Nature of Candidate Disk Systems

(Abridged version) We present the first detailed imaging polarization observations of six SMC and six LMC clusters, known to have large populations of B-type stars which exhibit excess H-alpha emission, to constrain the evolutionary status of these stars and hence better establish links between the onset of disk formation in classical Be stars and cluster age and/or metallicity. The wavelength dependence of our intrinsic polarization data provides a diagnostic of the dominant and any secondary polarigenic agents present, enabling us to discriminate pure gas disk systems, i.e. classical Be stars, from composite gas plus dust disk systems, i.e. Herbig Ae/Be or B[e] stars. Our intrinsic polarization results, along with available near-IR color information, strongly supports the suggestion of Wisniewski et al. that classical Be stars are present in clusters of age 5-8 Myr, and contradict assertions that the Be phenomenon only develops in the second half of a B star's main sequence lifetime, i.e. no earlier than 10 Myr. Comparing the polarimetric properties of our dataset to a similar survey of Galactic classical Be stars, we find that the prevalence of polarimetric Balmer jump signatures decreases with metallicity. We speculate that these results might indicate that either it is more difficult to form large disk systems in low metallicity environments, or that the average disk temperature is higher in these low metallicity environments. We have characterized the polarimetric signatures of all candidate Be stars in our data sample and find ~25% are unlikely to arise from true classical Be star-disk systems.Comment: 30 pages, accepted by ApJ, emulateapj5 forma

Flight test results of the strapdown hexad inertial reference unit (SIRU). Volume 2: Test report

Results of flight tests of the Strapdown Inertial Reference Unit (SIRU) navigation system are presented. The fault tolerant SIRU navigation system features a redundant inertial sensor unit and dual computers. System software provides for detection and isolation of inertial sensor failures and continued operation in the event of failures. Flight test results include assessments of the system's navigational performance and fault tolerance. Performance shortcomings are analyzed