<span style="font-size:20.5pt;mso-bidi-font-size:14.5pt; font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">Alkaloids from the leaves of <i>Aberia caffra</i></span>

215-219<span style="font-size:14.5pt;mso-bidi-font-size:8.5pt; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">Two new alkaloids have been isolated from the leaves of Aberia caffra, and characterised as aberiamine N1<span style="font-size:11.5pt;mso-bidi-font-size:5.5pt;font-family:Arial;mso-fareast-font-family: " times="" new="" roman";mso-ansi-language:en-us;mso-fareast-language:en-us;="" mso-bidi-language:ar-sa"=""> <span style="font-size:14.5pt;mso-bidi-font-size: 8.5pt;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">pentyl-10-(1,3-dimethylhexahydro-2-pyrimidinyl)-1-decanamine and aberiamide <span style="font-size:15.0pt;mso-bidi-font-size:9.0pt; font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">N-1 <span style="font-size:15.0pt; mso-bidi-font-size:9.0pt;font-family:" times="" new="" roman";mso-fareast-font-family:="" "times="" roman";mso-ansi-language:en-us;mso-fareast-language:en-us;="" mso-bidi-language:ar-sa"="">[ <span style="font-size:14.5pt;mso-bidi-font-size: 8.5pt;font-family:" times="" new="" roman";mso-fareast-font-family:"times="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">{(E)-1-butenyl 17-dimethylcarboxamidoheptadecyl)amino) methyl]-<i style="mso-bidi-font-style: normal">N-1-methylacetamide. In addition to <span style="font-size: 13.5pt;mso-bidi-font-size:7.5pt;font-family:Arial;mso-fareast-font-family:" times="" new="" roman";="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">α- ,β-amyrin, β-sitosterol and its glucoside, three flavonoids, have also been isolated. Identification of these compounds has been done by spectral analysis and comparison with authentic samples.</span

The Neurosurgery Match: COVID Comparison and Bibliometric Analysis

Because of the effect of COVID on academic opportunities, as well as limitations on travel, away rotations and in-person interviews, COVID-related changes could impact the neurosurgical resident demographics. Our aim was to retrospectively review the demographics of the previous four years of neurosurgery residents, provide bibliometric analysis of successful applicants, and analyze for the effects of COVID on the match cycle. All AANS residency program websites were examined for a list of demographic characteristics for current post-graduate year (PGY) 1 to 4. Gathered information included gender, undergraduate and medical institution and state, medical degree status, and prior graduate programs. A total of 114 institutions and 946 residents were included in the final review. 676 (71.5%) of the residents included in the analysis were male. Of the 783 who studied within the United States, 221 (28.2%) residents stayed within the same state of his or her medical school. 104 of 555 (18.7%) residents stayed within the same state of his or her undergraduate school. Demographic information as well as geographic switching relative to medical school, undergraduate school, and hometown showed no significant changes between pre-COVID and COVID-matched cohorts overall. The median number of publications per resident significantly increased for the COVID-matched cohort (median, 1; interquartile range (IQR), 0-4.75) when compared to the non-COVID-matched cohort (median, 1; IQR, 0-3, p = 0.004) as did first author publications (median, 1; IQR, 0-1 vs median, 1; IQR, 0-1; p = 0.015), respectively. The number of residents matching into the same region in the Northeast relative to undergraduate degree was significantly greater after COVID (56 (58%) vs 36 (42%), p = 0.026). The West demonstrated a significant increase in the mean number of total publications (4.0 ± 8.5 vs 2.3 ± 4.2, p = 0.02) and first author publications (1.24 ± 2.33 vs 0.68 ± 1.47, p = 0.02) after COVID, with the increase in first author publications being significant in a test of medians. Herein we characterized the most recently matched neurosurgery applicants, paying particular attention to changes over time in relation to the onset of the pandemic. Apart from publication volume, characteristics of residents and geographical preferences did not change with the influence of COVID-induced changes in the application process