Prikaz anatomskih varijacija sfenoidnog sinusa kompjutoriziranom tomografijom

Objective: This doctoral thesis is a retrospective-prospective anatomic-radiologic study with an objective to research anatomic variations of sphenoid sinus shown by computed tomography. ----- Patients and methods: The study included 122 subjects, 58 men and 64 women. All patients underwent computed tomography examination during the usual procedures for suspected paranasal sinus diseases. The aim was to investigate the spreading of the sphenoid sinus extensions into the parts of the sphenoid bone; the anterior clinoid process; the greater wing and into the pterigoid process of sphenoid bone, as the protrusion of the optic nerve, maxillary nerve and the vidian nerve into the sphenoid sinus. Dehiscence bony partitions that can be found between nerve structures and sphenoid sinus were also researched. ----- Results: ACP pneumatization, GWS and the PP was found in 39 (31.97%), 48 (33.34%) and 62 (50.82%) patients respectively. VN protrusion, MN and ON was found in 61 (50%), 44 (56.07%) and 33 (27.05%) patients respectively and dehiscence bone septum between these neural structures and sphenoid sinus in 54 (44.26%) , 29 (23.77%) and 24 (19.67%) patients respectively. ----- Conclusion: Sphenoid sinus is highly variable. Anatomic variations of sphenoid sinus are common. Computed tomography, especially, MSCT in particular is the method of choice in the detection of anatomic variations of sphenoid sinus and is increasingly becoming the gold standard for evaluating planned preoperational endonasal, endovascular procedures on the sinuses, as also before neuro microsurgery on structures that surround the sinus, especially on the Sella turcica transsphenoid approach for removal of pituitary adenomas

Intracranial tumors in adult population of the Varaždin County (Croatia) 1996-2004: a population-based retrospective incidence study

Aim: To estimate the incidence of intracranial tumors in the adult population of the Varazdin County, Croatia, for the 1996-2004 period. - - - - - Methods: Setting: Varazdin County General Hospital and four university hospitals in Zagreb, the capital of Croatia. Study period: January 1, 1996 to December 31, 2004. Incident patients: county residents admitted for newly diagnosed intracranial tumors according to the WHO diagnostic criteria. Demographic data were extracted from the 2001 Croatian census. Incidence rates (IRs) per 100,000 person-years (p-y) and annual IRs (per 100,000 persons) were determined and compared as incidence rate ratios (IRRs) with 95% CI. - - - - - Results: For primary intracranial tumors (PITs), IR was 12.1/100,000 p-y (95% CI: 10.3-14.2), comparable in men and women. The highest incidence was recorded for glioblastoma (IR 4.8, 3.7-6.2) and meningioma (IR 3.1, 2.2-4.2). The incidence of PIT was somewhat greater than that of metastatic tumors (IRR 1.58, 95% CI: 1.22-2.05, P = 40 vs. population aged <= 39 (all IRRs with 95% CI greater than 1, P < 0.05 or < 0.001), comparable in men and women. Women were somewhat older than men at the time of diagnosis of PIT: median difference -6 years (95.1% CI: -10 to -1, P < 0.05). Annual IRs for all these tumor categories showed increasing trends over the study period. - - - - - Conclusion: Overall, there was an increasing trend in the incidence of primary intracranial tumors in the Varazdin County. Data did not allow estimation for most of the specific tumor types