Studio e progettazione di dettaglio di un sistema elettro-idraulico per posizionamento angolare di precisione di particolari meccanici rotanti

Questa tesi di laurea, svolta in collaborazione con Oto Melara S.p.a, riguarda lo studio e la progettazione di un sistema per la graduazione meccanica di una tipologia di munizioni calibro 127mm. Lo studio si inserisce nella progettazione di un nuovo complesso navale che dovrà essere in grado di gestire, oltre a una tipologia innovativa di munizioni (programmabili a contatto), anche munizioni di tipo standard (provviste di una spoletta a graduazione meccanica)

A estrutura a termo como previsor da atividade econômica real

TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.O objetivo deste trabalho é a analisar o poder de previsão da estrutura a termo da taxa de juros sobre o produto, investimento, gasto do governo, consumo das famílias, exportações, importações e IBC-BR. Será utilizada a análise de componentes principais para estimar os fatores nível, inclinação e curvatura da estrutura termo. O modelo estimado foi o de mínimos quadrados ordinários e o arcabouço usado para a análise dos dados estará relacionado principalmente aos mecanismos de transmissão da política monetária. O R2 ajustado de todos os modelos estimados foi consideravelmente alto. A curvatura foi determinante na estimação dos melhores modelos selecionados, apresentando significância em praticamente todos os modelos específicos. A inclinação teve significância em alguma defasagem apenas para o consumo das famílias, investimento e gasto do governo. Houve a evidência de um ciclo de juros de curto prazo para o produto, investimento, consumo das famílias, importações, e IBCB

A laboratory device for mesuring the method of eddy currents the diffusion coefficient of hydrogen in metals hydrogenation

A method is proposed for measuring the diffusion coefficient of hydrogen in a membrane made of a titanium alloy VT1-0 based on the use of eddy currents and an installation for its implementation is described. An eddy current sensor is located on the membrane, which is the wall of the electrolytic cell. The diffusion process is measured under the conditions of formation of titanium hydrides. The formation of titanium hydrides during hydrogenation is monitored over time by measuring the diffraction spectra. The results of the measurement of the diffusion coefficient of hydrogen by the proposed method are given in the conditions of formation of titanium hydrides in the membrane. The results can be used to determine the diffusion coefficients of hydrogen in various structural materials, in space technology, nuclear power engineering, in products subjected to hydrogenation during operation

Fate of Irgarol 1051, diuron and their main metabolites in two UK marine systems after restrictions in antifouling paints

Two major antifouling biocides used worldwide, Irgarol 1051 and diuron, and their degradation products in Shoreham Harbour and Brighton Marina, UK were studied during 2003-2004. The highest concentrations of Irgarol 1051 were 136 and 102 ng L(-1) in water and 40 and 49 ng g(-1) dry weight in sediments for Shoreham Harbour and Brighton Marina, respectively. As the degradation product of Irgarol 1051, M1 was also widespread, with the highest concentration of 59 ng L(-1) in water and 23 ng g(-1) in sediments in Shoreham Harbour, and 37 ng L(-1) in water and 5.6 ng g(-1) in sediments in Brighton Marina. The target compounds showed enhanced concentrations during the boating season (May-July), when boats were being re-painted (January-February), and where the density of pleasure crafts was high. Overall, the concentration of Irgarol 1051 decreased significantly from late 2000 to early 2004, indicating the effectiveness of controlling its concentrations in the marine environment following restricted use. Diuron was only detected in 14% of water samples, and mostly absent from sediment samples

The inverse stationary heat conduction problem for a cuboid

The heat conductivity coefficient is important characteristic which is used in various spheres. The original methodic for conductivity coefficient determination was proposed for samples in form of rectangular parallelepiped. The results of numerical solution of nonlinear heat conduction problem in heat conduction coefficient value range 0.04-5 W/(m K) with different sample relative size were presented

Short-term exposure of mice to cigarette smoke and/or residual oil fly ash produces proximal airspace enlargements and airway epithelium remodeling

Chronic obstructive pulmonary disease (COPD) is associated with inflammatory cell reactions, tissue destruction and lung remodeling. Many signaling pathways for these phenomena are still to be identified. We developed a mouse model of COPD to evaluate some pathophysiological mechanisms acting during the initial stage of the disease. Forty-seven 6- to 8-week-old female C57/BL6 mice (approximately 22 g) were exposed for 2 months to cigarette smoke and/or residual oil fly ash (ROFA), a concentrate of air pollution. We measured lung mechanics, airspace enlargement, airway wall thickness, epithelial cell profile, elastic and collagen fiber deposition, and by immunohistochemistry transforming growth factor-β1 (TGF-β1), macrophage elastase (MMP12), neutrophils and macrophages. We observed regional airspace enlargements near terminal bronchioles associated with the exposure to smoke or ROFA. There were also increases in airway resistance and thickening of airway walls in animals exposed to smoke. In the epithelium, we noted a decrease in the ciliated cell area of animals exposed to smoke and an increase in the total cell area associated with exposure to both smoke and ROFA. There was also an increase in the expression of TGF-β1 both in the airways and parenchyma of animals exposed to smoke. However, we could not detect inflammatory cell recruitment, increases in MMP12 or elastic and collagen fiber deposition. After 2 months of exposure to cigarette smoke and/or ROFA, mice developed regional airspace enlargements and airway epithelium remodeling, although no inflammation or increases in fiber deposition were detected. Some of these phenomena may have been mediated by TGF-β1

G0^0 Electronics and Data Acquisition (Forward-Angle Measurements)

The G$^0$ parity-violation experiment at Jefferson Lab (Newport News, VA) is designed to determine the contribution of strange/anti-strange quark pairs to the intrinsic properties of the proton. In the forward-angle part of the experiment, the asymmetry in the cross section was measured for $\vec{e}p$ elastic scattering by counting the recoil protons corresponding to the two beam-helicity states. Due to the high accuracy required on the asymmetry, the G$^0$ experiment was based on a custom experimental setup with its own associated electronics and data acquisition (DAQ) system. Highly specialized time-encoding electronics provided time-of-flight spectra for each detector for each helicity state. More conventional electronics was used for monitoring (mainly FastBus). The time-encoding electronics and the DAQ system have been designed to handle events at a mean rate of 2 MHz per detector with low deadtime and to minimize helicity-correlated systematic errors. In this paper, we outline the general architecture and the main features of the electronics and the DAQ system dedicated to G$^0$ forward-angle measurements.Comment: 35 pages. 17 figures. This article is to be submitted to NIM section A. It has been written with Latex using \documentclass{elsart}. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment In Press (2007

Organs on chip approach: A tool to evaluate cancer-immune cells interactions

In this paper we discuss the applicability of numerical descriptors and statistical physics concepts to characterize complex biological systems observed at microscopic level through organ on chip approach. To this end, we employ data collected on a micro uidic platform in which leukocytes can move through suitably built channels toward their target. Leukocyte behavior is recorded by standard time lapse imaging. In particular, we analyze three groups of human peripheral blood mononuclear cells (PBMC): heterozygous mutants (in which only one copy of the FPR1 gene is normal), homozygous mutants (in which both alleles encoding FPR1 are loss-of-function variants) and cells from ‘wild type’ donors (with normal expression of FPR1). We characterize the migration of these cells providing a quantitative con rmation of the essential role of FPR1 in cancer chemotherapy response. Indeed wild type PBMC perform biased random walks toward chemotherapy-treated cancer cells establishing persistent interactions with them. Conversely, heterozygous mutants present a weaker bias in their motion and homozygous mutants perform rather uncorrelated random walks, both failing to engage with their targets. We next focus on wild type cells and study the interactions of leukocytes with cancerous cells developing a novel heuristic procedure, inspired by Lyapunov stability in dynamical systems

Genomic selection for water use efficiency in Japonica rice and evaluation of different parameters implicated on the accuracy level. [P 0778]

Conjunction of high-throughput marker technologies and new statistical methods has recently given birth to a new breeding strategy called genomic selection (GS). The method use genome-wide dense marker genotyping for the prediction of genetic values (GEBV) with enough accuracy to allow selection based on GEBV alone. We present here GS for water use efficiency in rice, in the framework of a pedigree breeding scheme. The training population (TP) was composed of 284 accessions belonging to temperate and tropical japonica rice groups. The candidate population (CP) was composed of 99 F5-F7 lines derived from 36 crosses involving 32 accessions of TP. The two populations were genotyped with an average marker density of 4.8 per kb, with MAF 2.5%. Phenotypic traits considered included flowering time (FL), grain yield (GY) and nitrogen balance index (NI) under conventional irrigation (CI) and aerobic system (AS). Phenotypes were modeled using two statistical regression methods: genomic best linear unbiased prediction (GBLUP) and reproducing kernel Hilbert Space (RKHS). The models were tested with three incidence matrixes corresponding to densities of 4.8, 9.5 and 13.8 marker per kb, and to linkage disequilibrium (LD) thresholds of r2≤1, r²<0.98 and r²<0.81 to investigate effect of the method and level of LD. Results of interpopulation prediction in rice breeding provided accuracies of GEBV prediction reasonably high for GY (0.41; Sd=0.03) and for NI (0.36; Sd=0.04), low for FL (0.26; Sd = 0.07), that need to be optimized by exploring potential effect of population structure within both TP and CP. (Texte integral