Escherichia coli Common Pilus (ECP) Targets Arabinosyl Residues in Plant Cell Walls to Mediate Adhesion to Fresh Produce Plants

International audienceBackground: Bacterial fimbriae mediate binding to host tissue through specific interactions. Results: ECP interacts with arabinosyl residues in pectin and other plant cell wall components. Conclusion: ECP-arabinan interactions facilitate binding of E. coli to plant hosts. Significance: The prevalence of arabinan targets in produce plants together with ECP expression may explain the association of pathogenic bacteria in edible plants

Nuclear Matrix Elements of Axial-Charge Exchange Currents Derived in Heavy-Fermion Chiral Perturbation Theory

We calculate shell-model matrix elements of the axial-charge exchange current operators that have been obtained up to the next-to-leading order from heavy-fermion chiral perturbation theory. It is found that loop corrections to the soft one-pion-exchange contribution are small (around 10 \%) and have no significant dependence on the nuclear mass number or on the valence-nucleon orbits. These results render further support to the chiral-filtering conjecture.Comment: 19 pages, LaTeX, SNUTP 94-29, USC(NT)-94-

Qualité de la viande pour un avenir durable - Qualité sensorielle, normes et solutions innovantes pour le commerce

Publication history: Published - 28 April 2020.This meeting/workshop has been organized by the United Nations Economic Commission for Europe (UNECE) in collaboration with the organizers of the 2019 International Congress of Meat Science and Technology (ICoMST). The international UNECE meeting/workshop was focused on sustainable meat quality and standards; the latest developments in the area of eating quality; innovative solutions for sustainable meat trade; food integrity, traceability of meat and blockchain technologies; as well as sustainable solutions to food loss/waste prevention in the meat sector. Presentations of speakers are available on http://www.unece.org/index.php?id=51442

The Lab 6.5 : Laura Kavanaugh and Ian Birse : The Fortress of History

"For their LAB project, Ian Birse and Laura Kavanagh collaborate in discovering what is underfoot. Walking the streets of Victoria, they documented the discovery of discarded objects, photographing them on-site as well and recording a sonic snapshot of sounds at each location. In the process, the artists present performances for accidental audiences." -- Publisher's website

Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression

Abstract Rectal use of a 1% tenofovir (TFV) gel is currently being evaluated for HIV prevention. While careful assessment of mucosal safety of candidate microbicides is a primary concern, tools to assess mucosal toxicity are limited. Mass spectrometry-based proteomics is a sensitive and high-throughput technique that can provide in-depth information on inflammation processes in biological systems. In this study, we utilized a proteomics approach to characterize mucosal responses in study participants involved in a phase 1 clinical trial of a rectal TFV-based gel. Project Gel was a phase 1 randomized (1:1), double-blind, multisite, placebo-controlled trial in which 24 participants received rectal TFV or a universal placebo [hydroxyethyl cellulose (HEC)] over a course of 8 daily doses. Rectal mucosal swabs were collected after 0, 1, and 8 doses and were analyzed by label-free tandem mass spectrometry. Differential protein expression was evaluated using a combination of paired (time-effects) and unpaired (across study arm) t-tests, and multivariate [least absolute shrinkage and selection operator (LASSO)] modeling. Within the TFV arm, 7% (17/249, p < .05) and 10% (25/249, p < .05) of total proteins changed after 1 and 8 daily applications of TFV gel, respectively, compared to 3% (7/249, p < .05) and 6% (16/249, p < .05) in the HEC arm. Biofunctional analysis associated TFV use with a decrease in epidermal barrier proteins (adj. p = 1.21 × 10−10). Multivariate modeling identified 13 proteins that confidently separated TFV gel users (100% calibration and 96% cross-validation accuracy), including the epithelial integrity factors (FLMNB, CRNN, CALM), serpins (SPB13, SPB5), and cytoskeletal proteins (VILI, VIME, WRD1). This study suggested that daily rectal applications of a 1% TFV gel may be associated with mucosal proteome changes involving epidermal development. Further assessment of more extended use of TFV-gel is recommended to validate these initial associations

A Relatively Small Collection : Exhibition and Lending Library of Audio Cassette Work Presented at Ace Art Inc.

A catalogue made to accompany an exhibition and lending library of audio cassette works by twenty-nine artists. In their brief curatorial statement, Elliot and Dumontier examine connections between audio technology and concepts of recording/memory. Includes artists' statements, many of which outline the methods and techniques used to create specific works. Biographical notes. 1 bibl. ref. The collection is available for consultation (see doc. 21009)

A Relatively Small Collection

Participating artists produced sound-based art of varying lengths to be shared with the public through an exhibition, a lending library and a listening centre. The range of work includes storytelling, spoken word, instrumental music, interviews, rock & roll, and audio-collages. Originally conceived as a temporary collection, the works were returned to participating artists at the end of the exhibition. In 2002, the collection was reconstituted and acquired by Artexte