Gemeinsam besser lernen?!

Die bildungspolitische Forderung nach einer gemeinsamen Beschulung aller Schüler stellt die Didaktik (nicht nur) im Mathematikunterricht vor große Herausforderungen. Der Vortrag skizziert die zentralen Forschungsbefunde der Mathematikdidaktik aus der Sonderpädagogik und in integrativen Settings für ein erfolgreiches Lernen aller Schüler. Daraus werden didaktisch-methodische Gestaltungsmöglichkeiten für einen Mathematikunterricht in heterogenen Klassen abgeleitet

Discovery of an OVI Emitting Nebula around the Hot White Dwarf KPD 0005+5106

A survey of diffuse interstellar sight lines observed with the Far Ultraviolet Spectroscopic Explorer has led to the serendipitous discovery of a high-ionization nebula around the hot white dwarf KPD 0005+5106. The nebula has an OVI 1032A surface brightness of up to 25,000 photons/s/cm^2/sr, making it the brightest region of extended OVI emission in our survey. Photoionization models using the incident white dwarf continuum successfully reproduce the observed OVI intensity. The OVI emission arises in the highly ionized inner region of a planetary nebula around KPD 0005+5106. This newly discovered nebula may be one member of a class of high-ionization planetary nebulae that are difficult to detect in the optical, but which can be easily identified in the ultraviolet.Comment: accepted for publication in ApJL, 11 pages including 2 figure

Spain, China, and Japan in Manila, 1571-1644

This book offers a new perspective on the connected histories of Spain, China, and Japan as they emerged and developed following Manila’s foundation as the capital of the Spanish Philippines in 1571. Examining a wealth of multilingual primary sources, Birgit Tremml-Werner shows that crosscultural encounters not only shaped Manila’s development as a “Eurasian” port city, but also had profound political, economic, and social ramifications for the three premodern states. Combining a systematic comparison with a focus on specific actors during this period, this book addresses many long-held misconceptions and offers a more balanced and multifaceted view of these nations’ histories

Overproduction and characterization of a recombinant D -amino acid oxidase from Arthrobacter protophormiae

A screening of soil samples for d-amino acid oxidase (d-AAO) activity led to the isolation and identification of the gram-positive bacterium Arthrobacter protophormiae. After purification of the wild-type d-AAO, the gene sequence was determined and designated dao. An alignment of the deduced primary structure with eukaryotic d-AAOs and d-aspartate oxidases showed that the d-AAO from A. protophormiae contains five of six conserved regions; the C-terminal type 1 peroxisomal targeting signal that is typical for d-AAOs from eukaryotic origin is missing. The dao gene was cloned and expressed in Escherichia coli. The purified recombinant d-AAO had a specific activity of 180U mg protein−1 for d-methionine and was slightly inhibited in the presence of l-methionine. Mainly, basic and hydrophobic d-amino acids were oxidized by the strictly enantioselective enzyme. After a high cell density fermentation, 2.29 × 106U of d-AAO were obtained from 15l of fermentation brot