Financial disclosure and the Board: A case for non-independent directors

In listed companies, the Board of directors has ultimate responsibility for information disclosure. The conventional wisdom is that director independence is an essential factor in improving the quality of that disclosure. In a sense, this approach subordinates expertise to independence. We argue that effective certification may require firm-specific expertise, in particular for intangible-intensive business models. However, this latter form of expertise is negatively related to independence as it is commonly measured and evaluated. Accordingly, there exists an optimal share of independent directors for each company, related to the level of intangible resources.

New experimental limits on neutron - mirror neutron oscillations in the presence of mirror magnetic field

Present probes do not exclude that the neutron ($n$) oscillation into mirror neutron ($n'$), a sterile state exactly degenerate in mass with the neutron, can be a very fast process, in fact faster than the neutron decay itself. This process is sensitive to the magnetic field. Namely, if the mirror magnetic field $\vec{B}'$ exists at the Earth, $n-n'$ oscillation probability can be suppressed or resonantly amplified by the applied magnetic field $\vec{B}$, depending on its strength and on the angle $\beta$ between $\vec{B}$ and $\vec{B}'$. We present the results of ultra-cold neutron storage measurements aiming to check the anomalies observed in previous experiments which could be a signal for $n-n'$ oscillation in the presence of mirror magnetic field $B'\sim 0.1$~G. Analyzing the experimental data on neutron loses, we obtain a new lower limit on $n-n'$ oscillation time $\tau_{nn'} > 17$ s (95 % C.L.) for any $B'$ between 0.08 and 0.17 G, and $\tau_{nn'}/\sqrt{\cos\beta} > 27$s (95 % C.L.) for any $B'$ in the interval ($0.06\div0.25$) G

Inhibition of in-stent stenosis by oral administration of bindarit in porcine coronary arteries

<p><b>Objective:</b> We have previously demonstrated that bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs), is effective in reducing neointimal formation in rodent models of vascular injury by reducing smooth muscle cell proliferation and migration and neointimal macrophage content, effects associated with the inhibition of MCP-1/CCL2 production. The aim of the current study was to evaluate the efficacy of bindarit on in-stent stenosis in the preclinical porcine coronary stent model.</p> <p><b>Methods and Results:</b> One or 2 bare metal stents (Multi-Link Vision, 3.5 mm) were deployed (1:1.2 oversize ratio) in the coronary arteries of 42 pigs (20 bindarit versus 22 controls). Bindarit (50 mg/kg per day) was administered orally from 2 days before stenting until the time of euthanasia at 7 and 28 days. Bindarit caused a significant reduction in neointimal area (39.4%, P<0.001, n=9 group), neointimal thickness (51%, P<0.001), stenosis area (37%, P<0.001), and inflammatory score (40%, P<0.001) compared with control animals, whereas there was no significant difference in the injury score between the 2 groups. Moreover, treatment with bindarit significantly reduced the number of proliferating cells (by 45%, P<0.05; n=6 group) and monocyte/macrophage content (by 55%, P<0.01; n=5–6 group) in stented arteries at day 7 and 28, respectively. These effects were associated with a significant (P<0.05) reduction of MCP-1 plasma levels at day 28. In vitro data showed that bindarit (10–300 micromol/L) reduced tumor necrosis factor-alpha (50 ng/mL)–induced pig coronary artery smooth muscle cell proliferation and inhibited MCP-1 production.</p> <p><b>Conclusion:</b> Our results show the efficacy of bindarit in the prevention of porcine in-stent stenosis and support further investigation for clinical application of this compound.</p&gt

Measurements of Surface River Doppler Velocities With Along-Track InSAR Using a Single Antenna

Nowadays, a worldwide database containing the historical and reliable data concerning the water surface speed of rivers is not available and would be highly desirable. In order to meet this requirement, the present work is aimed at the design of an estimation procedure for water flow velocity by means of synthetic aperture radar (SAR) data. The main technical aspect of the proposed procedure is that an along-track geometry is synthesized using a single antenna and a single image. This is achieved by exploiting a multichromatic analysis in the Doppler domain. The application of this approach allows us to obtain along-track interferometry equivalent virtual baselines much lower than the equivalent baseline corresponding to the decorrelation time of raw data preserving data coherence. The performance analysis, conducted on live airborne full-polarimetric SAR data, highlights the effectiveness of the proposed approach in providing reliable river surface velocity estimates without the need of multiple passes on the observed scene

An Unusual Case of Adrenal Metastasis from Colorectal Cancer: Computed Tomography and Fluorine 18-Fluoro-Deoxy-Glucose Positron Emission Tomography-Computed Tomography Features and Literature Review

Incidentally discovered adrenal masses are a common diagnostic problem. While computed tomography (CT) and magnetic resonance (MR) imaging can adequately characterize most benign or malignant adrenal masses, in some cases the results are indeterminate. We report and discuss a case of an adrenal metastasis with misleading clinical and CT features, in which an abnormal metabolic uptake detected through fluorine 18-fluoro-deoxy-glucose positron emission tomography (18F-FDG PET)-CT raised the suspicion of adrenal metastasis relatively early compared with apparently normal results on repeated follow-up CT examinations

Water level measurements using COSMO-SkyMed synthetic aperture radar

In this work, temporal series of Synthetic Aperture Radar (SAR) data are used to estimate water elevations. The proposed method is based on a Sub-Pixel Offset Tracking (technique) to retrieve the displacement of the double-bounce scattering effect of man-made structures located in the proximity of the water surface. The experimental setup is focused on the cases of the Mosul dam in Iraq and the Missouri river in Kansas City. The proposed approach is applied to real data from the COSMO-SkyMed program. Results validated with in-situ and satellite radar altimeter measurements prove the effectiveness of the proposed method in measuring the water levels

Monitoring of Critical Infrastructures by Micromotion Estimation: The Mosul Dam Destabilization

In this article, we propose a new procedure to monitor critical infrastructures. The proposed approach is applied to COSMO-SkyMed data, with the aim to monitor the destabilization of the Mosul dam. Such a dam represents the largest hydraulic facility of Iraq and is located on the Tigris river. The destructive potential of the wave that would be generated, in the event of the dam destruction, could have serious consequences. If the concern for human lives comes first, the concern for cultural heritage protection is not negligible, since several archaeological sites are located around the Mosul dam. The proposed procedure is an in-depth modal assessment based on the micromotion estimation, through a Doppler subapertures tracking and a multichromatic analysis. The method is based initially on the persistent scatterers interferometry that is also discussed for completeness and validation. The modal analysis has detected the presence of several areas of resonance that could mean the presence of cracks, and the results have shown that the dam is still in a strong destabilization. Moreover, the dam appears to be divided into two parts: the northern part is accelerating rapidly while the southern part is decelerating and a main crack in this north south junction is found. The estimated velocities through the PS-InSAR technique show a good agreement with the GNSS in situ measurements, resulting in a very high correlation coefficient and showing how the proposed procedure works efficiently