Application of Sentinel Lymph Node Biopsy in Cutaneous Basosquamous Carcinoma

Basosquamous carcinoma of the skin is a relatively rare cutaneous neoplasm that has significant metastatic potential and a metastatic rate greater than that of basal cell and squamous cell carcinoma. We describe the use of lymphatic mapping and sentinel lymph node biopsy in a 63-year-old man after identification of basosquamous carcinoma. Sentinel lymph node biopsy, which is a standard tool to detect regional lymphatic metastasis in cutaneous melanoma, has been rarely employed to detect lymphatic metastasis of basosquamous carcinoma. The approach was successful in detecting a regional lymphatic metastasis of two nodal basins with minor morbidity. Sentinel lymph node biopsy may be useful for certain high-risk lesions of basosquamous carcinoma

ELEKTROIONOTHERAPY - A NEW PATTERN OF VENOUS ULCERS HEALING

Venous ulcers are frequent, chronic disease which requires the constant therapeutic surveillance and it significantly influences the quality of life of the diseased. Also, the therapy prescribed is often without success and is very expensive. In dermatological practise, beside medicaments, phisical therapy is also applied but with varying success. In the recent years, electroionotherapy has been used as a revolutionary inovation in the modern biomedical technology. The investigation included 15 pacients with venous ulcers which were treated with use of an apparatus generating electroionic flow. During the treatment, the parameters of ulcers (surface, depth, volume, fibrin deposits, exudation, granulation, epithelization), the surrounding of ulcers, as well as subjective symptoms (pain and pruritus) were monitored. All parameters were monitored clinically at the begining, during and at the end of the treatment, when they were scored. The results were statistically analyzed. At the end of the investigation, all the parameters improved and these improvements were statistically significant

Does incomplete excision of basal cell carcinoma of the eyelid mean tumor recurrence?

INTRODUCTION: Basal cell carcinoma is the most common tumor of the eyelid. In this region, reconstruction is complex and damage to healthy tissue should be minimal. Objective: To define the relationship between margin clearance at excision and the recurrence rate of basal cell carcinoma of the eyelid. METHODS: This prospective study was conducted with 111 patients submitted to surgery for basal cell carcinoma of the eyelid between 2001 and 2003 and followed up for a period of five years. The patients were evaluated according to age, tumor site, recurrence rate and margin clearance at excision. RESULTS: No significant association was found between incomplete tumor excision and recurrence except in patients under 56 years of age, female patients and in the case of tumors of the medial canthus. CONCLUSION: A risk of recurrence in incompletely excised basal cell carcinomas of the eyelid was only confirmed in younger patients, females and for tumors of the medial canthus

GIANT CONGENITAL NEVUS – CASE REPORT

Congenital nevomelanocitic nevi (CN) are benign melanocitic proliferations present at birth. The incidence of giant CN is 0,002% in the newborns. The paper presents the case of a 20-year old female with giant CN on the skin of the right hand. Dermoscopy is very useful in differential diagnosis of pigmented skin lesions. Dermoscopic characteristics of CN are the presence of uniform globules - the "pebble stone" pattern. Giant CN overtaking more than 5% of the skin has an increased risk of malignant melanoma. Possible therapy modalities for CN are: excision with grafts, dermabrasion, curettage and laser. Periodical check-ups are necessary

Efficacy of imiquimod 3.75% cream for the treatment of solar lentigo

In our patient imiquimod 3.75% cream showed an acceptable tolerability profile with the advantage of being self-applied by the patient, showing an efficacy not only at the level of actinic keratosis and NMSCs, but also in case solar lentigo (SL). Further studies are necessary to validate the use of imiquimod also for benign skin lesions, associated with chronic skin photodamage