21 research outputs found
Magnetic shielding accelerates the proliferation of human neuroblastoma cell by promoting G1-phase progression
Organisms have been exposed to the geomagnetic field (GMF) throughout evolutionary history. Exposure to the hypomagnetic field (HMF) by deep magnetic shielding has recently been suggested to have a negative effect on the structure and function of the central nervous system, particularly during early development. Although changes in cell growth and differentiation have been observed in the HMF, the effects of the HMF on cell cycle progression still remain unclear. Here we show that continuous HMF exposure significantly increases the proliferation of human neuroblastoma (SH-SY5Y) cells. The acceleration of proliferation results from a forward shift of the cell cycle in G1-phase. The G2/M-phase progression is not affected in the HMF. Our data is the first to demonstrate that the HMF can stimulate the proliferation of SH-SY5Y cells by promoting cell cycle progression in the G1-phase. This provides a novel way to study the mechanism of cells in response to changes of environmental magnetic field including the GMF
Information storing by biomagnetites
Since the discovery of the presence of biogenic magnetites in living
organisms, there have been speculations on the role that these biomagnetites
play in cellular processes. It seems that the formation of biomagnetite
crystals is a universal phenomenon and not an exception in living cells. Many
experimental facts show that features of organic and inorganic processes could
be indistinguishable at nanoscale levels. Living cells are quantum "devices"
rather than simple electronic devices utilizing only the charge of conduction
electrons. In our opinion, due to their unusual biophysical properties, special
biomagnetites must have a biological function in living cells in general and in
the brain in particular. In this paper we advance a hypothesis that while
biomagnetites are developed jointly with organic molecules and cellular
electromagnetic fields in cells, they can record information about the Earth's
magnetic vector potential of the entire flight in migratory birds.Comment: 17 pages, 3 figure