Ultra-compact lithium niobate photonic chip for high-capacity and energy-efficient wavelength-division-multiplexing transmitters

Recently, high-performance thin-film lithium niobate optical modulators have emerged that, together with advanced multiplexing technologies, are highly expected to satisfy the ever-growing demand for high-capacity optical interconnects utilizing multiple channels. Accordingly, in this study, a compact lithium-niobate-on-insulator (LNOI) photonic chip was adopted to establish four-channel wavelength-division-multiplexing (WDM) transmitters, comprising four optical modulators based on ultracompact 2 × 2 Fabry-Perot cavities and a four-channel WDM filter based on multimode waveguide gratings. The fabricated chip with four wavelength channels has a total footprint as compact as 0.3 × 2.8 mm2, and exhibits an excess loss of ~0.8 dB as well as low inter-channel crosstalk of < –22 dB. Using this LNOI photonic chip, high-capacity data transmissions of 320 Gbps (4 × 80 Gbps) on-off-keying signals and 400 Gbps (4 × 100 Gbps) four-level pulse amplitude signals were successfully realized with the ultra-low power consumption of 11.9 fJ/bit

Path Planning Based on NURBS for Hyper-Redundant Manipulator Used in Narrow Space

Hyper-redundant manipulators with multiple degrees of freedom have special application prospects in narrow spaces, such as detection in small spaces in aerospace, rescue on-site disaster relief, etc. In order to solve the problems of complex obstacle avoidance planning and inverse solution selection of a hyper-redundant robot in a narrow space, a cubic B-spline curve based on collision-free trajectory using environmental edge information is planned. Firstly, a hyper-redundant robot composed of four pairs of double UCR (Universal-Cylindrical-Revolute) parallel mechanisms (2R1T, 2 Rotational DOFs and 1 Translation DOF) in series to realize flexible obstacle avoidance motion in narrow space is designed. The trajectory point envelope of a single UCR and the workspace of a single pair of UCR in Cartesian space based on the motion constraint boundaries of each joint are obtained. Then, the constraint control points according to the edge information of the obstacle are obtained, and the obstacle avoidance trajectory in the constrained space is planned by combining the A* algorithm and cubic B-spline algorithm. Finally, a variety of test scenarios are built to verify the obstacle avoidance planning algorithm. The results show that the proposed algorithm reduces the computational complexity of the obstacle avoidance process and enables the robot to complete flexible obstacle avoidance movement in the complex narrow space

Path Planning Based on NURBS for Hyper-Redundant Manipulator Used in Narrow Space

Hyper-redundant manipulators with multiple degrees of freedom have special application prospects in narrow spaces, such as detection in small spaces in aerospace, rescue on-site disaster relief, etc. In order to solve the problems of complex obstacle avoidance planning and inverse solution selection of a hyper-redundant robot in a narrow space, a cubic B-spline curve based on collision-free trajectory using environmental edge information is planned. Firstly, a hyper-redundant robot composed of four pairs of double UCR (Universal-Cylindrical-Revolute) parallel mechanisms (2R1T, 2 Rotational DOFs and 1 Translation DOF) in series to realize flexible obstacle avoidance motion in narrow space is designed. The trajectory point envelope of a single UCR and the workspace of a single pair of UCR in Cartesian space based on the motion constraint boundaries of each joint are obtained. Then, the constraint control points according to the edge information of the obstacle are obtained, and the obstacle avoidance trajectory in the constrained space is planned by combining the A* algorithm and cubic B-spline algorithm. Finally, a variety of test scenarios are built to verify the obstacle avoidance planning algorithm. The results show that the proposed algorithm reduces the computational complexity of the obstacle avoidance process and enables the robot to complete flexible obstacle avoidance movement in the complex narrow space

Injection by Hydrostatic Pressure in Conjunction with Electrokinetic Force on a Microfluidic Chip

A simple method was developed for injecting a sample on a cross-form microfluidic chip by means of hydrostatic pressure combined with electrokinetic forces. The hydrostatic pressure was generated simply by adjusting the liquid level in different reservoirs without any additional driven equipment such as a pump. Two dispensing strategies using a floating injection and a gated injection, coupled with hydrostatic pressure loading, were tested. The fluorescence observation verified the feasibility of hydrostatic pressure loading in the separation of a mixture of fluorescein sodium salt and fluorescein isothiocyanate. This method was proved to be effective in leading cells to a separation channel for single cell analysis

Device for Measuring Contact Reaction Forces during Animal Adhesion Landing/Takeoff from Leaf-like Compliant Substrates

A precise measurement of animal behavior and reaction forces from their surroundings can help elucidate the fundamental principle of animal locomotion, such as landing and takeoff. Compared with stiff substrates, compliant substrates, like leaves, readily yield to loads, presenting grand challenges in measuring the reaction forces on the substrates involving compliance. To gain insight into the kinematic mechanisms and structural–functional evolution associated with arboreal animal locomotion, this study introduces an innovative device that facilitates the quantification of the reaction forces on compliant substrates, like leaves. By utilizing the stiffness–damping characteristics of servomotors and the adjustable length of a cantilever structure, the substrate compliance of the device can be accurately controlled. The substrate was further connected to a force sensor and an acceleration sensor. With the cooperation of these sensors, the measured interaction force between the animal and the compliant substrate prevented the effects of inertial force coupling. The device was calibrated under preset conditions, and its force measurement accuracy was validated, with the error between the actual measured and theoretical values being no greater than 10%. Force curves were measured, and frictional adhesion coefficients were calculated from comparative experiments on the landing/takeoff of adherent animals (tree frogs and geckos) on this device. Analysis revealed that the adhesion force limits were significantly lower than previously reported values (0.2~0.4 times those estimated in previous research). This apparatus provides mechanical evidence for elucidating structural–functional relationships exhibited by animals during locomotion and can serve as an experimental platform for optimizing the locomotion of bioinspired robots on compliant substrates.ISSN:2313-767

Fabrication of two-weir structure-based packed columns for on-chip solid-phase extraction of DNA

Microchip-based packed column SPE of DNA was performed using the microfabricated two-weir structure within a microchannel. We developed two methods to fabricate the two-weir structured glass chips: a "two-side etching/alignment" method and a simplified "one-side/two-step etching" method. The former rnethod required a straightforward alignment step, while the latter approach comprised a simplified wet etching process using paraffin wax as the temporary protective layer. Both methods were convenient and rapid as compared to the previous approaches. Through a reversibly sealed bead-introduction channel, beads can be fed into or out of the chip columns, thus enabling refreshment of the packing materials. Using the proposed chip columns, highly efficient,lambda-DNA extractions (average recovery > 80%) were performed with good chip-to-chip reproducibility (RSD < 10%). The on-chip SPE procedure was completed within 15 min at the flow rate of 3 mu L/min and the bulk of the loaded DNA was eluted within a small volume of similar to 8 mu L. Application of the microchip-based packed columns was demonstrated by purifying PCR-amplifiable genomic DNA from human hepatocellular carcinoma (HepG2) cells and human whole blood samples

Studying drug-plasma protein interactions by two-injector microchip electrophoresis frontal analysis

We developed a simple, rapid, and sensitive two-injector microchip electrophoresis frontal analysis (MCE-FA) method for studying drug-plasma protein interactions. In this method, large volumes of a reference sample and drug-plasma protein mixture were simultaneously introduced into the respective sections of the microchannel through the separated injectors and then electrophoresed. Since the reference sample did not meet with the interacting species during migration, it could be used as an external standard. The interaction between heparin and HSA was quantitatively characterized as a model system. The binding constant was found to be (1.53 +/- 0.01) X 10(4) M-1