An Updated Search of Steady TeV γ−\gamma-Ray Point Sources in Northern Hemisphere Using the Tibet Air Shower Array

Using the data taken from Tibet II High Density (HD) Array (1997 February-1999 September) and Tibet-III array (1999 November-2005 November), our previous northern sky survey for TeV $\gamma-$ray point sources has now been updated by a factor of 2.8 improved statistics. From $0.0^{\circ}$ to $60.0^{\circ}$ in declination (Dec) range, no new TeV $\gamma-$ray point sources with sufficiently high significance were identified while the well-known Crab Nebula and Mrk421 remain to be the brightest TeV $\gamma-$ray sources within the field of view of the Tibet air shower array. Based on the currently available data and at the 90% confidence level (C.L.), the flux upper limits for different power law index assumption are re-derived, which are approximately improved by 1.7 times as compared with our previous reported limits.Comment: This paper has been accepted by hepn

Synthesis and Characterization of Novel Purpurinimides as Photosensitizers for Photodynamic Therapy

A series of novel purpurinimides with long wavelength absorption were designed and synthesized to develop novel and potential photosensitizers. These compounds were investigated through reduction, oxidation, rearrangement reaction and amidation reactions of methyl pheophorbide a. They demonstrated a considerable bathochromic shift of the major absorption band in the red region of the optical spectrum (695–704 nm). Newly synthesized purpurinimides were screened for their antitumor activities, and showed higher photodynamic efficiency against A549 cell lines as compared to purpurin-18 methyl ester. The results revealed the novel purpurinimides could be potential photosensitizers

The investigation involved face-to-face interviews based on self-designed structured questionnaires and subsequente clinical breast examinations.

<p>And subjects with suspected positive physical signs would receive further ultrasonic and X-ray examinations and possible biopsies. After the above proceeds, breast cancer cases were identified. In total, 124,758 were collected in the study, and because of information loss, 122,058 cases were included in the final analysis.</p

Pathological information on cases of breast cancer.

<p>Pathological information on cases of breast cancer.</p

Multivariate logistic analysis of breast cancer-related factors among women.

<p>Multivariate logistic analysis of breast cancer-related factors among women.</p

Detailed distributions of the breast cancer cases from the four survey areas by age are shown in this figure.

<p>Overall, breast cancer cases identified in this study were primarily diagnosed in the 40–45 and 45–50 year age groups.</p

Random samples were obtained through multi-stage stratified cluster sampling.

<p>Shandong, Jiangsu, Hebei and Tianjin were selected as the sampling provinces because these provinces were manliy resident areas of Han ethnic group. And counties/regions and villages/communities were subsequently randomly selected from each province. Totally, 124,758 female, 1.5 times of the required sample size, were selected as study population. And the details of sampling information were shown in this figure.</p

Association between chronic diseases and breast cancer.

<p>Association between chronic diseases and breast cancer.</p

Related factors of demographic variables of breast cancer.

<p>Related factors of demographic variables of breast cancer.</p

Explanation of terms used in the questionnaire.

<p>Explanation of terms used in the questionnaire.</p