16 research outputs found
A new in vitro mouse oligodendrocyte precursor cell migration assay reveals a role for integrin-linked kinase in cell motility
Full text linkMODELS OF LOW REYNOLDS NUMBER SWIMMERS INSPIRED BY CELL BLEBBING
No full textAbstract. Eukaryotic cells move through the complex micro-environment of a tissue either by attaching to the extracellular matrix – sometimes degrading it locally – and pulling themselves along, or by squeezing through the matrix by appropriate sequences of shape changes. Some cells can even swim by shape changes, and one mode used is called blebbing, in which a cell creates a small hemispherical protrusion that may grow to incorporate the entire cell volume or may be reabsorbed into the primary volume. Herein we develop and analyze several models for swimming at low Reynolds number inspired by cell blebbing. These models comprise several connected spheres, and each connected pair of spheres can exchange volume with their complement in the pair. We show that the cell can propel itself through the fluid using a suitable sequence of volume exchanges, and we evaluate the efficiency of this mode of swimming
p190A inactivating mutations cause aberrant RhoA activation and promote malignant transformation via the Hippo-YAP pathway in endometrial cancer
No full textLack of NG2 exacerbates neurological outcome and modulates glial responses after traumatic brain injury
No full textCan Descriptors of the Electron Density Distribution Help To Distinguish Functional Groups?
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Oligodendroglial p130Cas Is a Target of Fyn Kinase Involved in Process Formation, Cell Migration and Survival
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